C W Ritchie

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi request reprint Metaanalysis of randomized trials of the efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer disease
    Craig W Ritchie
    Department of Psychiatry and Behavioural Science, Royal Free and University College Medical School, University College London, Royal Free Campus, Rowland Hill Street, London, UK NW3 2PF
    Am J Geriatr Psychiatry 12:358-69. 2004
  2. ncbi request reprint Metal-protein attenuating compounds and Alzheimer's disease
    Craig W Ritchie
    Royal Free and University College Medical School, Metabolic and Clinical Trials Unit, Department of Mental Health Sciences, Royal Free Campus, University College London, Rowland Hill Street, London, NW3 2PF, UK
    Expert Opin Investig Drugs 13:1585-92. 2004
  3. ncbi request reprint A comparison of the efficacy and safety of olanzapine and risperidone in the treatment of elderly patients with schizophrenia: an open study of six months duration
    C W Ritchie
    Metabolic and Clinical Trials Unit, Department of Mental Health Sciences, Royal Free and University College Medical School, London, UK
    Int J Geriatr Psychiatry 21:171-9. 2006
  4. ncbi request reprint The impact upon extra-pyramidal side effects, clinical symptoms and quality of life of a switch from conventional to atypical antipsychotics (risperidone or olanzapine) in elderly patients with schizophrenia
    C W Ritchie
    Department of Psychiatry and Behavioural Sciences, Royal Free and University College Medical School, London, UK
    Int J Geriatr Psychiatry 18:432-40. 2003
  5. ncbi request reprint A systematic review of the scientific evidence for the efficacy of a palliative care approach in advanced dementia
    E L Sampson
    Metabolic and Clinical Trials Unit, Department of Psychiatry and Behavioural Sciences, Royal Free Campus, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK
    Int Psychogeriatr 17:31-40. 2005
  6. doi request reprint Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta
    Paul A Adlard
    Oxidation Biology Laboratory, The Mental Health Research Institute of Victoria, Parkville, Victoria 3052, Australia
    Neuron 59:43-55. 2008
  7. ncbi request reprint A randomized, double-blind, placebo-controlled trial of donepezil hydrochloride (Aricept) for reducing the incidence of postoperative delirium after elective total hip replacement
    Elizabeth L Sampson
    Metabolic and Clinical Trials Unit, Department of Mental Health Sciences, Royal Free and University College Medical School, London, UK
    Int J Geriatr Psychiatry 22:343-9. 2007
  8. doi request reprint Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial
    Lars Lannfelt
    Department of Public Health and Geriatrics, Uppsala University Hospital, Uppsala, Sweden
    Lancet Neurol 7:779-86. 2008
  9. ncbi request reprint Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial
    Craig W Ritchie
    Departments of Pathology, The University of Melbourne, The Mental Health Research Institute of Victoria, Parkville, Victoria, Australia
    Arch Neurol 60:1685-91. 2003
  10. ncbi request reprint The incidence of delirium associated with orthopedic surgery: a meta-analytic review
    Angela J Bruce
    Waitemata District Health Board, Auckland, New Zealand
    Int Psychogeriatr 19:197-214. 2007

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Metaanalysis of randomized trials of the efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer disease
    Craig W Ritchie
    Department of Psychiatry and Behavioural Science, Royal Free and University College Medical School, University College London, Royal Free Campus, Rowland Hill Street, London, UK NW3 2PF
    Am J Geriatr Psychiatry 12:358-69. 2004
    ..However, both galantamine and rivastigmine were associated with a greater risk of trial dropout than placebo, especially at higher dosing levels...
  2. ncbi request reprint Metal-protein attenuating compounds and Alzheimer's disease
    Craig W Ritchie
    Royal Free and University College Medical School, Metabolic and Clinical Trials Unit, Department of Mental Health Sciences, Royal Free Campus, University College London, Rowland Hill Street, London, NW3 2PF, UK
    Expert Opin Investig Drugs 13:1585-92. 2004
    ..This article will discuss the scientific rationale behind the use of metal-protein attenuating compounds in Alzheimer's disease and summarise the available clinical trial data...
  3. ncbi request reprint A comparison of the efficacy and safety of olanzapine and risperidone in the treatment of elderly patients with schizophrenia: an open study of six months duration
    C W Ritchie
    Metabolic and Clinical Trials Unit, Department of Mental Health Sciences, Royal Free and University College Medical School, London, UK
    Int J Geriatr Psychiatry 21:171-9. 2006
    ....
  4. ncbi request reprint The impact upon extra-pyramidal side effects, clinical symptoms and quality of life of a switch from conventional to atypical antipsychotics (risperidone or olanzapine) in elderly patients with schizophrenia
    C W Ritchie
    Department of Psychiatry and Behavioural Sciences, Royal Free and University College Medical School, London, UK
    Int J Geriatr Psychiatry 18:432-40. 2003
    ..Trials in the elderly have been either retrospective, small, of short duration or of a single-arm design...
  5. ncbi request reprint A systematic review of the scientific evidence for the efficacy of a palliative care approach in advanced dementia
    E L Sampson
    Metabolic and Clinical Trials Unit, Department of Psychiatry and Behavioural Sciences, Royal Free Campus, Royal Free and University College Medical School, Rowland Hill Street, London NW3 2PF, UK
    Int Psychogeriatr 17:31-40. 2005
    ..Government reports and by the Alzheimer's Society (UK). Our objective was to perform a systematic review of the scientific literature regarding the efficacy of a palliative care model in patients with dementia...
  6. doi request reprint Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta
    Paul A Adlard
    Oxidation Biology Laboratory, The Mental Health Research Institute of Victoria, Parkville, Victoria 3052, Australia
    Neuron 59:43-55. 2008
    ..The speed of recovery of the animals underscores the acutely reversible nature of the cognitive deficits associated with transgenic models of AD...
  7. ncbi request reprint A randomized, double-blind, placebo-controlled trial of donepezil hydrochloride (Aricept) for reducing the incidence of postoperative delirium after elective total hip replacement
    Elizabeth L Sampson
    Metabolic and Clinical Trials Unit, Department of Mental Health Sciences, Royal Free and University College Medical School, London, UK
    Int J Geriatr Psychiatry 22:343-9. 2007
    ..The hypothesis was that donepezil would reduce the incidence of postoperative delirium...
  8. doi request reprint Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial
    Lars Lannfelt
    Department of Public Health and Geriatrics, Uppsala University Hospital, Uppsala, Sweden
    Lancet Neurol 7:779-86. 2008
    ..Strong preclinical efficacy data and the completion of early, clinical safety studies have preceded this phase IIa study, the aim of which was to assess the effects of PBT2 on safety, efficacy, and biomarkers of AD...
  9. ncbi request reprint Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial
    Craig W Ritchie
    Departments of Pathology, The University of Melbourne, The Mental Health Research Institute of Victoria, Parkville, Victoria, Australia
    Arch Neurol 60:1685-91. 2003
    ..Alzheimer disease (AD) may be caused by the toxic accumulation of beta-amyloid (Abeta)...
  10. ncbi request reprint The incidence of delirium associated with orthopedic surgery: a meta-analytic review
    Angela J Bruce
    Waitemata District Health Board, Auckland, New Zealand
    Int Psychogeriatr 19:197-214. 2007
    ..The aim of this study was to perform a systematic review and meta-analysis of the literature regarding the incidence of delirium following orthopedic surgery...
  11. ncbi request reprint Carer impressions of participation in Alzheimer's disease clinical trials: what are their hopes? And is it worth it?
    Maree Mastwyk
    Mental Health Research Institute, Parkville, Australia
    Int Psychogeriatr 14:39-45. 2002
    ..We aimed to assess why carers seek participation for their relatives in clinical trials of Alzheimer's disease (AD) medications, and to assess carer impressions of the value of trial participation...