M C Richardson

Summary

Affiliation: University of Southampton
Country: UK

Publications

  1. pmc Rearrangement of extracellular matrix during cluster formation by human luteinising granulosa cells in culture
    M C Richardson
    Obstetrics and Gynaecology, School of Medicine, University of Southampton, Princess Anne Hospital, UK
    J Anat 196:243-8. 2000
  2. ncbi request reprint Insulin and human chorionic gonadotropin cause a shift in the balance of sterol regulatory element-binding protein (SREBP) isoforms toward the SREBP-1c isoform in cultures of human granulosa cells
    Malcolm C Richardson
    Developmental Origins of Health and Disease Research Division, University of Southampton, Level F, Princess Anne Hospital, Coxford Road, Southampton SO16 5YA, United Kingdom
    J Clin Endocrinol Metab 90:3738-46. 2005
  3. doi request reprint Stimulation of lactate production in human granulosa cells by metformin and potential involvement of adenosine 5' monophosphate-activated protein kinase
    Malcolm C Richardson
    Developmental Origins of Health and Disease Research Division, Institute of Developmental Sciences, University of Southampton, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, United Kingdom
    J Clin Endocrinol Metab 94:670-7. 2009
  4. ncbi request reprint Effect of gonadotrophin on cell and matrix retention and expression of metalloproteinases and their inhibitor in cultured human granulosa cells modelling corpus luteum function
    K E Aston
    University of Southampton, Princess Anne Hospital, UK
    Mol Hum Reprod 2:26-30. 1996
  5. ncbi request reprint Luteinized human granulosa cells are associated with endogenous basement membrane-like components in culture
    E Alexopoulos
    Department of Obstetrics and Gynaecology, University of Southampton, Princess Anne Hospital, Coxford Road, Southampton SO16 5YA, UK
    Mol Hum Reprod 6:324-30. 2000
  6. ncbi request reprint Progesterone inhibits insulin-like growth factor binding protein-1 (IGFBP-1) production by explants of the Fallopian tube
    S Davies
    Maternal, Fetal and Neonatal Physiology, Developmental Origins of Health and Disease Division, University of Southampton, Level F 815, Princess Anne Hospital, Coxford Road, Southampton SO16 5YA, UK
    Mol Hum Reprod 10:935-9. 2004
  7. ncbi request reprint Suppression of matrix metalloproteinase production by hCG in cultures of human luteinized granulosa cells as a model for gonadotrophin-induced luteal rescue
    A Stamouli
    Obstetrics and Gynaecology, University of Southampton, UK
    J Reprod Fertil 107:235-9. 1996

Collaborators

Detail Information

Publications7

  1. pmc Rearrangement of extracellular matrix during cluster formation by human luteinising granulosa cells in culture
    M C Richardson
    Obstetrics and Gynaecology, School of Medicine, University of Southampton, Princess Anne Hospital, UK
    J Anat 196:243-8. 2000
    ..Results suggest the potential for active rearrangement of matrix by granulosa-derived cells during corpus luteum development...
  2. ncbi request reprint Insulin and human chorionic gonadotropin cause a shift in the balance of sterol regulatory element-binding protein (SREBP) isoforms toward the SREBP-1c isoform in cultures of human granulosa cells
    Malcolm C Richardson
    Developmental Origins of Health and Disease Research Division, University of Southampton, Level F, Princess Anne Hospital, Coxford Road, Southampton SO16 5YA, United Kingdom
    J Clin Endocrinol Metab 90:3738-46. 2005
    ..We suggest that high circulating insulin, associated with clinically defined insulin resistance, may up-regulate SREBP-1c expression in the ovary...
  3. doi request reprint Stimulation of lactate production in human granulosa cells by metformin and potential involvement of adenosine 5' monophosphate-activated protein kinase
    Malcolm C Richardson
    Developmental Origins of Health and Disease Research Division, Institute of Developmental Sciences, University of Southampton, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, United Kingdom
    J Clin Endocrinol Metab 94:670-7. 2009
    ..Production of 3-carbon units (as lactate) by granulosa cells (GCs) is important in follicular and oocyte development and may be modulated by metformin...
  4. ncbi request reprint Effect of gonadotrophin on cell and matrix retention and expression of metalloproteinases and their inhibitor in cultured human granulosa cells modelling corpus luteum function
    K E Aston
    University of Southampton, Princess Anne Hospital, UK
    Mol Hum Reprod 2:26-30. 1996
    ..We speculate that stabilization of the ECM may be an important aspect of HCG action in the corpus luteum...
  5. ncbi request reprint Luteinized human granulosa cells are associated with endogenous basement membrane-like components in culture
    E Alexopoulos
    Department of Obstetrics and Gynaecology, University of Southampton, Princess Anne Hospital, Coxford Road, Southampton SO16 5YA, UK
    Mol Hum Reprod 6:324-30. 2000
    ..To conclude, luteinization and maintenance of the GC-derived layer of the corpus luteum is likely to involve deposition and conservation of pericellular ECM components...
  6. ncbi request reprint Progesterone inhibits insulin-like growth factor binding protein-1 (IGFBP-1) production by explants of the Fallopian tube
    S Davies
    Maternal, Fetal and Neonatal Physiology, Developmental Origins of Health and Disease Division, University of Southampton, Level F 815, Princess Anne Hospital, Coxford Road, Southampton SO16 5YA, UK
    Mol Hum Reprod 10:935-9. 2004
    ..We suggest that progesterone might, therefore, play a role in controlling the bioavailability of IGFs to the embryo during early development within the Fallopian tube...
  7. ncbi request reprint Suppression of matrix metalloproteinase production by hCG in cultures of human luteinized granulosa cells as a model for gonadotrophin-induced luteal rescue
    A Stamouli
    Obstetrics and Gynaecology, University of Southampton, UK
    J Reprod Fertil 107:235-9. 1996
    ..Our results provide further evidence for the hypothesis that the rescue of the corpus luteum in early pregnancy involves the maintenance of cellular function through the stabilization of the extracellular matrix...