Ciaran Richardson

Summary

Affiliation: University of Dundee
Country: UK

Publications

  1. Richardson C, Alessi D. The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway. J Cell Sci. 2008;121:3293-304 pubmed publisher
    ..We also discuss unresolved and controversial questions in this field of research. ..
  2. Richardson C, Rafiqi F, Karlsson H, Moleleki N, Vandewalle A, Campbell D, et al. Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1. J Cell Sci. 2008;121:675-84 pubmed publisher
    ..They also suggest a mechanism by which increased WNK1 overexpression could lead to hypertension and that inhibitors of SPAK/OSR1 might be of use in reducing blood pressure by suppressing phosphorylation and hence activity of NCC. ..
  3. Richardson C, Sakamoto K, de los Heros P, Deak M, Campbell D, Prescott A, et al. Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways. J Cell Sci. 2011;124:789-800 pubmed publisher