Antonella Riccio

Summary

Affiliation: University College London
Country: UK

Publications

  1. pmc Binding of TFIIIC to sine elements controls the relocation of activity-dependent neuronal genes to transcription factories
    Luca Crepaldi
    MRC Laboratory for Molecular and Cell Biology, University College London, London, United Kingdom
    PLoS Genet 9:e1003699. 2013
  2. doi New endogenous regulators of class I histone deacetylases
    Antonella Riccio
    MRC Laboratory for Molecular and Cell Biology and Department of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK
    Sci Signal 3:pe1. 2010
  3. ncbi A nitric oxide signaling pathway controls CREB-mediated gene expression in neurons
    Antonella Riccio
    Howard Hughes Medical Institute, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21201, USA
    Mol Cell 21:283-94. 2006
  4. doi Dynamic epigenetic regulation in neurons: enzymes, stimuli and signaling pathways
    Antonella Riccio
    Medical Research Council Laboratory for Molecular and Cell Biology and Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK
    Nat Neurosci 13:1330-7. 2010
  5. doi S-Nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons
    Alexi Nott
    MRC Laboratory for Molecular and Cell Biology, and Department of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK
    Nature 455:411-5. 2008
  6. ncbi Chromatin learns to behave
    Luca Crepaldi
    Department of Neuroscience, Physiology and Pharmacology, University College London, UK
    Epigenetics 4:23-6. 2009
  7. pmc S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migration
    Alexi Nott
    Medical Research Council Laboratory for Molecular Cell Biology, University College London, London, WC1E 6BT, United Kingdom
    Proc Natl Acad Sci U S A 110:3113-8. 2013
  8. ncbi Nitric oxide-mediated epigenetic mechanisms in developing neurons
    Alexi Nott
    MRC Laboratory for Molecular and Cell Biology, and Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK
    Cell Cycle 8:725-30. 2009
  9. pmc Inositol pyrophosphates regulate JMJD2C-dependent histone demethylation
    Adam Burton
    Medical Research Council Cell Biology Unit and Department of Cell and Developmental Biology, Medical Research Council Laboratory for Molecular Cell Biology, and Department of Neuroscience, Physiology, and Pharmacology, University College London, London WC1E 6BT, United Kingdom
    Proc Natl Acad Sci U S A 110:18970-5. 2013
  10. doi An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons
    Catia Andreassi
    Medical Research Council Laboratory for Molecular and Cell Biology, University College London, London, UK
    Nat Neurosci 13:291-301. 2010

Collaborators

  • Adolfo Saiardi
  • Marten P Smidt
  • R Jeroen Pasterkamp
  • Christian Muchardt
  • Sonia Cohen
  • Solomon H Snyder
  • Ted Dawson
  • Alexi Nott
  • Luca Crepaldi
  • Catia Andreassi
  • Adam Burton
  • Omar Loss
  • Barbara Bedogni
  • Bonnie E Lonze
  • Alessandro Coatti
  • Bart C Jongbloets
  • Cristina Azevedo
  • Piotr Sirko
  • Justyna Nitarska
  • Cristina Policarpi
  • William T Sherlock
  • Jesse V Veenvliet
  • Thomas A Down
  • Stephan Schacke
  • Alwin A H A Derijck
  • Chun Ting Wu
  • Serena Devita
  • Carola Zimmermann
  • Salvatore Fusco
  • Richard Mitter
  • Serena De Vita
  • P Marc Watson
  • James D Robinson
  • Renata Colavitti
  • Tommaso Galeotti
  • Mike Murphy
  • Silvia Borrello
  • Robin Smith
  • Giovambattista Pani
  • Maria Luisa Eboli
  • David D Ginty

Detail Information

Publications14

  1. pmc Binding of TFIIIC to sine elements controls the relocation of activity-dependent neuronal genes to transcription factories
    Luca Crepaldi
    MRC Laboratory for Molecular and Cell Biology, University College London, London, United Kingdom
    PLoS Genet 9:e1003699. 2013
    ..They also suggest that TFIIIC may regulate the rearrangement of nuclear architecture, allowing the coordinated expression of activity-dependent neuronal genes. ..
  2. doi New endogenous regulators of class I histone deacetylases
    Antonella Riccio
    MRC Laboratory for Molecular and Cell Biology and Department of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK
    Sci Signal 3:pe1. 2010
    ..The discovery of endogenous molecules that regulate HDAC activity in vivo has implications for the development of new therapeutic approaches for a host of human diseases, including cancer and neurodegenerative disorders...
  3. ncbi A nitric oxide signaling pathway controls CREB-mediated gene expression in neurons
    Antonella Riccio
    Howard Hughes Medical Institute, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21201, USA
    Mol Cell 21:283-94. 2006
    ..Thus, in conjunction with CREB phosphorylation, the NO pathway controls CREB-DNA binding and CRE-mediated gene expression...
  4. doi Dynamic epigenetic regulation in neurons: enzymes, stimuli and signaling pathways
    Antonella Riccio
    Medical Research Council Laboratory for Molecular and Cell Biology and Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK
    Nat Neurosci 13:1330-7. 2010
    ..I also summarize additional mechanisms that induce chromatin remodeling events by combinatorial assembly of multiprotein complexes on neuronal gene promoters...
  5. doi S-Nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons
    Alexi Nott
    MRC Laboratory for Molecular and Cell Biology, and Department of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK
    Nature 455:411-5. 2008
    ..Thus, by stimulating NO production and S-nitrosylation of HDAC2, neurotrophic factors promote chromatin remodelling and the activation of genes that are associated with neuronal development...
  6. ncbi Chromatin learns to behave
    Luca Crepaldi
    Department of Neuroscience, Physiology and Pharmacology, University College London, UK
    Epigenetics 4:23-6. 2009
    ....
  7. pmc S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migration
    Alexi Nott
    Medical Research Council Laboratory for Molecular Cell Biology, University College London, London, WC1E 6BT, United Kingdom
    Proc Natl Acad Sci U S A 110:3113-8. 2013
    ..Our study identifies NO and HDAC2 nitrosylation as part of a signaling pathway that regulates cortical development and the expression of Brm in neurons...
  8. ncbi Nitric oxide-mediated epigenetic mechanisms in developing neurons
    Alexi Nott
    MRC Laboratory for Molecular and Cell Biology, and Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK
    Cell Cycle 8:725-30. 2009
    ..Histone deacetylases (HDACs) are the first identified intranuclear targets of NO, but, due to its highly diffusible nature, it is likely that many other nuclear factors are directly regulated by NO...
  9. pmc Inositol pyrophosphates regulate JMJD2C-dependent histone demethylation
    Adam Burton
    Medical Research Council Cell Biology Unit and Department of Cell and Developmental Biology, Medical Research Council Laboratory for Molecular Cell Biology, and Department of Neuroscience, Physiology, and Pharmacology, University College London, London WC1E 6BT, United Kingdom
    Proc Natl Acad Sci U S A 110:18970-5. 2013
    ..Importantly, these effects lead to changes in JMJD2C-target gene transcription. Our findings demonstrate that inositol pyrophosphate signaling influences nuclear functions by regulating histone modifications. ..
  10. doi An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons
    Catia Andreassi
    Medical Research Council Laboratory for Molecular and Cell Biology, University College London, London, UK
    Nat Neurosci 13:291-301. 2010
    ..These results provide insights into mRNA transport in axons and reveal a new NGF-responsive localization element that directs the targeting and local translation of an axonal transcript...
  11. ncbi Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB
    Bonnie E Lonze
    Department of Neuroscience, Howard Hughes Medical Institute, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Neuron 34:371-85. 2002
    ..Thus, during their period of neurotrophin dependency, peripheral neurons require CREB-mediated gene expression for both survival and growth in vivo...
  12. pmc Modulation of inositol polyphosphate levels regulates neuronal differentiation
    Omar Loss
    Cell Biology Unit and Laboratory for Molecular Cell Biology, Medical Research Council, University College London, London WC1E 6BT, United Kingdom Department of Cell and Developmental Biology, University College London, London WC1E 6BT, United Kingdom Department of Neuroscience, University College London, London WC1E 6BT, United Kingdom
    Mol Biol Cell 24:2981-9. 2013
    ..Therefore maintaining appropriate intracellular levels of inositol polyphosphates is necessary for neuronal survival and differentiation...
  13. ncbi Redox regulation of cAMP-responsive element-binding protein and induction of manganous superoxide dismutase in nerve growth factor-dependent cell survival
    Barbara Bedogni
    Institute of General Pathology, Catholic University Medical School, 00168 Rome, Italy
    J Biol Chem 278:16510-9. 2003
    ....
  14. ncbi What a privilege to reside at the synapse: NMDA receptor signaling to CREB
    Antonella Riccio
    Nat Neurosci 5:389-90. 2002