Research Topics
Genomes and Genes | Antonella RiccioSummaryAffiliation: University College London Country: UK Publications
| Collaborators
|
Detail Information
Publications
Dynamic epigenetic regulation in neurons: enzymes, stimuli and signaling pathwaysAntonella Riccio
Medical Research Council Laboratory for Molecular and Cell Biology and Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK
Nat Neurosci 13:1330-7. 2010..I also summarize additional mechanisms that induce chromatin remodeling events by combinatorial assembly of multiprotein complexes on neuronal gene promoters...
A nitric oxide signaling pathway controls CREB-mediated gene expression in neuronsAntonella Riccio
Howard Hughes Medical Institute, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21201, USA
Mol Cell 21:283-94. 2006..Thus, in conjunction with CREB phosphorylation, the NO pathway controls CREB-DNA binding and CRE-mediated gene expression...
New endogenous regulators of class I histone deacetylasesAntonella Riccio
MRC Laboratory for Molecular and Cell Biology and Department of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK
Sci Signal 3:pe1. 2010..The discovery of endogenous molecules that regulate HDAC activity in vivo has implications for the development of new therapeutic approaches for a host of human diseases, including cancer and neurodegenerative disorders...
Chromatin learns to behaveLuca Crepaldi
Department of Neuroscience, Physiology and Pharmacology, University College London, UK
Epigenetics 4:23-6. 2009....
S-Nitrosylation of histone deacetylase 2 induces chromatin remodelling in neuronsAlexi Nott
MRC Laboratory for Molecular and Cell Biology, and Department of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, UK
Nature 455:411-5. 2008..Thus, by stimulating NO production and S-nitrosylation of HDAC2, neurotrophic factors promote chromatin remodelling and the activation of genes that are associated with neuronal development...
Nitric oxide-mediated epigenetic mechanisms in developing neuronsAlexi Nott
MRC Laboratory for Molecular and Cell Biology, and Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK
Cell Cycle 8:725-30. 2009..Histone deacetylases (HDACs) are the first identified intranuclear targets of NO, but, due to its highly diffusible nature, it is likely that many other nuclear factors are directly regulated by NO...
Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREBBonnie E Lonze
Department of Neuroscience, Howard Hughes Medical Institute, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Neuron 34:371-85. 2002..Thus, during their period of neurotrophin dependency, peripheral neurons require CREB-mediated gene expression for both survival and growth in vivo...
An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axonsCatia Andreassi
Medical Research Council Laboratory for Molecular and Cell Biology, University College London, London, UK
Nat Neurosci 13:291-301. 2010..These results provide insights into mRNA transport in axons and reveal a new NGF-responsive localization element that directs the targeting and local translation of an axonal transcript...
S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migrationAlexi Nott
Medical Research Council Laboratory for Molecular Cell Biology, University College London, London, WC1E 6BT, United Kingdom
Proc Natl Acad Sci U S A 110:3113-8. 2013..Our study identifies NO and HDAC2 nitrosylation as part of a signaling pathway that regulates cortical development and the expression of Brm in neurons...
Redox regulation of cAMP-responsive element-binding protein and induction of manganous superoxide dismutase in nerve growth factor-dependent cell survivalBarbara Bedogni
Institute of General Pathology, Catholic University Medical School, 00168 Rome, Italy
J Biol Chem 278:16510-9. 2003....
What a privilege to reside at the synapse: NMDA receptor signaling to CREBAntonella Riccio
Nat Neurosci 5:389-90. 2002
