Andrew G Renwick

Summary

Affiliation: University of Southampton
Country: UK

Publications

  1. ncbi request reprint The intake of intense sweeteners - an update review
    Andrew G Renwick
    School of Medicine, University of Southampton, Southampton, UK
    Food Addit Contam 23:327-38. 2006
  2. doi request reprint Risk assessment of micronutrients
    A G Renwick
    School of Medicine, Faculty of Medicine, Health and Life Sciences, University of Southampton, Southampton SO16 7PX, UK
    Toxicol Lett 180:123-30. 2008
  3. ncbi request reprint Duration of intake above the ADI/TDI in relation to toxicodynamics and toxicokinetics
    A G Renwick
    Clinical Pharmacology Group, University of Southampton, United Kingdom
    Regul Toxicol Pharmacol 30:S69-78. 1999
  4. doi request reprint The use of a sweetener substitution method to predict dietary exposures for the intense sweetener rebaudioside A
    A G Renwick
    School of Medicine, University of Southampton, Boldrewood Campus, Bassett Crescent East, Southampton SO16 7PX, UK
    Food Chem Toxicol 46:S61-9. 2008
  5. ncbi request reprint First European conference on aspartame: putting safety and benefits into perspective. Synopsis of presentations and conclusions
    A G Renwick
    School of Medicine, University of Southampton, Bassett Crescent East, Southampton SO16 7PX, UK
    Food Chem Toxicol 45:1308-13. 2007
  6. ncbi request reprint Establishing the upper end of the range of adequate and safe intakes for amino acids: a toxicologist's viewpoint
    Andrew G Renwick
    Clinical Pharmacology Group, Allergy and Inflammatory Sciences Research Division, School of Medicine, University of Southampton, Southampton, UK SO16 7PX
    J Nutr 134:1617S-1624S; discussion 1630S-1632S, 1667S-1672S. 2004
  7. ncbi request reprint The metabolism of cyclamate to cyclohexylamine in humans during long-term administration
    A G Renwick
    Clinical Pharmacology Group, Allergy and Inflammation Research Division, School of Medicine, University of Southampton, Bassett Crescent East, Southampton SO16 7PX, UK
    Toxicol Appl Pharmacol 196:367-80. 2004
  8. ncbi request reprint Toxicology databases and the concept of thresholds of toxicological concern as used by the JECFA for the safety evaluation of flavouring agents
    A G Renwick
    Clinical Pharmacology Group, Allergy and Inflammatory Sciences Research Division, School of Medicine, University of Southampton, Biomedical Sciences Building, Bassett Crescent East, Southampton SO16 7PX, UK
    Toxicol Lett 149:223-34. 2004
  9. ncbi request reprint The use of surrogate endpoints to assess potential toxicity in humans
    A G Renwick
    Clinical Pharmacology Group, University of Southampton, Biomedical Sciences Building, Bassett Crescent East, SO16 7PX, Southampton, UK
    Toxicol Lett 120:97-110. 2001
  10. ncbi request reprint Pesticide residue analysis and its relationship to hazard characterisation (ADI/ARfD) and intake estimations (NEDI/NESTI)
    Andrew G Renwick
    Clinical Pharmacology Group, University of Southampton, Biomedical Sciences Building, Bassett Crescent East, Southampton SO16 7PX, UK
    Pest Manag Sci 58:1073-82. 2002

Detail Information

Publications17

  1. ncbi request reprint The intake of intense sweeteners - an update review
    Andrew G Renwick
    School of Medicine, University of Southampton, Southampton, UK
    Food Addit Contam 23:327-38. 2006
    ..This sub-group was identified as having high intakes of cyclamate in 1999, and recent studies have not generated reliable intake data to address this possibility...
  2. doi request reprint Risk assessment of micronutrients
    A G Renwick
    School of Medicine, Faculty of Medicine, Health and Life Sciences, University of Southampton, Southampton SO16 7PX, UK
    Toxicol Lett 180:123-30. 2008
    ..Risk-benefit approaches have been developed recently that balance the risk of toxicity against the risk of deficiency, and offer the potential for more scientifically based methods...
  3. ncbi request reprint Duration of intake above the ADI/TDI in relation to toxicodynamics and toxicokinetics
    A G Renwick
    Clinical Pharmacology Group, University of Southampton, United Kingdom
    Regul Toxicol Pharmacol 30:S69-78. 1999
    ..The effect on the body load of a short period of intake above the ADI is inversely proportional to the half-life of the chemical...
  4. doi request reprint The use of a sweetener substitution method to predict dietary exposures for the intense sweetener rebaudioside A
    A G Renwick
    School of Medicine, University of Southampton, Boldrewood Campus, Bassett Crescent East, Southampton SO16 7PX, UK
    Food Chem Toxicol 46:S61-9. 2008
    ..In consequence, this analysis shows that the intakes of rebaudioside A would not exceed the JECFA temporary ADI set for steviol glycosides...
  5. ncbi request reprint First European conference on aspartame: putting safety and benefits into perspective. Synopsis of presentations and conclusions
    A G Renwick
    School of Medicine, University of Southampton, Bassett Crescent East, Southampton SO16 7PX, UK
    Food Chem Toxicol 45:1308-13. 2007
    ..It was recognised that risk assessment alone gave an unbalanced impression to regulators and consumers, and that in the future quantitative risk-benefit analyses should be able to provide more comprehensive advice...
  6. ncbi request reprint Establishing the upper end of the range of adequate and safe intakes for amino acids: a toxicologist's viewpoint
    Andrew G Renwick
    Clinical Pharmacology Group, Allergy and Inflammatory Sciences Research Division, School of Medicine, University of Southampton, Southampton, UK SO16 7PX
    J Nutr 134:1617S-1624S; discussion 1630S-1632S, 1667S-1672S. 2004
    ..A population-distribution approach could be used to define the magnitude of any risk at intake levels above the guidance value...
  7. ncbi request reprint The metabolism of cyclamate to cyclohexylamine in humans during long-term administration
    A G Renwick
    Clinical Pharmacology Group, Allergy and Inflammation Research Division, School of Medicine, University of Southampton, Bassett Crescent East, Southampton SO16 7PX, UK
    Toxicol Appl Pharmacol 196:367-80. 2004
    ..The results of this metabolism study support an acceptable daily intake (ADI) of 0-11 mg/kg body weight per day...
  8. ncbi request reprint Toxicology databases and the concept of thresholds of toxicological concern as used by the JECFA for the safety evaluation of flavouring agents
    A G Renwick
    Clinical Pharmacology Group, Allergy and Inflammatory Sciences Research Division, School of Medicine, University of Southampton, Biomedical Sciences Building, Bassett Crescent East, Southampton SO16 7PX, UK
    Toxicol Lett 149:223-34. 2004
    ..An additional threshold of 1.5 microg per day, derived from doses of investigated chemicals giving a calculated cancer risk of one in a million, is applied when appropriate toxicity data are not available...
  9. ncbi request reprint The use of surrogate endpoints to assess potential toxicity in humans
    A G Renwick
    Clinical Pharmacology Group, University of Southampton, Biomedical Sciences Building, Bassett Crescent East, SO16 7PX, Southampton, UK
    Toxicol Lett 120:97-110. 2001
    ....
  10. ncbi request reprint Pesticide residue analysis and its relationship to hazard characterisation (ADI/ARfD) and intake estimations (NEDI/NESTI)
    Andrew G Renwick
    Clinical Pharmacology Group, University of Southampton, Biomedical Sciences Building, Bassett Crescent East, Southampton SO16 7PX, UK
    Pest Manag Sci 58:1073-82. 2002
    ..Other causes of public concern, such as the presence of multiple residues, are currently under investigation...
  11. ncbi request reprint The safety testing of amino acids
    Andrew G Renwick
    Clinical Pharmacology Group, University of Southampton, Biomedical Sciences Building, Southampton SO16 7PX, UK
    J Nutr 133:2031S-2033S. 2003
    ....
  12. ncbi request reprint Risk characterisation of chemicals in food
    A G Renwick
    Clinical Pharmacology Group, Allergy and Inflammatory Sciences Research Division, School of Medicine, University of Southampton, Biomedical Sciences Building, Bassett Crescent East, Southampton SO16 7PX, UK
    Toxicol Lett 149:163-76. 2004
    ..A population distribution model is proposed that is applicable to estimate the risk associated with exposure to compounds producing threshold effects...
  13. doi request reprint Sweet-taste receptors, low-energy sweeteners, glucose absorption and insulin release
    Andrew G Renwick
    School of Medicine, University of Southampton, Southampton SO17 1BJ, UK
    Br J Nutr 104:1415-20. 2010
    ..Thus, the data from extensive in vivo studies in human subjects show that low-energy sweeteners do not have any of the adverse effects predicted by in vitro, in situ or knockout studies in animals...
  14. doi request reprint Minimising the population risk of micronutrient deficiency and over-consumption: a new approach using selenium as an example
    Andrew G Renwick
    School of Medicine, University of Southampton, Southampton, SO16 7PX, UK
    Eur J Nutr 47:17-25. 2008
    ....
  15. ncbi request reprint The Fourth Workshop on the Assessment of Adequate Intake of Dietary Amino Acids: general discussion of session 3 and overall workshop discussion
    Andrew G Renwick
    School of Medicine, University of Southampton, Bassett Crescent East, UK
    J Nutr 135:1602S-6S. 2005
  16. ncbi request reprint The 5th workshop on the assessment of adequate intake of dietary amino acids: general discussion 2
    Ian C Munro
    Cantox Health Sciences International, Missisauga, Ontario 15N 2X7, Canada
    J Nutr 136:1755S-1757S. 2006
  17. ncbi request reprint Aspartame: review of safety
    Harriett H Butchko
    Medical and Scientific Affairs, The NutraSweet Company, Mt Prospect, Illinois 60056, USA
    Regul Toxicol Pharmacol 35:S1-93. 2002
    ....