Jonathan L Rees

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. pmc Melanoma: what are the gaps in our knowledge
    Jonathan L Rees
    University of Edinburgh, Edinburgh, United Kingdom
    PLoS Med 5:e122. 2008
  2. ncbi request reprint Genetics of hair and skin color
    Jonathan L Rees
    Systems Group, Dermatology, University of Edinburgh, Lauriston Buildings, Lauriston Place, Edinburgh, EH3 9YW, United Kingdom
    Annu Rev Genet 37:67-90. 2003
  3. ncbi request reprint The time course of photoadaptation and pigmentation studied using a novel method to distinguish pigmentation from erythema
    Carol Oh
    Systems Group, Dermatology, University of Edinburgh, Edinburgh, UK
    J Invest Dermatol 123:965-72. 2004
  4. ncbi request reprint Physiological variation in the erythemal response to ultraviolet radiation and photoadaptation
    Karen Waterston
    Systems Group, Dermatology, The University of Edinburgh, Edinburgh, Scotland, UK
    J Invest Dermatol 123:958-64. 2004
  5. ncbi request reprint Quantitative measures of the effect of the melanocortin 1 receptor on human pigmentary status
    Lisa Naysmith
    Systems Group, Dermatology, University of Edinburgh, Edinburgh, UK
    J Invest Dermatol 122:423-8. 2004
  6. pmc The genetics of sun sensitivity in humans
    Jonathan L Rees
    Systems Group, Dermatology, University of Edinburgh, Edinburgh, United Kingdom
    Am J Hum Genet 75:739-51. 2004
  7. doi request reprint Teaching and learning in dermatology: from Gutenberg to Zuckerberg via way of Von Hebra
    Jonathan L Rees
    University of Edinburgh, Lauriston Building, Edinburgh, United Kingdom
    Acta Derm Venereol 93:13-22. 2013
  8. doi request reprint Variation in epidermal morphology in human skin at different body sites as measured by reflectance confocal microscopy
    Karen Robertson
    Dermatology, University of Edinburgh, Edinburgh, UK
    Acta Derm Venereol 90:368-73. 2010
  9. ncbi request reprint Trials, evidence, and the management of patients with psoriasis
    Jonathan L Rees
    University of Edinburgh, United Kingdom
    J Am Acad Dermatol 48:135-43. 2003
  10. ncbi request reprint Red hair--a desirable mutation?
    Thomas Ha
    Department of Dermatology, University of Edinburgh, Edinburgh, UK
    J Cosmet Dermatol 1:62-5. 2002

Collaborators

Detail Information

Publications27

  1. pmc Melanoma: what are the gaps in our knowledge
    Jonathan L Rees
    University of Edinburgh, Edinburgh, United Kingdom
    PLoS Med 5:e122. 2008
  2. ncbi request reprint Genetics of hair and skin color
    Jonathan L Rees
    Systems Group, Dermatology, University of Edinburgh, Lauriston Buildings, Lauriston Place, Edinburgh, EH3 9YW, United Kingdom
    Annu Rev Genet 37:67-90. 2003
    ..It is argued that given advances in model systems, increases in technical facility, and the lower cost of genotype assessment, the lack of standardized phenotype assessment is now a major limit on advance...
  3. ncbi request reprint The time course of photoadaptation and pigmentation studied using a novel method to distinguish pigmentation from erythema
    Carol Oh
    Systems Group, Dermatology, University of Edinburgh, Edinburgh, UK
    J Invest Dermatol 123:965-72. 2004
    ..For comparison we also document overall photoadaptation and relate changes in pigmentation to the overall changes in photoadaptation...
  4. ncbi request reprint Physiological variation in the erythemal response to ultraviolet radiation and photoadaptation
    Karen Waterston
    Systems Group, Dermatology, The University of Edinburgh, Edinburgh, Scotland, UK
    J Invest Dermatol 123:958-64. 2004
    ....
  5. ncbi request reprint Quantitative measures of the effect of the melanocortin 1 receptor on human pigmentary status
    Lisa Naysmith
    Systems Group, Dermatology, University of Edinburgh, Edinburgh, UK
    J Invest Dermatol 122:423-8. 2004
    ....
  6. pmc The genetics of sun sensitivity in humans
    Jonathan L Rees
    Systems Group, Dermatology, University of Edinburgh, Edinburgh, United Kingdom
    Am J Hum Genet 75:739-51. 2004
    ..Thus, a single locus, identified within a Mendelian framework, can contribute significantly to human pigmentary variation...
  7. doi request reprint Teaching and learning in dermatology: from Gutenberg to Zuckerberg via way of Von Hebra
    Jonathan L Rees
    University of Edinburgh, Lauriston Building, Edinburgh, United Kingdom
    Acta Derm Venereol 93:13-22. 2013
    ..After summarising some of the core principles underpinning successful learning, and modern theories of medical expertise, I critically discuss some of the ways the Web and allied technologies might enhance the learning of dermatology...
  8. doi request reprint Variation in epidermal morphology in human skin at different body sites as measured by reflectance confocal microscopy
    Karen Robertson
    Dermatology, University of Edinburgh, Edinburgh, UK
    Acta Derm Venereol 90:368-73. 2010
    ..This fine-scale variation limits the ease of use of reflectance confocal microscopy for quantitative studies of the epidermis and stratum corneum...
  9. ncbi request reprint Trials, evidence, and the management of patients with psoriasis
    Jonathan L Rees
    University of Edinburgh, United Kingdom
    J Am Acad Dermatol 48:135-43. 2003
  10. ncbi request reprint Red hair--a desirable mutation?
    Thomas Ha
    Department of Dermatology, University of Edinburgh, Edinburgh, UK
    J Cosmet Dermatol 1:62-5. 2002
    ..This paper reviews the path of discovery of the MC1R in control of animal coat colour, the subsequent role of MC1R in human physiology and possibly wider role of MC1R in human skin carcinogenesis and human development through history...
  11. doi request reprint Vexed by red-headed conundrums
    Jonathan L Rees
    Department of Dermatology, University of Edinburgh, Edinburgh, UK
    J Invest Dermatol 130:1771-3. 2010
    ..describe their use of mouse transgenics to demonstrate that the MC1R signaling pathway influences cancer risk via mechanisms in addition to pigmentation...
  12. ncbi request reprint Casting light on evidence
    Jonathan L Rees
    Department of Dermatology, University of Edinburgh, Edinburgh, United Kingdom
    J Invest Dermatol 127:1570-1. 2007
    ..Nor should they. In a new RCT, Kirke and colleagues have compared the therapeutic effects of different types of UVB radiation on clearance of psoriasis. Their study is unlikely to be the last word on this topic...
  13. pmc Dermatology undergraduate skin cancer training: a disconnect between recommendations, clinical exposure and competence
    R Benjamin Aldridge
    Department of Dermatology, University of Edinburgh, Level 1 Lauriston Building, Lauriston Place, Edinburgh, EH3 9HA, UK
    BMC Med Educ 12:27. 2012
    ..We set out to determine students' competence at skin lesion diagnosis and to quantify their clinical exposure to examples of such lesions during their dermatology attachment...
  14. doi request reprint Understanding the evolution of human pigmentation: recent contributions from population genetics
    Jonathan L Rees
    Department of Dermatology, University of Edinburgh, Edinburgh, UK
    J Invest Dermatol 132:846-53. 2012
    ..Future larger studies are likely to provide more details of this process and may provide evidence for exactly which mechanistic pathways have mediated selection...
  15. ncbi request reprint Measurement of itch using actigraphy in pediatric and adult populations
    Carol Bringhurst
    Systems Group, Department of Dermatology, The University of Edinburgh, Edinburgh, United Kingdom
    J Am Acad Dermatol 51:893-8. 2004
    ..Our results support the use of objective measures of scratch in the assessment of disease activity, and suggest that the relation between subjective and objective measures of disease severity may not be straightforward...
  16. doi request reprint How robust are the Dermatology Life Quality Index and other self-reported subjective symptom scores when exposed to a range of experimental biases?
    Caroline S Murray
    Department of Dermatology, Room 4 018, First Floor, The Lauriston Building, Lauriston Place, Edinburgh, EH3 9HA, United Kingdom
    Acta Derm Venereol 90:34-8. 2010
    ..ADLQI median scores were higher (ADLQI 8.25, DLQI 6.75), but not significantly so (p = 0.47). We have been unable to demonstrate any effects of the biases studied, but the statistical power of our study is modest...
  17. ncbi request reprint The relationship between constitutive pigmentation and sensitivity to ultraviolet radiation induced erythema is dose-dependent
    Thomas Ha
    Department of Dermatology, University of Edinburgh, Edinburgh, UK
    Pigment Cell Res 16:477-9. 2003
    ..14 and 0.17 respectively. The proportion of variation explained is also greater at higher UVR challenge doses. Studies relating UVR sensitivity and pigmentation need to take account of the dose of UVR administered...
  18. ncbi request reprint Two cultures?
    Jonathan L Rees
    Department of Dermatology, University of Edinburgh, United Kingdom
    J Am Acad Dermatol 46:313-6. 2002
  19. ncbi request reprint Time course of ultraviolet B-induced erythema in people with red hair harbouring homozygous melanocortin 1 receptor mutations
    Thomas K K Ha
    Systems Group, Dermatology, University of Edinburgh, Edinburgh, UK
    Exp Dermatol 12:514-7. 2003
    ..We could detect no consistent differences in ultraviolet radiation-induced erythema between the groups studied. The pharmacological mechanisms underpinning such prolonged inflammatory responses merit further investigation...
  20. ncbi request reprint Ultraviolet radiation sensitivity in vitiligo and adjacent normal skin
    Carol Oh
    Acta Derm Venereol 86:380. 2006
  21. ncbi request reprint Pharmacological characterization of loss of function mutations of the human melanocortin 1 receptor that are associated with red hair
    Aneta Ringholm
    Department of Neuroscience, Division of Pharmacology, Uppsala University, Uppsala, Sweden
    J Invest Dermatol 123:917-23. 2004
    ..The results provide important pharmacological characterization of common MC1 receptor variants in various world populations...
  22. ncbi request reprint Variation in skin thickness may explain some of the within-person variation in ultraviolet radiation-induced erythema at different body sites
    Karen Waterston
    J Invest Dermatol 124:1078. 2005
  23. ncbi request reprint The usefulness of 4-amino-3-hydroxyphenylalanine as a specific marker of pheomelanin
    Kazumasa Wakamatsu
    Fujita Health University School of Health Sciences, Toyoake, Aichi, Japan
    Pigment Cell Res 15:225-32. 2002
    ..Thus, we conclude that 'specific AHP' is a more specific marker of pheomelanin than is 'total AHP'...
  24. ncbi request reprint Impact of homozygosity of R151C variant of MC1r in human hair follicle melanocytes
    St├ęphane F Commo
    J Invest Dermatol 128:1319-22. 2008
  25. ncbi request reprint No association between p53 codon 72 polymorphisms and erythemal response
    Claire Manson
    J Invest Dermatol 122:1334-5. 2004
  26. ncbi request reprint The development of an objective method for measuring scratch in children with atopic dermatitis suitable for clinical use
    Kenneth Benjamin
    Systems Group, Department of Dermatology, The University of Edinburgh, Lauriston, UK
    J Am Acad Dermatol 50:33-40. 2004
    ..Accelerometers provide a useful and practical way of assessing scratching at night in the patient's own home and could be used as an objective measure of disease activity both in clinical trials and in everyday clinical practice...
  27. ncbi request reprint Phenotypic expression of melanocortin-1 receptor mutations in Black Jamaicans
    Colin A McKenzie
    Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona, Kingston, Jamaica
    J Invest Dermatol 121:207-8. 2003