P Redgrave

Summary

Affiliation: University of Sheffield
Country: UK

Publications

  1. doi request reprint Functional properties of the basal ganglia's re-entrant loop architecture: selection and reinforcement
    P Redgrave
    Neuroscience Research Unit, Department of Psychology, University of Sheffield, Sheffield S10 2TP, UK
    Neuroscience 198:138-51. 2011
  2. ncbi request reprint The short-latency dopamine signal: a role in discovering novel actions?
    Peter Redgrave
    Neuroscience Research Unit, Department of Psychology, University of Sheffield, Sheffield, S10 2TP, UK
    Nat Rev Neurosci 7:967-75. 2006
  3. pmc Goal-directed and habitual control in the basal ganglia: implications for Parkinson's disease
    Peter Redgrave
    Neuroscience Research Unit, Department of Psychology, University of Sheffield, UK
    Nat Rev Neurosci 11:760-72. 2010
  4. doi request reprint Brainstem interactions with the basal ganglia
    Peter Redgrave
    Department of Psychology, University of Sheffield, Sheffield, S10 2TP, UK
    Parkinsonism Relat Disord 13:S301-5. 2007
  5. ncbi request reprint Nociceptive neurones in rat superior colliculus. II. Effects of lesions to the contralateral descending output pathway on nocifensive behaviours
    P Redgrave
    Department of Psychology, University of Sheffield, UK
    Exp Brain Res 109:197-208. 1996
  6. ncbi request reprint Nociceptive neurones in rat superior colliculus. I. Antidromic activation from the contralateral predorsal bundle
    P Redgrave
    Department of Psychology, University of Sheffield, UK
    Exp Brain Res 109:185-96. 1996
  7. ncbi request reprint What is reinforced by phasic dopamine signals?
    Peter Redgrave
    Department of Psychology, University of Sheffield, Western Bank, Sheffield, S10 2TP, UK
    Brain Res Rev 58:322-39. 2008
  8. pmc Fine detail of neurovascular coupling revealed by spatiotemporal analysis of the hemodynamic response to single whisker stimulation in rat barrel cortex
    J Berwick
    Department of Psychology, University of Sheffield, Sheffield S10 2TN, UK
    J Neurophysiol 99:787-98. 2008
  9. ncbi request reprint Neurovascular coupling investigated with two-dimensional optical imaging spectroscopy in rat whisker barrel cortex
    J Berwick
    Department of Psychology, University of Sheffield, Western Bank, Sheffield S10 2TP, UK
    Eur J Neurosci 22:1655-66. 2005
  10. doi request reprint Negative blood oxygen level dependence in the rat: a model for investigating the role of suppression in neurovascular coupling
    Luke Boorman
    Department of Psychology, University of Sheffield, Sheffield S10 2TN, United Kingdom
    J Neurosci 30:4285-94. 2010

Detail Information

Publications39

  1. doi request reprint Functional properties of the basal ganglia's re-entrant loop architecture: selection and reinforcement
    P Redgrave
    Neuroscience Research Unit, Department of Psychology, University of Sheffield, Sheffield S10 2TP, UK
    Neuroscience 198:138-51. 2011
    ..We suggest that this mechanism may be better suited to ensure the prioritisation of inputs associated with reward...
  2. ncbi request reprint The short-latency dopamine signal: a role in discovering novel actions?
    Peter Redgrave
    Neuroscience Research Unit, Department of Psychology, University of Sheffield, Sheffield, S10 2TP, UK
    Nat Rev Neurosci 7:967-75. 2006
    ....
  3. pmc Goal-directed and habitual control in the basal ganglia: implications for Parkinson's disease
    Peter Redgrave
    Neuroscience Research Unit, Department of Psychology, University of Sheffield, UK
    Nat Rev Neurosci 11:760-72. 2010
    ..Thus, many of their behavioural difficulties may reflect a loss of normal automatic control owing to distorting output signals from habitual control circuits, which impede the expression of goal-directed action...
  4. doi request reprint Brainstem interactions with the basal ganglia
    Peter Redgrave
    Department of Psychology, University of Sheffield, Sheffield, S10 2TP, UK
    Parkinsonism Relat Disord 13:S301-5. 2007
    ..The potential functions of the basal ganglia network are then considered together along with resulting insights that may help our understanding of Parkinson's disease and other basal ganglia-related disorders...
  5. ncbi request reprint Nociceptive neurones in rat superior colliculus. II. Effects of lesions to the contralateral descending output pathway on nocifensive behaviours
    P Redgrave
    Department of Psychology, University of Sheffield, UK
    Exp Brain Res 109:197-208. 1996
    ..These data suggest that, under certain behavioural circumstances, nociceptive information from the SC is integral to the elaboration of orienting and approach movements of the head and mouth elicited by persistent noxious stimuli...
  6. ncbi request reprint Nociceptive neurones in rat superior colliculus. I. Antidromic activation from the contralateral predorsal bundle
    P Redgrave
    Department of Psychology, University of Sheffield, UK
    Exp Brain Res 109:185-96. 1996
    ..Nociceptive neurones could, therefore, effect orientation responses to noxious stimuli via similar output pathways that low-threshold neurones utilize to initiate orientation to innocuous stimuli...
  7. ncbi request reprint What is reinforced by phasic dopamine signals?
    Peter Redgrave
    Department of Psychology, University of Sheffield, Western Bank, Sheffield, S10 2TP, UK
    Brain Res Rev 58:322-39. 2008
    ..Furthermore, DA-promoted repetition of preceding actions/movements should enable the system to converge on those aspects of context and behavioural output that lead to the discovery of novel actions...
  8. pmc Fine detail of neurovascular coupling revealed by spatiotemporal analysis of the hemodynamic response to single whisker stimulation in rat barrel cortex
    J Berwick
    Department of Psychology, University of Sheffield, Sheffield S10 2TN, UK
    J Neurophysiol 99:787-98. 2008
    ..These data confirm hemodynamics are capable of providing accurate "single-condition" maps of neural activity...
  9. ncbi request reprint Neurovascular coupling investigated with two-dimensional optical imaging spectroscopy in rat whisker barrel cortex
    J Berwick
    Department of Psychology, University of Sheffield, Western Bank, Sheffield S10 2TP, UK
    Eur J Neurosci 22:1655-66. 2005
    ..There was also a consistent increase in Hbr from arterial regions after whisker stimulation...
  10. doi request reprint Negative blood oxygen level dependence in the rat: a model for investigating the role of suppression in neurovascular coupling
    Luke Boorman
    Department of Psychology, University of Sheffield, Sheffield S10 2TN, United Kingdom
    J Neurosci 30:4285-94. 2010
    ..Since a similar type of neural suppression in surround regions was associated with a negative BOLD signal, the increased levels of suppression in positive BOLD regions could importantly moderate the size of the observed BOLD response...
  11. ncbi request reprint How visual stimuli activate dopaminergic neurons at short latency
    Eleanor Dommett
    Department of Psychology, University of Sheffield, Sheffield, S10 2TP, UK
    Science 307:1476-9. 2005
    ..As the primary source of visual afferents, the limited processing capacities of the colliculus may constrain the visual information content of phasic DA responses...
  12. ncbi request reprint Nociceptive responses of midbrain dopaminergic neurones are modulated by the superior colliculus in the rat
    V Coizet
    Department of Psychology, University of Sheffield, UK
    Neuroscience 139:1479-93. 2006
    ..However, the superior colliculus is unlikely to be the primary source of nociceptive sensory input to the ventral midbrain...
  13. ncbi request reprint Phasic activation of substantia nigra and the ventral tegmental area by chemical stimulation of the superior colliculus: an electrophysiological investigation in the rat
    Veronique Coizet
    Department of Psychology, University of Sheffield, Sheffield, S10 2TP, UK
    Eur J Neurosci 17:28-40. 2003
    ..These data suggest that the SC is in a position to play an important role in discriminating the appropriate stimulus qualities required to activate DA cells at short latency...
  14. ncbi request reprint A computational model of action selection in the basal ganglia. II. Analysis and simulation of behaviour
    K Gurney
    Department of Psychology, University of Sheffield, Sheffield S10 2TP, UK
    Biol Cybern 84:411-23. 2001
    ..Third, the behaviour of the model as a signal selection mechanism has parallels with some kinds of action selection observed in animals under various levels of dopaminergic modulation...
  15. ncbi request reprint Covariant maturation of nocifensive oral behaviour and c-fos expression in rat superior colliculus
    J G McHaffie
    Department of Psychology, University of Sheffield S10 2TP, UK
    Neuroscience 109:597-607. 2002
    ....
  16. ncbi request reprint Cerebral vasomotion: a 0.1-Hz oscillation in reflected light imaging of neural activity
    J E Mayhew
    Artificial Intelligence Vision Research Unit, University of Sheffield, United Kingdom
    Neuroimage 4:183-93. 1996
    ....
  17. ncbi request reprint Adverse drug effects following oseltamivir mass treatment and prophylaxis in a school outbreak of 2009 pandemic influenza A(H1N1) in June 2009, Sheffield, United Kingdom
    M Strong
    School of Health and Related Research, University of Sheffield, Sheffield, United Kingdom
    Euro Surveill 15:pii/19565. 2010
    ....
  18. ncbi request reprint Nonlinear coupling of neural activity and CBF in rodent barrel cortex
    Myles Jones
    Neural Imaging Research Unit, Department of Psychology, University of Sheffield, Western Bank, Sheffield S10 2TP, UK
    Neuroimage 22:956-65. 2004
    ..These results show that care must be exercised when interpreting imaging data elicited by particularly strong or weak stimuli and that hemodynamic changes may better reflect the input to a region rather than its spiking output...
  19. pmc Collateralization of the tectonigral projection with other major output pathways of superior colliculus in the rat
    Veronique Coizet
    Neuroscience Research Unit, Department of Psychology, University of Sheffield, Sheffield, S10 2TP, UK
    J Comp Neurol 500:1034-49. 2007
    ....
  20. ncbi request reprint A robot model of the basal ganglia: behavior and intrinsic processing
    Tony J Prescott
    Adaptive Behavior Research Group, Department of Psychology, University of Sheffield, Sheffield, Western Bank, South Yorkshire, Sheffield S10 2TN, UK
    Neural Netw 19:31-61. 2006
    ..The model is shown to cast light on recent neurobiological findings concerning behavioral switching and sequencing...
  21. doi request reprint Altered neurovascular coupling during information-processing states
    Myles Jones
    The Centre for Signal Processing in Neuroimaging and Systems Neuroscience, Department of Psychology, University of Sheffield, Western Bank, Sheffield S10 2TP, UK
    Eur J Neurosci 27:2758-72. 2008
    ..These data suggest that there may be differences in stimulus-evoked neural activity and accompanying haemodynamics during different information-processing states...
  22. ncbi request reprint The hemodynamic impulse response to a single neural event
    John Martindale
    Psychology Department, University of Sheffield, Western Bank Sheffield, UK
    J Cereb Blood Flow Metab 23:546-55. 2003
    ..The model provided an excellent fit to the empirical data. The implications of these results for modeling schemes and for physiologic systems coupling neural and hemodynamic activity are discussed...
  23. ncbi request reprint Integration of neural responses originating from different regions of the cortical somatosensory map
    J Berwick
    Department of Psychology, University of Sheffield, Western Bank, Sheffield S10 2TP, UK
    Brain Res 1030:284-93. 2004
    ..Furthermore, the longer latency of the inhibition following stimulation of the contralateral forepaw suggests the possible involvement of extracortical circuitry...
  24. ncbi request reprint A computational model of action selection in the basal ganglia. I. A new functional anatomy
    K Gurney
    Department of Psychology, University of Sheffield, Sheffield S10 2TP, UK
    Biol Cybern 84:401-10. 2001
    ..The model contrasts with the prevailing functional segregation of basal ganglia into 'direct' and 'indirect' pathways...
  25. ncbi request reprint Differential expression of fos-like immunoreactivity in the descending projections of superior colliculus after electrical stimulation in the rat
    S M King
    Department of Psychology, University of Sheffield, UK
    Behav Brain Res 78:131-45. 1996
    ..However, given the total lack of expression in a pathway which is known to be activated, it also provides further evidence that c-fos cannot simply be used as a high resolution neuronal activity marker for mapping functional pathways...
  26. ncbi request reprint Computational models of the basal ganglia: from robots to membranes
    Kevin Gurney
    Adaptive Behaviour Research Group, Department of Psychology, University of Sheffield, Sheffield S10 2TP, UK
    Trends Neurosci 27:453-9. 2004
    ..We identify distinct modelling strategies that can deliver important and complementary insights into the nature of problems the basal ganglia have evolved to solve, and describe methods that are used to solve them...
  27. ncbi request reprint A direct projection from superior colliculus to substantia nigra for detecting salient visual events
    Eliane Comoli
    Department of Psychology, University of Sheffield, Sheffield S10 2TP, UK
    Nat Neurosci 6:974-80. 2003
    ..We conclude that it is within this afferent sensory circuitry that the critical perceptual discriminations that identify stimuli as both unpredicted and biologically salient are made...
  28. ncbi request reprint Hemodynamic response in the unanesthetized rat: intrinsic optical imaging and spectroscopy of the barrel cortex
    Jason Berwick
    Department of Psychology and Artificial Intelligence Vision Research Unit, University of Sheffield, Western Bank, Sheffield, UK
    J Cereb Blood Flow Metab 22:670-9. 2002
    ..This work represents a step in the development of an experimental model that can be used to investigate fundamental neurologic processes in the awake-behaving rodent...
  29. doi request reprint Cortical regulation of dopaminergic neurons: role of the midbrain superior colliculus
    C Bertram
    Department of Psychology, University of Sheffield, Western Bank, Sheffield, United Kingdom and
    J Neurophysiol 111:755-67. 2014
    ..As a consequence, DA neuronal activity reflecting the unexpected occurrence of salient events and that signaling more complex stimulus properties may have a common origin. ..
  30. ncbi request reprint N-methyl D-aspartate (NMDA) evoked changes in blood pressure and heart rate from the rat superior colliculus
    K A Keay
    Department of Psychology, University of Sheffield, U K
    Exp Brain Res 80:148-56. 1990
    ..The question of whether the rostromedial SC might represent an early link in the circuitry responsible for organizing defensive movements and appropriate physiological changes to potentially dangerous overhead stimuli is considered...
  31. ncbi request reprint Testing computational hypotheses of brain systems function: a case study with the basal ganglia
    K N Gurney
    Adaptive Behaviour Research Group, Department of Psychology, University of Sheffield, S10 2TP, UK
    Network 15:263-90. 2004
    ..The realistically constrained models show a selection benefit, while control models show a decrement in selection ability. These results, taken together, provide further validation of our selection hypothesis of basal ganglia function...
  32. pmc Short-latency visual input to the subthalamic nucleus is provided by the midbrain superior colliculus
    Veronique Coizet
    Department of Psychology, University of Sheffield, Sheffield S10 2TP, United Kingdom
    J Neurosci 29:5701-9. 2009
    ....
  33. ncbi request reprint Optical imaging spectroscopy in the unanaesthetised rat
    Chris Martin
    Artificial Intelligence Vision Research Unit, Department of Psychology, University of Sheffield, Western Bank, S10 2TP, Sheffield, UK
    J Neurosci Methods 120:25-34. 2002
    ..This preparation may make possible the investigation of the haemodynamic correlates of a broad range of neurological processes in the awake, behaving rodent...
  34. pmc Empirically inspired simulated electro-mechanical model of the rat mystacial follicle-sinus complex
    Ben Mitchinson
    Adaptive Behaviour Research Group, Department of Psychology, The University of Sheffield, Sheffield S10 2TP, UK
    Proc Biol Sci 271:2509-16. 2004
    ..The agreement was good enough to suggest that the model captures many of the key features of the peripheral whisker system in the rat...
  35. ncbi request reprint Subcortical loops through the basal ganglia
    John G McHaffie
    Wake Forest University School of Medicine, Department of Neurobiology and Anatomy, Medical Center Boulevard, Winston Salem NC 27157 1010, USA
    Trends Neurosci 28:401-7. 2005
    ....
  36. ncbi request reprint Pharmacological evidence for an anticonvulsant relay in the rat ventromedial medulla
    Safa Shehab
    Department of Anatomy, Faculty of Medicine and Health Sciences, United Arab Emirates University, PO Box 17666, Al Ain, UAE
    Eur J Neurosci 26:2585-94. 2007
    ..Together these data establish the final functional link connecting brainstem anticonvulsant circuitry with reticulospinal systems controlling hindlimb musculature...
  37. ncbi request reprint Dopamine neurones form a discrete plexus with melanopsin cells in normal and degenerating retina
    Anthony A Vugler
    Division of Cellular Therapy, Institute of Ophthalmology, University College London, 11 43 Bath Street, London, EC1V 9EL, UK
    Exp Neurol 205:26-35. 2007
    ....
  38. ncbi request reprint Anatomical evidence for an anticonvulsant relay in the rat ventromedial medulla
    Safa Shehab
    Department of Anatomy, Faculty of Medicine and Health Sciences, United Arab Emirates University, PO Box 17666, Al Ain, UAE
    Eur J Neurosci 22:1431-44. 2005
    ....