Research Topics
| Margaret RaymanSummaryAffiliation: University of Surrey Country: UK Publications
Research Grants
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Detail Information
Publications
The argument for increasing selenium intakeMargaret P Rayman
Centre for Nutrition and Food Safety, School of Biomedical and Life Sciences, University of Surrey, Guildford GU2 7XH, UK
Proc Nutr Soc 61:203-15. 2002....
Food-chain selenium and human health: emphasis on intakeMargaret P Rayman
Nutritional Sciences Division, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey GU2 7XH, UK
Br J Nutr 100:254-68. 2008..The difficulties of balancing the risks and benefits in relation to Se intake are highlighted...
A randomized trial of selenium supplementation and risk of type-2 diabetes, as assessed by plasma adiponectinMargaret P Rayman
Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom
PLoS ONE 7:e45269. 2012..Plasma adiponectin concentration, a recognised independent predictor of type-2 diabetes risk and known to be correlated with circulating selenoprotein P, was the biomarker chosen...
Selenium and human healthMargaret P Rayman
Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK
Lancet 379:1256-68. 2012....
Plasma selenium and risk of dysglycemia in an elderly French population: results from the prospective Epidemiology of Vascular Ageing StudyTasnime N Akbaraly
INSERM, U888, F 34093, Montpellier, France Université Montpellier 1, Montpellier, France
Nutr Metab (Lond) 7:21. 2010..Given these controversial results, we investigated prospectively the relationship between baseline plasma selenium concentration and occurrence of dysglycemia (impaired fasting glucose or type 2 diabetes) in an elderly French cohort...
Effect of supplementation with high-selenium yeast on plasma lipids: a randomized trialMargaret P Rayman
University of Surrey, Guildford, United Kingdom
Ann Intern Med 154:656-65. 2011..High selenium status has been linked to elevated blood cholesterol levels in cross-sectional studies...
Maternal selenium status during early gestation and risk for preterm birthMargaret P Rayman
Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK
CMAJ 183:549-55. 2011....
Selenoproteins and human health: insights from epidemiological dataMargaret P Rayman
Division of Nutritional Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, GU2 7XH, UK
Biochim Biophys Acta 1790:1533-40. 2009..Future studies therefore need to determine not only selenium status, but genotype, both in selenoproteins and related pathways, when investigating the relationship of selenium with disease risk...
Dietary manipulation in musculoskeletal conditionsMargaret P Rayman
Nutritional Sciences Division, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK
Best Pract Res Clin Rheumatol 22:535-61. 2008..All arthritic patients, particularly those with inflammatory disease, should be advised to ensure a good dietary intake of antioxidants, copper and zinc. Supplementation with selenium and vitamin D may be advisable...
Food-chain selenium and human health: spotlight on speciationMargaret P Rayman
Nutritional Sciences Division, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey GU2 7XH, UK
Br J Nutr 100:238-53. 2008..There remain considerable gaps in our knowledge of the forms of Se that naturally occur in foods. Without adequate knowledge of Se speciation, false conclusions may be drawn when assessing Se requirements for optimal health...
Randomized controlled trial of the effect of selenium supplementation on thyroid function in the elderly in the United KingdomMargaret P Rayman
Nutritional Sciences Division, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom
Am J Clin Nutr 87:370-8. 2008....
Low selenium status is associated with the occurrence of the pregnancy disease preeclampsia in women from the United KingdomMargaret P Rayman
School of Biomedical and Molecular Sciences, University of Surrey, Guildford GU2 7XH, United Kingdom
Am J Obstet Gynecol 189:1343-9. 2003....
The use of high-selenium yeast to raise selenium status: how does it measure up?Margaret P Rayman
Centre for Nutrition and Food Safety, School of Biomedical and Molecular Sciences, University of Surrey, UK
Br J Nutr 92:557-73. 2004..It is concluded that Se-yeast from reputable manufacturers is adequately characterised, of reproducible quality, and that there is no evidence of toxicity even at levels far above the EC tolerable upper intake level of 300 microg/d...
Impact of selenium on mood and quality of life: a randomized, controlled trialMargaret Rayman
School of Biomedical and Molecular Sciences, University of Surrey, Guildford, GU2 7XH, UK
Biol Psychiatry 59:147-54. 2006..Selenium is known to be important to the brain. Three small, published studies have suggested an effect of selenium supplementation or deprivation on mood in healthy volunteers. We investigated these findings on a much larger scale...
Selenium in cancer prevention: a review of the evidence and mechanism of actionMargaret P Rayman
Division of Nutrition, Dietetics and Food, School of Biomedical and Molecular Sciences, University of Surrey, Guildford, UK
Proc Nutr Soc 64:527-42. 2005....
Effect of selenium status and supplementation with high-selenium yeast on plasma homocysteine and B vitamin concentrations in the UK elderlyBram Bekaert
Division of Nutritional Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK
Mol Nutr Food Res 52:1324-33. 2008..After 6 months of Se supplementation, only Se concentration had changed significantly. Supplementation with Se does not affect tHcy concentration in the UK elderly population...
Interaction between single nucleotide polymorphisms in selenoprotein P and mitochondrial superoxide dismutase determines prostate cancer riskMatthew L Cooper
Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom
Cancer Res 68:10171-7. 2008....
Abnormal iron parameters in the pregnancy syndrome preeclampsiaMargaret P Rayman
School of Biomedical and Life Sciences, University of Surrey, Guildford, United Kongdom
Am J Obstet Gynecol 187:412-8. 2002....
Randomised, double blind, placebo-controlled trial of selenium supplementation in adult asthmaSeif O Shaheen
Respiratory Epidemiology and Public Health Group, NHLI at Imperial College London, Emmanuel Kaye Building, Manresa Road, London SW3 6LR, UK
Thorax 62:483-90. 2007..The only previous trial of selenium supplementation in adults with asthma found no objective evidence of benefit but involved only 24 participants...
Research Grants
- Effect of Selenoprotein SNPs on Prostate Cancer RiskMargaret Rayman; Fiscal Year: 2005..Reduction of cancer incidence in these sub-groups would reduce the incidence of prostate cancer in the population. ..
