- The impact of chromatin modifiers on the timing of locus replication in mouse embryonic stem cellsHelle F Jørgensen
Lymphocyte Development Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, London W12 0NN, UK
Genome Biol 8:R169. 2007..This poised or bivalent state is also characterized by locus replication in early S-phase in ES cells, while replication timing is delayed in cells with restricted developmental options...
- Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3aB H Ramsahoye
Department of Hematology, Western General Hospital, EH4 2XU Edinburgh, United Kingdom
Proc Natl Acad Sci U S A 97:5237-42. 2000..Analysis of genomic methylation in transgenic Drosophila expressing Dnmt3a reveals that Dnmt3a is predominantly a CpG methylase but also is able to induce methylation at CpA and at CpT...