Pramila Ramani

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. doi request reprint High levels of polo-like kinase 1 and phosphorylated translationally controlled tumor protein indicate poor prognosis in neuroblastomas
    Pramila Ramani
    School of Cellular and Molecular Medicine, University of Bristol, School of Medical Sciences, University Walk, Bristol, BS8 1TD, UK
    J Neurooncol 125:103-11. 2015
  2. doi request reprint High proliferation index, as determined by immunohistochemical expression of Aurora kinase B and geminin, indicates poor prognosis in neuroblastomas
    Pramila Ramani
    School of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, University Walk, Bristol, BS8 1TD, UK
    Virchows Arch 467:319-27. 2015
  3. doi request reprint High phosphohistone H3 expression correlates with adverse clinical, biological, and pathological factors in neuroblastomas
    Pramila Ramani
    Department of Histopathology, Bristol Royal Infirmary, Bristol, United Kingdom PR, St, EM, ESA Department of Cellular and Molecular Medicine, School of Medical Sciences PR, University of Bristol, Bristol, United KingdomSchool of Social and Community Medicine MTM, University of Bristol, Bristol, United Kingdom
    J Histochem Cytochem 63:397-407. 2015
  4. doi request reprint GLUT1 protein expression correlates with unfavourable histologic category and high risk in patients with neuroblastic tumours
    Pramila Ramani
    Department of Histopathology, Bristol Royal Infirmary, Bristol, BS2 8HW, UK
    Virchows Arch 462:203-9. 2013
  5. doi request reprint VEGF-C, VEGF-D and VEGFR-3 expression in peripheral neuroblastic tumours
    Pramila Ramani
    School of Cellular and Molecular Medicine, University of Bristol, School of Medical Sciences, University Walk, Bristol, UK
    Histopathology 61:1006-16. 2012
  6. doi request reprint Podoplanin lymphatic density and invasion correlate with adverse clinicopathologic and biological factors and survival in neuroblastomas
    Pramila Ramani
    Department of Histopathology, Bristol Royal Infirmary, Bristol, UK
    Am J Surg Pathol 36:908-15. 2012
  7. doi request reprint PROX1 lymphatic density correlates with adverse clinicopathological factors, lymph node metastases and survival in neuroblastomas
    Pramila Ramani
    Department of Histopathology, Bristol Royal Infirmary, Bristol, BS2 8HW, UK
    J Neurooncol 108:375-83. 2012
  8. doi request reprint LYVE-1 upregulation and lymphatic invasion correlate with adverse prognostic factors and lymph node metastasis in neuroblastoma
    Pramila Ramani
    Department of Histopathology, Bristol Royal Infirmary, Bristol, BS2 8HW, UK
    Virchows Arch 460:183-91. 2012
  9. pmc Overexpression of carbonic anhydrase and HIF-1α in Wilms tumours
    Josiah V Dungwa
    Department of Histopathology, Bristol Royal Infirmary, Bristol BS2 8HW, UK
    BMC Cancer 11:390. 2011
  10. doi request reprint Angiogenin up-regulation correlates with adverse clinicopathological and biological factors, increased microvascular density and poor patient outcome in neuroblastomas
    Josiah V Dungwa
    Department of Histopathology, University Hospitals Bristol NHS Foundation Trust, Bristol, UK
    Histopathology 60:911-23. 2012

Detail Information

Publications14

  1. doi request reprint High levels of polo-like kinase 1 and phosphorylated translationally controlled tumor protein indicate poor prognosis in neuroblastomas
    Pramila Ramani
    School of Cellular and Molecular Medicine, University of Bristol, School of Medical Sciences, University Walk, Bristol, BS8 1TD, UK
    J Neurooncol 125:103-11. 2015
    ..After adjustment for MKI and MYCN amplification, and for risk-group, high pTCTP PI was also associated with significantly shorter OS. Our study shows that PLK1 provides valuable prognostic information in patients with neuroblastomas...
  2. doi request reprint High proliferation index, as determined by immunohistochemical expression of Aurora kinase B and geminin, indicates poor prognosis in neuroblastomas
    Pramila Ramani
    School of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, University Walk, Bristol, BS8 1TD, UK
    Virchows Arch 467:319-27. 2015
    ..Our study shows that in neuroblastomas, AURKB- or GMNN-based PI provides valuable prognostic information and high PI indicates aggressive disease...
  3. doi request reprint High phosphohistone H3 expression correlates with adverse clinical, biological, and pathological factors in neuroblastomas
    Pramila Ramani
    Department of Histopathology, Bristol Royal Infirmary, Bristol, United Kingdom PR, St, EM, ESA Department of Cellular and Molecular Medicine, School of Medical Sciences PR, University of Bristol, Bristol, United KingdomSchool of Social and Community Medicine MTM, University of Bristol, Bristol, United Kingdom
    J Histochem Cytochem 63:397-407. 2015
    ..In conclusion, high pHH3 expression correlates strongly with high MKI and MYCN amplification and indicates poor prognosis in neuroblastomas. ..
  4. doi request reprint GLUT1 protein expression correlates with unfavourable histologic category and high risk in patients with neuroblastic tumours
    Pramila Ramani
    Department of Histopathology, Bristol Royal Infirmary, Bristol, BS2 8HW, UK
    Virchows Arch 462:203-9. 2013
    ..Our data may have clinical significance because GLUT1 was also present in a higher proportion of high-risk NTs...
  5. doi request reprint VEGF-C, VEGF-D and VEGFR-3 expression in peripheral neuroblastic tumours
    Pramila Ramani
    School of Cellular and Molecular Medicine, University of Bristol, School of Medical Sciences, University Walk, Bristol, UK
    Histopathology 61:1006-16. 2012
    ....
  6. doi request reprint Podoplanin lymphatic density and invasion correlate with adverse clinicopathologic and biological factors and survival in neuroblastomas
    Pramila Ramani
    Department of Histopathology, Bristol Royal Infirmary, Bristol, UK
    Am J Surg Pathol 36:908-15. 2012
    ..These findings suggest that PDPN has the potential to provide valuable prognostic information to clinicians for risk assessment in NBs...
  7. doi request reprint PROX1 lymphatic density correlates with adverse clinicopathological factors, lymph node metastases and survival in neuroblastomas
    Pramila Ramani
    Department of Histopathology, Bristol Royal Infirmary, Bristol, BS2 8HW, UK
    J Neurooncol 108:375-83. 2012
    ..Increased LD, LI and cellular expression correlated with adverse factors in NBs. Increased LD correlated with LNM suggesting that PROX1 contributes to neuroblastoma progression and lymphatic spread...
  8. doi request reprint LYVE-1 upregulation and lymphatic invasion correlate with adverse prognostic factors and lymph node metastasis in neuroblastoma
    Pramila Ramani
    Department of Histopathology, Bristol Royal Infirmary, Bristol, BS2 8HW, UK
    Virchows Arch 460:183-91. 2012
    ..055). Significant upregulation of LYVE-1 and the presence of LI in patients with stage 4 and high-risk disease, MYCN-amplification and LNM suggests that LYVE-1 may have value as predictors of outcome...
  9. pmc Overexpression of carbonic anhydrase and HIF-1α in Wilms tumours
    Josiah V Dungwa
    Department of Histopathology, Bristol Royal Infirmary, Bristol BS2 8HW, UK
    BMC Cancer 11:390. 2011
    ..Overexpression of carbonic anhydrase (CA IX) is associated with poor survival in several adult-type cancers but its expression is undocumented in Wilms tumour (WT), the most common tumour of the paediatric kidney...
  10. doi request reprint Angiogenin up-regulation correlates with adverse clinicopathological and biological factors, increased microvascular density and poor patient outcome in neuroblastomas
    Josiah V Dungwa
    Department of Histopathology, University Hospitals Bristol NHS Foundation Trust, Bristol, UK
    Histopathology 60:911-23. 2012
    ....
  11. doi request reprint Carbonic anhydrase IX up-regulation is associated with adverse clinicopathologic and biologic factors in neuroblastomas
    Josiah V Dungwa
    Department of Histopathology, Bristol Royal Infirmary, BS2 8HW Bristol, UK
    Hum Pathol 43:1651-60. 2012
    ..Carbonic anhydrase IX is expressed at significantly higher levels in neuroblastomas from patients with adverse clinicopathologic and biologic factors indicating that it is a biomarker of aggressive disease in neuroblastomas...
  12. pmc Angiogenin expression in human kidneys and Wilms' tumours: relationship with hypoxia and angiogenic factors
    Pramila Ramani
    Department of Histopathology, Bristol Royal Infirmary, University Hospitals Bristol NHS Foundation Trust, Bristol, UK Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, University Walk, Bristol, UK
    Int J Exp Pathol 94:115-25. 2013
    ..Our study contributes to the understanding of angiogenesis during development and in WTs...
  13. doi request reprint HIF-1α up-regulation is associated with adverse clinicopathological and biological factors in neuroblastomas
    Josiah V Dungwa
    Department of Histopathology, Bristol Royal Infirmary, Bristol, UK
    Histopathology 61:417-27. 2012
    ..To study the expression of hypoxia-inducible factor 1α (HIF-1α) in clinical neuroblastoma (NB) samples and its association with the clinicopathological features, biological features and survival of NB patients...
  14. doi request reprint Aurora kinase A is superior to Ki67 as a prognostic indicator of survival in neuroblastoma
    Pramila Ramani
    School of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, Bristol, UK Department of Histopathology, University Hospitals Bristol NHS Foundation Trust, Bristol, UK
    Histopathology 66:370-9. 2015
    ..To compare the expression and prognostic value of the cell cycle markers Aurora kinase A (AURKA) and Ki67 in neuroblastoma, because AURKA expression levels have greater prognostic significance than those of Ki67 in some cancers...