Alan D Radford
Affiliation: University of Liverpool
- Molecular characterization of the uncultivatable hemotropic bacterium Mycoplasma haemofelisEmily N Barker
School of Veterinary Sciences, University of Bristol, Langford, BS40 5DU, UK
Vet Res 42:83. 2011..A number of immunogenic proteins, and a potential mechanism for host immune system evasion, have been identified...
- The challenge for the next generation of feline calicivirus vaccinesAlan D Radford
Department of Veterinary Clinical Science, University of Liverpool, Leahurst, Chester High Road, Neston, S Wirral CH64 7TE, UK
Vet Microbiol 117:14-8. 2006....
- Comparison of the ability of feline calicivirus (FCV) vaccines to neutralise a panel of current UK FCV isolatesCarol J Porter
Small Animal Infectious Diseases Group, Department of Veterinary Pathology, University of Liverpool Veterinary Teaching Hospital, Leahurst, Chester High Road, Neston CH64 7TE, United Kingdom
J Feline Med Surg 10:32-40. 2008..In addition as cats became older their risk of shedding FCV decreased...
- Large-scale spatial and temporal genetic diversity of feline calicivirusKaren P Coyne
University of Liverpool, Institute of Infection and Global Health, School of Veterinary Science, Leahurst Campus, Neston, South Wirral
J Virol 86:11356-67. 2012..This complexity provides a benchmark, for the first time, against which vaccine cross-protection at both local and national levels can be judged...
- Long-term analysis of feline calicivirus prevalence and viral shedding patterns in naturally infected colonies of domestic catsKaren P Coyne
Department of Veterinary Clinical Sciences, University of Liverpool Veterinary Teaching Hospital, Leahurst, Chester High Road, Neston CH64 7TE, United Kingdom
Vet Microbiol 118:12-25. 2006....
- High genetic diversity of the immunodominant region of the feline calicivirus capsid gene in endemically infected cat coloniesAlan D Radford
Department of Veterinary Clinical Sciences, University of Liverpool, Leahurst Veterinary Teaching Hospital, Chester High Road, Neston, S Wirral, CH64 7TE, UK
Virus Genes 27:145-55. 2003..We suggest that endemically infected colonies of cats may be important generators of genetic diversity for FCV and that this may ultimately lead to the generation of new strains...
- Longitudinal molecular epidemiological analysis of feline calicivirus infection in an animal shelter: a model for investigating calicivirus transmission within high-density, high-turnover populationsKaren P Coyne
Department of Veterinary Pathology, University of Liverpool, Leahurst, Chester High Road, South Wirral CH64 7TE, United Kingdom
J Clin Microbiol 45:3239-44. 2007..These data suggest that despite the high prevalence and presence of multiple strains of FCV within the shelter, the spread of such pathogens may be restricted by various control measures, including good hygiene and biosecurity...
- Evolutionary mechanisms of persistence and diversification of a calicivirus within endemically infected natural host populationsKaren P Coyne
Department of Veterinary Clinical Sciences, University of Liverpool, Leahurst, Chester High Road, South Wirral CH64 7TE, United Kingdom
J Virol 81:1961-71. 2007..Reiteration of both progressive evolution and variant reinfection appeared to lead to a gradual increase in the diversity of a given strain of virus, both in the individual and in the population, until eventually new strains emerged...
- Feline calicivirusAlan D Radford
University of Liverpool Veterinary Teaching Hospital, Leahurst, Chester High Road, Neston, S Wirral, CH64 7TE, United Kingdom
Vet Res 38:319-35. 2007..Challenges for the future will necessarily focus on how to control the variability of this virus particularly in relation to emerging virulent strains and vaccination...
- Prevalence of feline chronic gingivo-stomatitis in first opinion veterinary practiceKatharine A E Healey
Department of Clinical Veterinary Sciences, University of Liverpool, Leahurst Veterinary Field Station, Chester High Road, Neston, S Wirral CH64 7TE, United Kingdom
J Feline Med Surg 9:373-81. 2007..No statistically significant difference (P>0.353) was found when the age, sex and breed of cats with FCGS were compared to data from cats without the condition...
- Duration of immunity (DOI)--The regulatory issuesRosalind M Gaskell
Small Animal Infectious Diseases Group, Faculty of Veterinary Science, University of Liverpool, Leahurst, Neston, Wirral CH64 7TE, UK
Vet Microbiol 117:80-5. 2006..The drawbacks of the present EU system are summarised, and the ways in which the situation is currently being approached and improved are presented...
- Human norovirus infection and the lessons from animal calicivirusesAlan D Radford
University of Liverpool, Leahurst Veterinary Teaching Hospital, Neston, S Wirral CH64 7TE, UK
Curr Opin Infect Dis 17:471-8. 2004..This review will describe recent advances in our understanding of human noroviruses. In addition, we will consider related nonhuman caliciviruses to highlight some potential difficulties in the control of caliciviral disease...
- RAS, FLT3, and C-KIT mutations in immunophenotyped canine leukemiasSuzanne G Usher
Small Animal Teaching Hospital, University of Liverpool, The Leahurst Campus, Neston, Wirral, UK
Exp Hematol 37:65-77. 2009..To determine the frequency of FLT3, C-KIT, and RAS mutations in canine leukemia patients...
- Application of next-generation sequencing technologies in virologyAlan D Radford
University of Liverpool, Institute of Infection and Global Health, Leahurst Campus, Chester High Road, Neston, South Wirral CH64 7TE, UK
J Gen Virol 93:1853-68. 2012..An exciting era of viral exploration has begun, and will set us new challenges to understand the role of newly discovered viral diversity in both disease and health...
- Detection of squirrel poxvirus by nested and real-time PCR from red (Sciurus vulgaris) and grey (Sciurus carolinensis) squirrelsJanus W Atkin
Department of Veterinary Pathology, University of Liverpool, Neston, Cheshire, UK
BMC Vet Res 6:33. 2010..Although a nested PCR assay has been used successfully to study the epidemiology of SQPV, samples have a long processing time and the assay is not quantifiable...
- Molecular phylogenetic and evolutionary analyses of Muar strain of Japanese encephalitis virus reveal it is the missing fifth genotypeManal A F Mohammed
Brain Infections Group, Institute of Infection and Global Health, University of Liverpool, Liverpool, UK
Infect Genet Evol 11:855-62. 2011..No strong evidence for positive selection was found between JEV strains of the five genotypes and the E gene has generally been subjected to strong purifying selection...
- Sequence analysis of MHC DRB alleles in domestic cats from the United KingdomLorna J Kennedy
Mammalian Immunogenetics Research Group, Faculty of Veterinary Science, University of Liverpool, Crown Street, Liverpool, L69 7ZJ, UK
Immunogenetics 54:348-52. 2002..Analysis of these 24 alleles reveals a similar pattern of MHC polymorphism to that seen in other mammals, with three regions of hypervariability...
- Feline leucocyte antigen class II polymorphism and susceptibility to feline infectious peritonitisDiane D Addie
Institute of Comparative Medicine, Companion Animal Diagnostics, Bearsden Road, Bearsden, Glasgow, Scotland G61 1QH, UK
J Feline Med Surg 6:59-62. 2004..However, the analysis was complicated by apparent breed variation in FLA-DRB and the small number of individuals in this study...