Naila Rabbani

Summary

Affiliation: University of Warwick
Country: UK

Publications

  1. doi request reprint Glycation research in amino acids: a place to call home
    Naila Rabbani
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Clifford Bridge Road, Coventry, CV2 2DX, UK
    Amino Acids 42:1087-96. 2012
  2. pmc Glycation of LDL by methylglyoxal increases arterial atherogenicity: a possible contributor to increased risk of cardiovascular disease in diabetes
    Naila Rabbani
    Warwick Medical School, Clinical Sciences Research Institute, University of Warwick, University Hospital, Coventry, UK
    Diabetes 60:1973-80. 2011
  3. doi request reprint The dicarbonyl proteome: proteins susceptible to dicarbonyl glycation at functional sites in health, aging, and disease
    Naila Rabbani
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, Coventry CV2 2DX, UK
    Ann N Y Acad Sci 1126:124-7. 2008
  4. doi request reprint Emerging role of thiamine therapy for prevention and treatment of early-stage diabetic nephropathy
    N Rabbani
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Coventry, UK
    Diabetes Obes Metab 13:577-83. 2011
  5. doi request reprint Glyoxalase in diabetes, obesity and related disorders
    Naila Rabbani
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Coventry, UK
    Semin Cell Dev Biol 22:309-17. 2011
  6. pmc Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin
    Naila Rabbani
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Coventry, UK
    Diabetes 59:1038-45. 2010
  7. doi request reprint Effect of Irbesartan treatment on plasma and urinary markers of protein damage in patients with type 2 diabetes and microalbuminuria
    Naila Rabbani
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Coventry, CV2 2DX, UK
    Amino Acids 42:1627-39. 2012
  8. pmc Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes
    James R Larkin
    Warwick Medical School, Clinical Sciences Research Laboratories, University of Warwick, University Hospital, Coventry, United Kingdom
    PLoS ONE 7:e53175. 2012
  9. doi request reprint Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome
    Naila Rabbani
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Clifford Bridge Road, Coventry, CV2 2DX, UK
    Amino Acids 42:1133-42. 2012
  10. doi request reprint Glyoxalase in ageing
    Mingzhan Xue
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Coventry, UK
    Semin Cell Dev Biol 22:293-301. 2011

Collaborators

Detail Information

Publications25

  1. doi request reprint Glycation research in amino acids: a place to call home
    Naila Rabbani
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Clifford Bridge Road, Coventry, CV2 2DX, UK
    Amino Acids 42:1087-96. 2012
    ..In this section of amino acids, research on glycation is a qualifier for publication. Glycation research now has a place to call home...
  2. pmc Glycation of LDL by methylglyoxal increases arterial atherogenicity: a possible contributor to increased risk of cardiovascular disease in diabetes
    Naila Rabbani
    Warwick Medical School, Clinical Sciences Research Institute, University of Warwick, University Hospital, Coventry, UK
    Diabetes 60:1973-80. 2011
    ..To study whether modification of LDL by methylglyoxal (MG), a potent arginine-directed glycating agent that is increased in diabetes, is associated with increased atherogenicity...
  3. doi request reprint The dicarbonyl proteome: proteins susceptible to dicarbonyl glycation at functional sites in health, aging, and disease
    Naila Rabbani
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, Coventry CV2 2DX, UK
    Ann N Y Acad Sci 1126:124-7. 2008
    ....
  4. doi request reprint Emerging role of thiamine therapy for prevention and treatment of early-stage diabetic nephropathy
    N Rabbani
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Coventry, UK
    Diabetes Obes Metab 13:577-83. 2011
    ..The probable explanations for this are discussed. Further definitive trials for prevention of progression of early-stage diabetic nephropathy by thiamine are now required...
  5. doi request reprint Glyoxalase in diabetes, obesity and related disorders
    Naila Rabbani
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Coventry, UK
    Semin Cell Dev Biol 22:309-17. 2011
    ....
  6. pmc Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin
    Naila Rabbani
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Coventry, UK
    Diabetes 59:1038-45. 2010
    ..The aim of this study was to investigate whether apolipoprotein B100 of LDL suffers increased damage by glycation, oxidation, and nitration in patients with type 2 diabetes, including patients receiving metformin therapy...
  7. doi request reprint Effect of Irbesartan treatment on plasma and urinary markers of protein damage in patients with type 2 diabetes and microalbuminuria
    Naila Rabbani
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Coventry, CV2 2DX, UK
    Amino Acids 42:1627-39. 2012
    ..This is likely achieved by blocking angiotensin II signalling and related down-regulation of glyoxalase 1 and may contribute to health benefits of Irbesartan therapy...
  8. pmc Glucose-induced down regulation of thiamine transporters in the kidney proximal tubular epithelium produces thiamine insufficiency in diabetes
    James R Larkin
    Warwick Medical School, Clinical Sciences Research Laboratories, University of Warwick, University Hospital, Coventry, United Kingdom
    PLoS ONE 7:e53175. 2012
    ..This is a novel mechanism of thiamine insufficiency linked to diabetic nephropathy...
  9. doi request reprint Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome
    Naila Rabbani
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Clifford Bridge Road, Coventry, CV2 2DX, UK
    Amino Acids 42:1133-42. 2012
    ..Improved understanding of the DCP will likely have profound importance for human health, longevity and treatment of disease...
  10. doi request reprint Glyoxalase in ageing
    Mingzhan Xue
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Coventry, UK
    Semin Cell Dev Biol 22:293-301. 2011
    ..The glyoxalase system and Glo1 expression particularly is therefore likely linked to healthy ageing...
  11. doi request reprint Disturbance of B-vitamin status in people with type 2 diabetes in Indonesia--link to renal status, glycemic control and vascular inflammation
    Antonysunil Adaikalakoteswari
    Clinical Sciences Research Laboratories, Warwick Medical School, University of Warwick, University Hospital, Coventry CV2 2DX, UK
    Diabetes Res Clin Pract 95:415-24. 2012
    ..The aim of this study is to assess the disturbance of thiamine and other B-vitamin status of patients with type 2 diabetes in Indonesia...
  12. ncbi request reprint Quantitation of markers of protein damage by glycation, oxidation, and nitration in peritoneal dialysis
    Naila Rabbani
    Warwick Medical School, Clinical Sciences Research Institute, University of Warwick, University Hospital, Coventry, UK
    Perit Dial Int 29:S51-6. 2009
    ....
  13. pmc Dicarbonyls linked to damage in the powerhouse: glycation of mitochondrial proteins and oxidative stress
    Naila Rabbani
    Protein Damage and Systems Biology Research Group, Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Coventry CV2 2DX, UK
    Biochem Soc Trans 36:1045-50. 2008
    ..Future research will address the functional charges in mitochondrial proteins that are the targets for dicarbonyl glycation...
  14. doi request reprint Protein damage in diabetes and uremia--identifying hotspots of proteome damage where minimal modification is amplified to marked pathophysiological effect
    Paul J Thornalley
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Coventry CV2 2DX, UK
    Free Radic Res 45:89-100. 2011
    ..The role of mathematical systems biology, bioinformatics and proteome dynamics in future investigations is discussed...
  15. pmc Imidazopurinones are markers of physiological genomic damage linked to DNA instability and glyoxalase 1-associated tumour multidrug resistance
    Paul J Thornalley
    Warwick Medical School, Clinical Sciences Research Institute, University of Warwick, University Hospital, Coventry CV2 2DX, UK
    Nucleic Acids Res 38:5432-42. 2010
    ....
  16. doi request reprint Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation
    Mingzhan Xue
    Clinical Sciences Research Laboratories, Warwick Medical School, University of Warwick, University Hospital, Coventry CV2 2DX, UK
    Biochem J 443:213-22. 2012
    ..We conclude that dicarbonyl stress is countered by up-regulation of Glo1 in the Nrf2 stress-responsive system, protecting protein and DNA from increased damage and preserving cell function...
  17. doi request reprint Highlights and hotspots of protein glycation in end-stage renal disease
    Paul J Thornalley
    Protein Damage and Systems Biology Research Group, Clinical Sciences Research Institute, Warwick Medical School, University Hospital, University of Warwick, Coventry, United Kingdom
    Semin Dial 22:400-4. 2009
    ....
  18. doi request reprint Dietary and synthetic activators of the antistress gene response in treatment of renal disease
    Paul J Thornalley
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Coventry, United Kingdom
    J Ren Nutr 22:195-202. 2012
    ....
  19. pmc Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease
    Mingzhan Xue
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Coventry, UK
    Diabetes 57:2809-17. 2008
    ..The aim of this study was to assess whether activation of nrf2 by sulforaphane in human microvascular endothelial cells prevents metabolic dysfunction in hyperglycemia...
  20. doi request reprint Glyoxalase in tumourigenesis and multidrug resistance
    Paul J Thornalley
    Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Coventry, UK
    Semin Cell Dev Biol 22:318-25. 2011
    ..Further research is required urgently for next stage clinical translation. Finally, overexpression of glyoxalase 1 may be linked to multidrug resistance in chemotherapy of other disease - such as microbial infections...
  21. doi request reprint Determination of types and binding sites of advanced glycation end products for substance P
    Andrea F Lopez-Clavijo
    Warwick Centre for Analytical Science, Department of Chemistry, University of Warwick, Coventry, CV4 7AL, United Kingdom
    Anal Chem 84:10568-75. 2012
    ....
  22. doi request reprint Assay of 3-nitrotyrosine in tissues and body fluids by liquid chromatography with tandem mass spectrometric detection
    Naila Rabbani
    Protein Damage and Systems Biology Research Group, Clinical Sciences Research Institute, Warwick Medical School, University of Warwick, University Hospital, Coventry, United Kingdom
    Methods Enzymol 440:337-59. 2008
    ..Changes of 3-nitrotyrosine residue and free 3-nitrotyrosine in diabetes, cirrhosis, acute and chronic renal failure, and neurological disorders, including Alzheimer's disease, are presented and compared with independent estimates...
  23. pmc Reversal of hyperglycemia-induced angiogenesis deficit of human endothelial cells by overexpression of glyoxalase 1 in vitro
    Usman Ahmed
    Department of Biological Sciences, University of Essex, Colchester, United Kingdom
    Ann N Y Acad Sci 1126:262-4. 2008
    ..We conclude that increased protection against dicarbonyl glycation of endothelial cell protein protects hyperglycemia-induced angiogenesis deficit...
  24. pmc Preparation of nucleotide advanced glycation endproducts--imidazopurinone adducts formed by glycation of deoxyguanosine with glyoxal and methylglyoxal
    Thomas Fleming
    Department of Biological Sciences, University of Essex, Colchester, United Kingdom
    Ann N Y Acad Sci 1126:280-2. 2008
    ..Analysis of dG-G, dG-MG, and the oxidative marker 8-hydroxydeoxyguanosine in the DNA of cultured human cells and mononuclear leukocytes showed that nucleotide advanced glycation endproducts are major markers of DNA damage in human cells...
  25. ncbi request reprint High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A
    Dachun Yao
    Juvenile Diabetes Research Foundation International Center for Diabetic Complications Research, Albert Einstein College of Medicine, Bronx, New York 10461, USA
    J Biol Chem 282:31038-45. 2007
    ..This novel mechanism for regulating gene expression may play a role in the pathobiology of diabetic vascular disease...