N Purandare

Summary

Affiliation: University of Manchester
Country: UK

Publications

  1. pmc Prevention of dementia: Role of vascular risk factors and cerebral emboli
    Nitin Purandare
    Psychiatry Research Group, The University of Manchester, University Place, Manchester, UK
    Indian J Psychiatry 51:S39-43. 2009
  2. doi Association of cerebral emboli with accelerated cognitive deterioration in Alzheimer's disease and vascular dementia
    Nitin Purandare
    Manchester Academic Health Science Center, University of Manchester, UK
    Am J Psychiatry 169:300-8. 2012
  3. pmc What are the benefits of cognitive enhancers for Alzheimer's Disease: use of Population Impact Measures
    Udaya P Gammanpila
    Specialist Registrar in Psychiatry, Forest House, Royal Oldham Hospital, Rochdale Road, Oldham, OL1 2JH, UK
    BMC Geriatr 7:25. 2007
  4. ncbi Knowledge of dementia among South Asian (Indian) older people in Manchester, UK
    Nitin Purandare
    School of Psychiatry and Behavioural Sciences, University of Manchester, Manchester, UK
    Int J Geriatr Psychiatry 22:777-81. 2007
  5. ncbi Asymptomatic spontaneous cerebral emboli predict cognitive and functional decline in dementia
    Nitin Purandare
    Division of Psychiatry, University of Manchester, Manchester, UK
    Biol Psychiatry 62:339-44. 2007
  6. doi Suicide in dementia: 9-year national clinical survey in England and Wales
    Nitin Purandare
    Psychiatry Research Group, School of Community Based Medicine, University of Manchester, University Place, Oxford Road, Manchester M13 9PL, UK
    Br J Psychiatry 194:175-80. 2009
  7. doi Cerebral emboli in the genesis of dementia
    Nitin Purandare
    Senior Lecturer in Old Age Psychiatry, Psychiatry Research Group, The University of Manchester, Manchester, UK
    J Neurol Sci 283:17-20. 2009
  8. doi Preventing dementia: role of vascular risk factors and cerebral emboli
    Nitin Purandare
    Psychiatry Research Group, Room 3 319, 3rd Floor East, University Place, University of Manchester, Oxford Road, Manchester M13 9PL, UK
    Br Med Bull 91:49-59. 2009
  9. doi Dental health of community-living older people attending secondary healthcare: a cross-sectional comparison between those with and without diagnosed mental illness
    Nitin Purandare
    Psychiatry Research Group, School of Community Based Medicine, University of Manchester and Manchester Mental Health and Social Care Trust, Old Age Psychiatry, Manchester, UK
    Int Psychogeriatr 22:417-25. 2010
  10. ncbi Deletion/insertion polymorphism of the angiotensin-converting enzyme gene and white matter hyperintensities in dementia: A pilot study
    Nitin Purandare
    Division of Psychiatry, Education and Research Center, South Manchester University Hospital, Manchester, United Kingdom
    J Am Geriatr Soc 54:1395-400. 2006

Collaborators

Detail Information

Publications32

  1. pmc Prevention of dementia: Role of vascular risk factors and cerebral emboli
    Nitin Purandare
    Psychiatry Research Group, The University of Manchester, University Place, Manchester, UK
    Indian J Psychiatry 51:S39-43. 2009
    ..For example, asymptomatic spontaneous cerebral emboli have been shown to be more frequent and associated with a more rapid progression of dementia in both AD and vascular dementia...
  2. doi Association of cerebral emboli with accelerated cognitive deterioration in Alzheimer's disease and vascular dementia
    Nitin Purandare
    Manchester Academic Health Science Center, University of Manchester, UK
    Am J Psychiatry 169:300-8. 2012
    ..The authors investigated the effect of cerebral emboli on cognitive and functional decline in both Alzheimer's disease and vascular dementia patients over a 2-year period...
  3. pmc What are the benefits of cognitive enhancers for Alzheimer's Disease: use of Population Impact Measures
    Udaya P Gammanpila
    Specialist Registrar in Psychiatry, Forest House, Royal Oldham Hospital, Rochdale Road, Oldham, OL1 2JH, UK
    BMC Geriatr 7:25. 2007
    ..The study aims to quantify the population impact of prescribing cholinesterase inhibitors to slow the cognitive decline in Alzheimer's disease (AD), and to compare with the benefit of treating hypertension to prevent the onset of AD...
  4. ncbi Knowledge of dementia among South Asian (Indian) older people in Manchester, UK
    Nitin Purandare
    School of Psychiatry and Behavioural Sciences, University of Manchester, Manchester, UK
    Int J Geriatr Psychiatry 22:777-81. 2007
    ..The aim of this study was to examine knowledge of dementia in South Asian older people, as compared with Caucasian older people...
  5. ncbi Asymptomatic spontaneous cerebral emboli predict cognitive and functional decline in dementia
    Nitin Purandare
    Division of Psychiatry, University of Manchester, Manchester, UK
    Biol Psychiatry 62:339-44. 2007
    ..Spontaneous cerebral emboli (SCE) are frequent in Alzheimer's disease (AD) and vascular dementia (VaD). We investigated the effect of SCE on the rates of cognitive and functional decline in AD and VaD...
  6. doi Suicide in dementia: 9-year national clinical survey in England and Wales
    Nitin Purandare
    Psychiatry Research Group, School of Community Based Medicine, University of Manchester, University Place, Oxford Road, Manchester M13 9PL, UK
    Br J Psychiatry 194:175-80. 2009
    ..Knowledge of suicide in people with dementia is limited to small case series...
  7. doi Cerebral emboli in the genesis of dementia
    Nitin Purandare
    Senior Lecturer in Old Age Psychiatry, Psychiatry Research Group, The University of Manchester, Manchester, UK
    J Neurol Sci 283:17-20. 2009
    ..SCE may represent a potentially treatable target to slow and possibly prevent dementia, both AD and VaD...
  8. doi Preventing dementia: role of vascular risk factors and cerebral emboli
    Nitin Purandare
    Psychiatry Research Group, Room 3 319, 3rd Floor East, University Place, University of Manchester, Oxford Road, Manchester M13 9PL, UK
    Br Med Bull 91:49-59. 2009
    ..Dementia, Alzheimer's disease and vascular dementia being two main causes, is major and growing health problem. Vascular risk factors are thought to be involved in the causation of both dementias...
  9. doi Dental health of community-living older people attending secondary healthcare: a cross-sectional comparison between those with and without diagnosed mental illness
    Nitin Purandare
    Psychiatry Research Group, School of Community Based Medicine, University of Manchester and Manchester Mental Health and Social Care Trust, Old Age Psychiatry, Manchester, UK
    Int Psychogeriatr 22:417-25. 2010
    ..Mental illness and cognitive impairment are risk factors for poor dental health...
  10. ncbi Deletion/insertion polymorphism of the angiotensin-converting enzyme gene and white matter hyperintensities in dementia: A pilot study
    Nitin Purandare
    Division of Psychiatry, Education and Research Center, South Manchester University Hospital, Manchester, United Kingdom
    J Am Geriatr Soc 54:1395-400. 2006
    ..To examine the association between the angiotensin-converting enzyme (ACE) deletion/insertion (D/I) polymorphism and white matter hyperintensities (WMHs) in patients with dementia...
  11. ncbi Cerebral emboli and depressive symptoms in dementia
    Nitin Purandare
    University of Manchester, Division of Psychiatry, Education and Research Centre, South Manchester University Hospital, Manchester M23 9LT, UK
    Br J Psychiatry 189:260-3. 2006
    ..The vascular depression hypothesis and our recent findings of increased frequency of spontaneous cerebral emboli in dementia suggest that such emboli may be involved in the causation of depressive symptoms in dementia...
  12. ncbi Paradoxical embolization: a potential cause of cerebral damage in Alzheimer's disease?
    N Purandare
    Division of Psychiatry, Education and Research Center, Wythenshawe Hospital, Wythenshawe, Manchester, M23 9LT, UK
    Neurol Res 28:679-84. 2006
    ..We reviewed the potential role of paradoxical embolization in AD...
  13. ncbi Cholinesterase inhibitors for Alzheimer's disease: variations in clinical practice in the north-west of England
    Nitin Purandare
    Department of Psychiatary, University of Manchester, Manchester, UK
    Int J Geriatr Psychiatry 21:961-4. 2006
    ..The implementation of the original NICE (2001) guidance that made these drugs available in the UK was not examined in this review process, and was the objective of this study...
  14. ncbi Biomarkers of cerebrovascular disease in dementia
    S Mills
    Division of Imaging Science, University of Manchester, Wolfson Molecular Imaging Centre, 27 Palatine Rd, Withington, Manchester, UK
    Br J Radiol 80:S128-45. 2007
    ....
  15. doi Activities enjoyed by patients with dementia together with their spouses and psychological morbidity in carers
    R Searson
    Old Age Psychiatry, North Manchester General Hospital, Manchester Mental Health and Social Care Trust, Manchester, UK
    Aging Ment Health 12:276-82. 2008
    ..Facilitating activities that are enjoyed by both patients with dementia and spouses may be an alternative intervention strategy to reduce carer burden...
  16. ncbi Paradoxical embolisation and cerebral white matter lesions in dementia
    N Purandare
    University of Manchester, Division of Psychiatry, Education and Research Centre, Wythenshawe Hospital, Wythenshawe, Manchester M23 9LT, UK
    Br J Radiol 81:30-4. 2008
    ..In addition, there is a significant negative correlation between SCE and DWMH in VaD, which supports the hypothesis that VaD may be the result of ischaemic injury, predominantly reflecting embolic aetiology...
  17. ncbi Depressive symptoms in patients with Alzheimer's disease
    N Purandare
    University Department of Psychiatry, Withington Hospital, Manchester, UK
    Int J Geriatr Psychiatry 16:960-4. 2001
    ..CONCLUSION: Depressive symptoms occur in AD when co-existing depression is ruled out. Their recognition has implications for the diagnosis of major depression in these patients...
  18. ncbi Asymptomatic spontaneous cerebral emboli and cognitive decline in a cohort of older people: a prospective study
    Richard C Oude Voshaar
    University of Manchester, Division of Psychiatry, Education and Research Centre, South Manchester University Hospital, Wythenshawe, Manchester, UK
    Int J Geriatr Psychiatry 22:794-800. 2007
    ..Asymptomatic spontaneous cerebral emboli (SCE) are common in dementia and are associated with cognitive decline in dementia. The significance of their presence in older people is unknown...
  19. ncbi Coping strategies and social support in old age psychosis
    Katherine Berry
    School of Psychological Sciences, University of Manchester, Rutherford Building, Manchester Science Park, Lloyd Street North, Manchester, UK
    Soc Psychiatry Psychiatr Epidemiol 41:280-4. 2006
    ..This study therefore aimed to explore coping in older patients with psychosis...
  20. doi The effect of musculoskeletal pain on sexual function in middle-aged and elderly european men: results from the european male ageing study
    Abdelouahid Tajar
    Arthritis Research UK Epidemiology Unit, Oxford Road, The University of Manchester, Manchester M13 9PT, United Kingdom
    J Rheumatol 38:370-7. 2011
    ..To determine whether musculoskeletal pain was associated with impaired sexual function in a population sample of middle-aged and older men...
  21. ncbi Cerebral emboli and paradoxical embolisation in dementia: a pilot study
    Nitin Purandare
    University of Manchester, School of Psychiatry and Behavioural Sciences, Education and Research Centre, Wythenshawe Hospital, Wythenshawe, Manchester M23 9LT, UK
    Int J Geriatr Psychiatry 20:12-6. 2005
    ....
  22. ncbi Clinical practice with anti-dementia drugs: a consensus statement from British Association for Psychopharmacology
    Alistair Burns
    University of Manchester, Manchester, UK
    J Psychopharmacol 20:732-55. 2006
    ..Patients, their carers, and clinicians deserve to be optimistic in a field which often attracts therapeutic nihilism...
  23. pmc Cerebral emboli as a potential cause of Alzheimer's disease and vascular dementia: case-control study
    Nitin Purandare
    Department of Psychiatry, University of Manchester, Manchester
    BMJ 332:1119-24. 2006
    ..To compare the occurrence of spontaneous cerebral emboli and venous to arterial circulation shunts in patients with Alzheimer's disease or vascular dementia and controls without dementia...
  24. pmc Genetic associations between cathepsin D exon 2 C-->T polymorphism and Alzheimer's disease, and pathological correlations with genotype
    Y Davidson
    Clinical Neuroscience Research Group, University of Manchester, Greater Manchester Neurosciences Centre, Hope Hospital, Stott Lane, Salford M6 8HD, Manchester, UK
    J Neurol Neurosurg Psychiatry 77:515-7. 2006
    ....
  25. ncbi Asymptomatic spontaneous cerebral emboli and mood in a cohort of older people: a prospective study
    Richard C Oude Voshaar
    Division of Psychiatry, Education and Research Centre, University of Manchester, South Manchester University Hospital, Wythenshawe, Manchester, United Kingdom
    Am J Geriatr Psychiatry 15:1057-60. 2007
    ..To examine whether asymptomatic spontaneous cerebral emboli (SCE) predicts subsequent depression in older people...
  26. ncbi Activational effects of sex hormones on cognition in men
    A Ulubaev
    Department of Endocrinology, Manchester Royal Infirmary, The University of Manchester, Manchester, UK
    Clin Endocrinol (Oxf) 71:607-23. 2009
    ..Although there is a plethora of published research on the topic, results have been inconsistent with different studies reporting positive, negative or no effects of sex hormones on various aspects of mental agility...
  27. ncbi The effect of anticholinesterases on personality changes in Alzheimer's disease
    N Purandare
    Wythenshawe Hospital, Nell Lane, West Didsbury, Manchester, UK
    Aging Ment Health 6:350-4. 2002
    ..Further double blind prospective studies are needed to understand natural progression of personality changes in AD and to validate the findings of this study...
  28. ncbi Apolipoprotein E epsilon4 allele frequency and age at onset of Alzheimer's disease
    Yvonne Davidson
    Clinical Neuroscience Research Group, Division of Medicine and Neuroscience, University of Manchester, Greater Manchester Neurosciences Centre, Hope Hospital, Salford, UK
    Dement Geriatr Cogn Disord 23:60-6. 2007
    ..44, was highest in the 60-69 years age class, progressively decreasing either side of this age group. APOE epsilon4 allele therefore has its maximum impact between onset ages of between 60 and 70 years...
  29. ncbi Perceived mental health needs and adequacy of service provision to older people in care homes in the UK: a national survey
    Nitin Purandare
    University of Manchester, School of Psychiatry and Behavioural Sciences, 2nd Floor, Education and Research Centre, Wythenshawe Hospital, Wythenshawe, Manchester, UK
    Int J Geriatr Psychiatry 19:549-53. 2004
    ..To assess perceived need and adequacy of service provision by old age psychiatrists (OAPs) to older people living in care homes in the UK...
  30. ncbi Orofacial dyskinesia, frontal lobe dysfunction, and coping in older people with psychosis
    Katherine Berry
    Division of Psychiatry, Faculty of Medical and Human Sciences, School of Medicine, Manchester University, United Kingdom
    Am J Geriatr Psychiatry 15:800-6. 2007
    ..To investigate whether orofacial tardive dyskinesia (OTD) is associated with frontal lobe dysfunction and whether either are related to the coping abilities independent of psychiatric symptoms in older people with psychotic disorders...
  31. doi Endogenous hormones, androgen receptor CAG repeat length and fluid cognition in middle-aged and older men: results from the European Male Ageing Study
    David M Lee
    ARC Epidemiology Unit, Department of Medicine, Manchester Academic and Health Sciences Centre, Manchester Royal Infirmary, The University of Manchester, Grafton Street, Manchester, UK
    Eur J Endocrinol 162:1155-64. 2010
    ..Data remain divergent regarding the activational effects of endogenous hormones on adult cognitive function. We examined the association between cognition, hormones and androgen receptor (AR) CAG repeat length in a large cohort of men...
  32. ncbi Apolipoprotein E epsilon4 allele frequency in vascular dementia
    Yvonne Davidson
    Clinical Neuroscience Research Group, Greater Manchester Neurosciences Centre, Hope Hospital, Salford, UK
    Dement Geriatr Cogn Disord 22:15-9. 2006
    ..The aim of the study was to investigate whether possession of the epsilon4 allelic form of the apolipoprotein E (APOE) gene increases the risk of developing vascular dementia (VaD)...