S J Proctor

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. doi request reprint Evaluation of treatment outcome in 175 patients with Hodgkin lymphoma aged 60 years or over: the SHIELD study
    Stephen J Proctor
    Academic Haematology, Northern Institute of Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom
    Blood 119:6005-15. 2012
  2. ncbi request reprint Extreme Hodgkin's lymphoma: current problem areas
    S J Proctor
    Department of Haematological Oncology, University of Newcastle upon Tyne, UK
    Ann Oncol 17:iv15-7. 2006
  3. ncbi request reprint Hodgkin's disease in the elderly: current status and future directions
    S J Proctor
    Department of Haematology, Royal Victoria Infirmary, School of Clinical and Laboratory Sciences, Newcastle upon Tyne, UK
    Ann Oncol 13:133-7. 2002
  4. pmc Autologous bone marrow transplantation in poor-risk high-grade non-Hodgkin's lymphoma in first complete remission. Newcastle and Northern Lymphoma Group
    G H Jackson
    Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Br J Cancer 70:501-5. 1994
  5. pmc Autologous transplantation in poor risk Hodgkin's disease using high dose melphalan/etoposide conditioning with non-cryopreserved marrow rescue. The Newcastle and Northern Region Lymphoma Group
    P R Taylor
    Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Br J Cancer 67:383-7. 1993
  6. ncbi request reprint The addition of oral idarubicin to a chlorambucil/dexamethasone combination has a significant impact on time to treatment failure but none on overall survival in patients with low grade non-Hodgkin's lymphoma: Results of the Scotland and Newcastle Lymphom
    P R A Taylor
    Newcastle Hospitals Trust and Newcastle University, Newcastle upon Tyne, UK
    Leuk Lymphoma 47:2321-30. 2006
  7. ncbi request reprint Strategic approach to the management of Hodgkin's disease incorporating salvage therapy with high-dose ifosfamide, etoposide and epirubicin: a Northern Region Lymphoma Group study (UK)
    S J Proctor
    Royal Victoria Infirmary, Department of Haematology, School of Clinical and Laboratory Sciences, Newcastle upon Tyne, UK
    Ann Oncol 14:i47-50. 2003
  8. ncbi request reprint Expression and production of interleukin 4 in B-cell chronic lymphocytic leukaemia
    T Mainou-Fowler
    University Department of Haematology, School of Clinical and Laboratory Sciences, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Leuk Lymphoma 42:689-98. 2001
  9. doi request reprint Hodgkin lymphoma in the elderly: a clinical review of treatment and outcome, past, present and future
    S J Proctor
    Haematological Sciences, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, UK
    Crit Rev Oncol Hematol 71:222-32. 2009
  10. ncbi request reprint A web-based study concept designed to progress clinical research for 'orphan' disease areas in haematological oncology in the elderly: the SHIELD programme
    S J Proctor
    Academic Haematology, Medical School, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK
    Crit Rev Oncol Hematol 61:79-83. 2007

Detail Information

Publications23

  1. doi request reprint Evaluation of treatment outcome in 175 patients with Hodgkin lymphoma aged 60 years or over: the SHIELD study
    Stephen J Proctor
    Academic Haematology, Northern Institute of Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom
    Blood 119:6005-15. 2012
    ..In a Cox regression model only, obtaining CR remained significant for OS and CR plus comorbidity and age for PFS. RS-EBV status had no significant effect on outcome...
  2. ncbi request reprint Extreme Hodgkin's lymphoma: current problem areas
    S J Proctor
    Department of Haematological Oncology, University of Newcastle upon Tyne, UK
    Ann Oncol 17:iv15-7. 2006
    ....
  3. ncbi request reprint Hodgkin's disease in the elderly: current status and future directions
    S J Proctor
    Department of Haematology, Royal Victoria Infirmary, School of Clinical and Laboratory Sciences, Newcastle upon Tyne, UK
    Ann Oncol 13:133-7. 2002
    ....
  4. pmc Autologous bone marrow transplantation in poor-risk high-grade non-Hodgkin's lymphoma in first complete remission. Newcastle and Northern Lymphoma Group
    G H Jackson
    Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Br J Cancer 70:501-5. 1994
    ..It is safe and is associated with high survival when used as consolidation of CR in high-risk patients...
  5. pmc Autologous transplantation in poor risk Hodgkin's disease using high dose melphalan/etoposide conditioning with non-cryopreserved marrow rescue. The Newcastle and Northern Region Lymphoma Group
    P R Taylor
    Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Br J Cancer 67:383-7. 1993
    ..1992)...
  6. ncbi request reprint The addition of oral idarubicin to a chlorambucil/dexamethasone combination has a significant impact on time to treatment failure but none on overall survival in patients with low grade non-Hodgkin's lymphoma: Results of the Scotland and Newcastle Lymphom
    P R A Taylor
    Newcastle Hospitals Trust and Newcastle University, Newcastle upon Tyne, UK
    Leuk Lymphoma 47:2321-30. 2006
    ..The use of radiotherapy in this sub-group may have contributed to this result. CID is a potential for combination with antibody therapy particularly in older patient groups...
  7. ncbi request reprint Strategic approach to the management of Hodgkin's disease incorporating salvage therapy with high-dose ifosfamide, etoposide and epirubicin: a Northern Region Lymphoma Group study (UK)
    S J Proctor
    Royal Victoria Infirmary, Department of Haematology, School of Clinical and Laboratory Sciences, Newcastle upon Tyne, UK
    Ann Oncol 14:i47-50. 2003
    ..We conclude that the high-dose ifosfamide-containing regimens should be prospectively evaluated in the various types of non-responsive and relapsing Hodgkin's disease...
  8. ncbi request reprint Expression and production of interleukin 4 in B-cell chronic lymphocytic leukaemia
    T Mainou-Fowler
    University Department of Haematology, School of Clinical and Laboratory Sciences, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Leuk Lymphoma 42:689-98. 2001
    ..49 and r=0.76, respectively). The significant differences observed in the production of IL4 by B-CLL B- and T-lymphocytes may suggest a paracrine function of IL4 in B-CLL...
  9. doi request reprint Hodgkin lymphoma in the elderly: a clinical review of treatment and outcome, past, present and future
    S J Proctor
    Haematological Sciences, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, UK
    Crit Rev Oncol Hematol 71:222-32. 2009
    ..The SHIELD study (Study of Hodgkin lymphoma in the Elderly/Lymphoma Database) is a current example of an approach aimed at objectively defining some of the difficulties of this patient population...
  10. ncbi request reprint A web-based study concept designed to progress clinical research for 'orphan' disease areas in haematological oncology in the elderly: the SHIELD programme
    S J Proctor
    Academic Haematology, Medical School, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK
    Crit Rev Oncol Hematol 61:79-83. 2007
    ....
  11. ncbi request reprint The levels of TNF alpha, IL4 and IL10 production by T-cells in B-cell chronic lymphocytic leukaemia (B-CLL)
    T Mainou-Fowler
    Department of Haematology, School of Clinical and Laboratory Sciences, Royal Victoria Infirmary, Queen Victoria Road, New Castle upon Tyne, NE1 4 LP, UK
    Leuk Res 25:157-63. 2001
    ..The differences observed with some B-CLL cases in the production of TNF alpha, IL4 and IL10 by peripheral blood T-cells may suggest survival mechanisms for the leukaemic cells in these patients...
  12. ncbi request reprint Lymphoma presenting as a parotid tumour: a population-based study of diagnosis, treatment and outcome on behalf of the Scotland and Newcastle Lymphoma Group
    C W Tiplady
    Academic Department of Haematology, Medical School, Newcastle upon Tyne, UK
    Clin Oncol (R Coll Radiol) 16:414-9. 2004
    ....
  13. pmc Validation of the Hasford score in a demographic study in chronic granulocytic leukaemia
    M J Thomas
    University of Newcastle upon Tyne, Newcastle upon Tyne NE1 4LP, UK
    J Clin Pathol 54:491-3. 2001
    ..01)...
  14. ncbi request reprint Massive haemolysis in a group A recipient of a group O peripheral blood stem cell allogeneic transplant
    C W Tiplady
    Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Transfus Med 11:455-8. 2001
    ..The decision to revert to donor type FFP and platelets should only be made when the direct antiglobulin test is negative and the appropriate isohaemagglutinins are no longer demonstrable...
  15. ncbi request reprint Gamma-linolenic acid induces apoptosis in B-chronic lymphocytic leukaemia cells in vitro
    T Mainou-Fowler
    University Department of Haematology, School of Clinical, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK
    Leuk Lymphoma 40:393-403. 2001
    ..These results demonstrate that GLA induces apoptosis in B-CLL B- and T-cells cells in vitro and that they are more susceptible to GLA-induced apoptosis than normal peripheral blood B- and T-cells...
  16. ncbi request reprint A population-based study of intensive multi-agent chemotherapy with or without autotransplant for the highest risk Hodgkin's disease patients identified by the Scotland and Newcastle Lymphoma Group (SNLG) prognostic index. A Scotland and Newcastle Lymphom
    S J Proctor
    Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK
    Eur J Cancer 38:795-806. 2002
    ..The placing of a randomised control trial within the context of a population-based study of HD enhances the validity of the outcome...
  17. pmc Bone marrow examination in newly diagnosed Hodgkin's disease: current practice in the United Kingdom
    M R Howard
    Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Br J Cancer 71:210-2. 1995
    ..There is a significant difference in practice between clinical oncologists and haematologists, and this raises the wider issue of the influence of hospital specialisation on patient management...
  18. ncbi request reprint Somatic mitochondrial DNA mutations in adult-onset leukaemia
    L He
    Mitochondrial Research Group, School of Neurology, Neurobiology and Psychiatry, The Medical School, University of Newcastle upon Tyne, UK
    Leukemia 17:2487-91. 2003
    ..Using PCR-RFLP analysis and real-time PCR, we have studied in detail the mutation present in one patient with acute lymphatic leukaemia, demonstrating that the mutation is associated specifically with the leukaemia...
  19. ncbi request reprint Cytokine gene polymorphisms associating with severe acute graft-versus-host disease in HLA-identical sibling transplants
    P G Middleton
    Leukaemia Research Fund LRF Laboratory, Catherine Cookson Building, The Medical School, Framlington Place, Newcastle upon Tyne, UK
    Blood 92:3943-8. 1998
    ....
  20. ncbi request reprint Interleukin 4 production by peripheral blood lymphocytes in patients with classical Hodgkin lymphoma
    T Mainou-Fowler
    Department of Haematological Sciences, School of Clinical and Laboratory Sciences, Leech Building, Newcastle upon Tyne, NE2 4HH, UK
    Leuk Res 28:159-66. 2004
    ..In conclusion, there is increased production of IL4 by PHA-activated PB lymphocytes in HL. The CD3(+)CD8(+) T-cell population appears to be responsible for this increased synthesis...
  21. pmc Acute lymphoblastic leukaemia of the L3 subtype in adults in the Northern health region of England 1983-99
    M R Velangi
    Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK
    J Clin Pathol 55:591-5. 2002
    ..This paper describes a series from a population based study of 24 patients with L3 ALL presenting over 17 years...
  22. pmc Glutathione S-transferase (placental) as a marker of transformation in the human cervix uteri: an immunohistochemical study
    B J Randall
    Division of Pathology, School of Pathological Sciences, University of Newcastle upon Tyne, UK
    Br J Cancer 62:614-8. 1990
    ..Endocervical cell nuclei also showed intense nuclear staining. These findings indicate that GST is of limited use as a marker of transformation in the human cervix uteri...
  23. pmc Outcome of a risk-related therapeutic strategy used prospectively in a population-based study of Hodgkin's lymphoma in adolescents
    G L Jones
    Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne NE1 4LP, UK
    Br J Cancer 97:29-36. 2007
    ..The data suggest that older adolescents with high-risk HL require intensive protocols as primary therapy to secure optimal outcome...