J K Pritchard

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. pmc Inference of population structure using multilocus genotype data
    J K Pritchard
    Department of Statistics, University of Oxford, United Kingdom
    Genetics 155:945-59. 2000
  2. pmc Association mapping in structured populations
    J K Pritchard
    Department of Statistics, University of Oxford, United Kingdom
    Am J Hum Genet 67:170-81. 2000
  3. pmc Use of unlinked genetic markers to detect population stratification in association studies
    J K Pritchard
    Department of Statistics, University of Oxford, 1 South Parks Road, Oxford, OX1 3TG United Kingdom
    Am J Hum Genet 65:220-8. 1999
  4. pmc Linkage disequilibrium in humans: models and data
    J K Pritchard
    Department of Statistics, University of Oxford, Oxford, OX1 3TG, England
    Am J Hum Genet 69:1-14. 2001
  5. pmc Are rare variants responsible for susceptibility to complex diseases?
    J K Pritchard
    Department of Statistics, University of Oxford, 1 South Parks Road, Oxford OX1 3TG, United Kingdom
    Am J Hum Genet 69:124-37. 2001
  6. ncbi Case-control studies of association in structured or admixed populations
    J K Pritchard
    Department of Statistics, University of Oxford, Oxford, OX1 3TG, United Kingdom
    Theor Popul Biol 60:227-37. 2001

Detail Information

Publications6

  1. pmc Inference of population structure using multilocus genotype data
    J K Pritchard
    Department of Statistics, University of Oxford, United Kingdom
    Genetics 155:945-59. 2000
    ..g. , seven microsatellite loci in an example using genotype data from an endangered bird species. The software used for this article is available from http://www.stats.ox.ac.uk/ approximately pritch/home. html...
  2. pmc Association mapping in structured populations
    J K Pritchard
    Department of Statistics, University of Oxford, United Kingdom
    Am J Hum Genet 67:170-81. 2000
    ..It provides power comparable with the TDT in many settings and may substantially outperform it if there are conflicting associations in different subpopulations...
  3. pmc Use of unlinked genetic markers to detect population stratification in association studies
    J K Pritchard
    Department of Statistics, University of Oxford, 1 South Parks Road, Oxford, OX1 3TG United Kingdom
    Am J Hum Genet 65:220-8. 1999
    ..We suggest guidelines as to the number of unlinked marker loci to use...
  4. pmc Linkage disequilibrium in humans: models and data
    J K Pritchard
    Department of Statistics, University of Oxford, Oxford, OX1 3TG, England
    Am J Hum Genet 69:1-14. 2001
    ..We also outline some implications that the emerging patterns of LD have for association-mapping strategies. In particular, we discuss what marker densities might be necessary for genomewide association scans...
  5. pmc Are rare variants responsible for susceptibility to complex diseases?
    J K Pritchard
    Department of Statistics, University of Oxford, 1 South Parks Road, Oxford OX1 3TG, United Kingdom
    Am J Hum Genet 69:124-37. 2001
    ..I discuss some practical implications of these results for gene mapping efforts...
  6. ncbi Case-control studies of association in structured or admixed populations
    J K Pritchard
    Department of Statistics, University of Oxford, Oxford, OX1 3TG, United Kingdom
    Theor Popul Biol 60:227-37. 2001
    ..We discuss the statistical issues involved in the different approaches and present results from simulations comparing the relative performance of the methods under a range of models...