Research Topics
| J K PritchardSummaryAffiliation: University of Oxford Country: UK Publications
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Detail Information
Publications
Use of unlinked genetic markers to detect population stratification in association studiesJ K Pritchard
Department of Statistics, University of Oxford, 1 South Parks Road, Oxford, OX1 3TG United Kingdom
Am J Hum Genet 65:220-8. 1999..We suggest guidelines as to the number of unlinked marker loci to use...
Population growth of human Y chromosomes: a study of Y chromosome microsatellitesJ K Pritchard
Department of Biological Sciences, Stanford University
Mol Biol Evol 16:1791-8. 1999....
Association mapping in structured populationsJ K Pritchard
Department of Statistics, University of Oxford, United Kingdom
Am J Hum Genet 67:170-81. 2000..It provides power comparable with the TDT in many settings and may substantially outperform it if there are conflicting associations in different subpopulations...
Are rare variants responsible for susceptibility to complex diseases?J K Pritchard
Department of Statistics, University of Oxford, 1 South Parks Road, Oxford OX1 3TG, United Kingdom
Am J Hum Genet 69:124-37. 2001..I discuss some practical implications of these results for gene mapping efforts...
Linkage disequilibrium in humans: models and dataJ K Pritchard
Department of Statistics, University of Oxford, Oxford, OX1 3TG, England
Am J Hum Genet 69:1-14. 2001..We also outline some implications that the emerging patterns of LD have for association-mapping strategies. In particular, we discuss what marker densities might be necessary for genomewide association scans...
Case-control studies of association in structured or admixed populationsJ K Pritchard
Department of Statistics, University of Oxford, Oxford, OX1 3TG, United Kingdom
Theor Popul Biol 60:227-37. 2001..We discuss the statistical issues involved in the different approaches and present results from simulations comparing the relative performance of the methods under a range of models...
Inference of population structure using multilocus genotype dataJ K Pritchard
Department of Statistics, University of Oxford, United Kingdom
Genetics 155:945-59. 2000..g. , seven microsatellite loci in an example using genotype data from an endangered bird species. The software used for this article is available from http://www.stats.ox.ac.uk/ approximately pritch/home. html...
Distinctive genetic signatures in the Libyan JewsN A Rosenberg
Department of Biological Sciences, Stanford University, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 98:858-63. 2001..We suggest that high-resolution statistical methods that use individual multilocus genotypes may make it practical to distinguish related populations of extremely recent common ancestry...
