David J Price
Affiliation: University of Edinburgh
Caballero I, Manuel M, Molinek M, Quintana Urzainqui I, Mi D, Shimogori T, et al
. Cell-autonomous repression of Shh by transcription factor Pax6 regulates diencephalic patterning by controlling the central diencephalic organizer. Cell Rep. 2014;8:1405-18 pubmed publisher
..We conclude that Pax6's cell-autonomous repression of Shh expression around the ZLI is critical for many aspects of normal diencephalic patterning. ..
Mason J, Price D. Building brains in a dish: Prospects for growing cerebral organoids from stem cells. Neuroscience. 2016;334:105-118 pubmed publisher
Clegg J, Li Z, Molinek M, Caballero I, Manuel M, Price D. Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons. Neural Dev. 2015;10:26 pubmed publisher
Manuel M, Pratt T, Liu M, Jeffery G, Price D. Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance. BMC Dev Biol. 2008;8:59 pubmed publisher
..Here, we examined the consequences of over-expression for the eye and its axonal connections...
Fotaki V, Price D, Mason J. Newly identified patterns of Pax2 expression in the developing mouse forebrain. BMC Dev Biol. 2008;8:79 pubmed publisher
..It seems especially useful as a marker of the telencephalic septum, because of its early, strong and characteristic expression in this structure. Further, its expression is maintained in the enlarged septum of Pax6Sey/Sey mutants. ..
Pratt T, Price D. Junk DNA Used in Cerebral Cortical Evolution. Neuron. 2016;90:1141-1143 pubmed publisher
..They describe how a primate-specific long non-coding RNA titrates the levels of a microRNA that regulates an ancient signaling pathway controlling neuronal numbers. ..
Parish E, Mason J, Price D. Expression of Barhl2 and its relationship with Pax6 expression in the forebrain of the mouse embryo. BMC Neurosci. 2016;17:76 pubmed
..Repression of its expression in the thalamus and pretectum by Pax6 may be crucial for allowing proneural factors to promote normal neuronal differentiation in this region. ..
Huang Y, Mason J, Price D. Lateral cortical Cdca7 expression levels are regulated by Pax6 and influence the production of intermediate progenitors. BMC Neurosci. 2017;18:47 pubmed publisher