P M Preshaw

..The purpose of this paper is to review current thinking in periodontics with special reference to periodontal epidemiology, microbiology, and pathogenesis...

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..Research supports that downregulation of MMPs by SDD confers benefit to patients with periodontitis...

..The aim of this study was to retrospectively evaluate the role of SDD as an adjunct to scaling and root planing (SRP) in the treatment of smokers and non-smokers with CP...

..It is of concern that geriatric dentistry was not taught at all in 7% of schools. No data are available concerning whether or not geriatric dentistry is taught in the 58% non-responding schools...

..To monitor the efficacy of periodontal maintenance whether conducted in a specialist periodontology clinic or in the practice of the referring general dentist...

..The aim of this study was to further assess the role of SDD as an adjunct to scaling and root planing (SRP) in the treatment of CP...

..The aim of this pilot study was to evaluate the role of subantimicrobial dose doxycycline (SDD - 20 mg doxycycline twice daily) in the management of patients with ROAU...

..Drawing definitive conclusions is difficult, but given the lack of reliable data available, systemic antibiotics cannot be indicated as adjuncts in the treatment of chronic periodontitis...

..The aim of this study was to investigate the efficacy of SDD-40 when used as an adjunct to SRP for the treatment of periodontitis...

..To review current knowledge on cytokine interactions and the cytokine-mediated links between innate and adaptive immunity that are relevant to the pathophysiology of periodontitis...

..This narrative literature review aims to consider the impact of removable partial dentures (RPDs) on oral and systemic health...

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..Treatment of periodontitis is associated with HbA(1c) reductions of approximately 0.4%. Oral and periodontal health should be promoted as integral components of diabetes management...

..05). CONCLUSION: Quitting smoking has an additional beneficial effect in reducing probing depths following non-surgical treatment over a 12-month period...

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..To evaluate the crossover clinical trial design to assess plaque removal efficacy of the Sonicare Elite...

..There are limited data on the utility of dental professionals in providing smoking cessation counselling in the UK...

..The periodontal status of 41 medically healthy adults with untreated chronic periodontitis was monitored before and after scaling and root planing (SRP)...

..In the CAPD cohort, there were no differences in GCF-PGE2 concentrations between subgroups of smokers (n=13), ex-smokers (n=11) and non smokers (n=11). In the PDR cohort, 19/20 subjects were non-smokers...

..This pilot study aimed to investigate whether patients with aggressive periodontitis (not previously diagnosed with diabetes) have evidence of diabetes and have altered serum levels of inflammatory mediators, lipids and adipokines...

..CONCLUSION: Dental teams in primary care are aware of the importance of offering smoking cessation advice and, with further training and appropriate remuneration, could guide many of their patients who smoke to successful quit attempts...

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..VIP (10(-8)M) inhibited both IL-18 and IL-18Bpa secretion by stimulated monocytes. We conclude that IL-18 and IL-18BPa secretion by monocytes is part of the immune response to Pg, and that VIP can inhibit this process...

..To explore the possibility of using plaque weight rather than plaque index as a more objective, clinical outcome measure in periodontal clinical trials...

..Systemic antibiotics are not indicated in the vast majority of periodontal conditions encountered in general dental practice...

..Smoking, as probably the most important environmental risk factor for periodontitis, has been shown to adversely affect many neutrophil functions...

..We conclude that differences in signalling pathways activated by TLR-2 and TLR-4 ligands lead to differential innate immune responses which may be important in polymicrobial diseases such as periodontal disease...

..gingivalis and E. coli, VIP inhibited the action of both of these LPS types on monocytes. The mechanism of action of VIP on monocyte differentiation may be via inhibition of the transcription factor PU.1...

..05). PI, GI, and GCF volume did not vary in control quadrants over the course of the study (P > 0.05). Analysis of these data suggests that current OC formulations do not affect the inflammatory response of the gingiva to dental plaque...

..To examine the attitudes of dental practitioners towards specialist periodontal referral in the North East of England...

..The aim of the present study was to detect quantitative differences in selected periodontopathogens in the subgingival plaque of diabetic patients using TaqMan quantitative PCR...

..05). In conclusion, both treatments were effective in alleviating the symptoms of post-radiotherapy xerostomia, although BX achieved superiority in some of the outcomes assessed compared with OB...

..The various diseases and their treatments can have an impact upon the periodontium and the delivery of periodontal care...

..A brief synopsis of the epidemiological studies to date and their outcomes is shown in Table 1...

..g. anti-IL-18 antibodies). This review highlights the emerging data on these novel IL-1 cytokines and assesses their possible role in the pathogenesis and therapy of destructive inflammatory disorders such as RA and periodontitis...

..CRP levels have also been shown to decrease following periodontal therapy. CRP is a reliable marker of the acute phase reaction to infections and/or inflammation and is a powerful predictor of future coronary events...

..This is the first report to show the potential of VIP as an immunomodulator of Pg-stimulated inflammatory pathways in human monocytes...

..To compare the Sonicare Elite with the Sonicare Advance in terms of the reduction in supragingival plaque in the posterior, hard-to-reach areas of the mouth...

..To determine the prevalence of periodontitis in an urban population of Sri Lankans with type 2 diabetes (T2DM) and to compare the data with those from a population of adults without diabetes...

..To examine critically patients' experiences of the impact of periodontal disease on their daily lives...

..05). The treatments had similar efficacy and both can be considered effective therapies for treating dentine sensitivity...

..The relationship between osteoporosis and periodontal disease is not understood. The aim of this study was to examine the association between bone mineral density (BMD) and periodontal status in a population of Asian-American women...

..The aim of this paper is to review the existing literature regarding the Vector method...

..To assess the clinical and microbiological efficacy of chlorine dioxide (ClO2) as a topical antiseptic for the treatment of chronic atrophic candidiasis in geriatric patients...

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..The purpose of this study was to determine if a 9-month regimen of sub-antimicrobial doxycycline (20 mg, bid) had an effect on either the intestinal or the vaginal microflora...

..Although didactic teaching of geriatric dentistry has increased markedly in the last two decades, clinical experience, both intramurally and extramurally, did not keep pace...

..Xerostomia is a subjective sensation of mouth dryness that may frequently occur in older patients...