Andrew Prendergast

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. doi request reprint HIV-1 infection is characterized by profound depletion of CD161+ Th17 cells and gradual decline in regulatory T cells
    Andrew Prendergast
    Department of Paediatrics, University of Oxford, South Parks Road, Oxford, UK
    AIDS 24:491-502. 2010
  2. pmc Replicative capacity of human immunodeficiency virus type 1 transmitted from mother to child is associated with pediatric disease progression rate
    Julia G Prado
    Department of Pediatrics, University of Oxford, Oxford OX1 3SY, UK
    J Virol 84:492-502. 2010
  3. doi request reprint Factors influencing T cell activation and programmed death 1 expression in HIV-infected children
    Andrew Prendergast
    Department of Paediatrics, University of Oxford, Oxford, United Kingdom
    AIDS Res Hum Retroviruses 28:465-8. 2012
  4. doi request reprint Early virological suppression with three-class antiretroviral therapy in HIV-infected African infants
    Andrew Prendergast
    Department of Paediatrics, University of Oxford, Oxford, UK
    AIDS 22:1333-43. 2008
  5. doi request reprint Gag-specific CD4+ T-cell responses are associated with virological control of paediatric HIV-1 infection
    Andrew Prendergast
    Department of Paediatrics, University of Oxford, UK
    AIDS 25:1329-31. 2011
  6. pmc HLA footprints on human immunodeficiency virus type 1 are associated with interclade polymorphisms and intraclade phylogenetic clustering
    Philippa C Matthews
    Department of Paediatrics, Nuffield Department of Medicine, Peter Medawar Building for Pathogen Research, Oxford, United Kingdom
    J Virol 83:4605-15. 2009
  7. ncbi request reprint International perspectives, progress, and future challenges of paediatric HIV infection
    Andrew Prendergast
    Department of Paediatrics, University of Oxford, Peter Medawar Building for Pathogen Research, Oxford OX1 3SY, UK
    Lancet 370:68-80. 2007

Collaborators

Detail Information

Publications7

  1. doi request reprint HIV-1 infection is characterized by profound depletion of CD161+ Th17 cells and gradual decline in regulatory T cells
    Andrew Prendergast
    Department of Paediatrics, University of Oxford, South Parks Road, Oxford, UK
    AIDS 24:491-502. 2010
    ..The balance between pro-inflammatory Th17 and immunoregulatory Tregs may be critical in HIV pathogenesis. This study addressed changes in CD161, Th17 and Treg subsets during untreated HIV infection...
  2. pmc Replicative capacity of human immunodeficiency virus type 1 transmitted from mother to child is associated with pediatric disease progression rate
    Julia G Prado
    Department of Pediatrics, University of Oxford, Oxford OX1 3SY, UK
    J Virol 84:492-502. 2010
    ..These data underline the importance of virus-host interactions and highlight the contribution of viral attenuation through Gag-specific CD8(+) T-cell escape mutations, among other factors, in the control of pediatric HIV infection...
  3. doi request reprint Factors influencing T cell activation and programmed death 1 expression in HIV-infected children
    Andrew Prendergast
    Department of Paediatrics, University of Oxford, Oxford, United Kingdom
    AIDS Res Hum Retroviruses 28:465-8. 2012
    ..Further understanding of the factors that drive immune activation in children is critical to developing future therapeutic strategies in this population...
  4. doi request reprint Early virological suppression with three-class antiretroviral therapy in HIV-infected African infants
    Andrew Prendergast
    Department of Paediatrics, University of Oxford, Oxford, UK
    AIDS 22:1333-43. 2008
    ..Data on treatment outcome in sub-Saharan African infants exposed to single-dose nevirapine are urgently required. This feasibility study addresses efficacy of infant antiretroviral therapy in this setting...
  5. doi request reprint Gag-specific CD4+ T-cell responses are associated with virological control of paediatric HIV-1 infection
    Andrew Prendergast
    Department of Paediatrics, University of Oxford, UK
    AIDS 25:1329-31. 2011
    ..43, P < 0.001), suggesting that preservation of this cell population may be an important goal of therapeutic/vaccine strategies...
  6. pmc HLA footprints on human immunodeficiency virus type 1 are associated with interclade polymorphisms and intraclade phylogenetic clustering
    Philippa C Matthews
    Department of Paediatrics, Nuffield Department of Medicine, Peter Medawar Building for Pathogen Research, Oxford, United Kingdom
    J Virol 83:4605-15. 2009
    ..In conclusion, these data highlight the fact that HLA can be a strong selection force for both intra- and interclade HIV evolution at a population level...
  7. ncbi request reprint International perspectives, progress, and future challenges of paediatric HIV infection
    Andrew Prendergast
    Department of Paediatrics, University of Oxford, Peter Medawar Building for Pathogen Research, Oxford OX1 3SY, UK
    Lancet 370:68-80. 2007
    ....