Research Topics
Species | Chris PowerSummaryAffiliation: University College London Country: UK Publications
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Detail Information
Publications
Health and human development: understandings from life-course researchClyde Hertzman
Department of Health Care and Epidemiology, University of British Columbia, Vancouver, Canada
Dev Neuropsychol 24:719-44. 2003..Evidence demonstrating these relationships suggests that, without a consideration of early life as well as adult life experience, policies designed to improve health status tend to overlook root causes...- Childhood and adulthood psychological ill health as predictors of midlife affective and anxiety disorders: the 1958 British Birth CohortCharlotte Clark
Centre for Psychiatry, Wolfson Institute of Preventive Medicine, Queen Mary s School of Medicine and Dentistry, University of London, London EC1M 6BQ, UK
Arch Gen Psychiatry 64:668-78. 2007..Previous studies have not examined whether the risk associated with childhood psychological ill health persists for midlife psychological health... 
Are inequalities in height underestimated by adult social position? Effects of changing social structure and height selection in a cohort studyChris Power
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, London WC1N 1EH
BMJ 325:131-4. 2002..To investigate whether changing social structure and social mobility related to height generate (inflate) inequalities in height...- An intergenerational and lifecourse study of health and mortality risk in parents of the 1958 birth cohort: (II) mortality rates and study representativenessElina Hypponen
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
Public Health 119:608-15. 2005..This paper evaluates the representativeness of the study population and assesses our success in identifying the biological parents... 
Cognitive development and cortisol patterns in mid-life: findings from a British birth cohortChris Power
UCL Institute of Child Health, Centre for Paediatric Epidemiology and Biostatistics, London WC1N 1EH, UK
Psychoneuroendocrinology 33:530-9. 2008..Our results for males, but less so for females, are compatible with a causal relationship in either direction, namely from cortisol to cognitive ability or vice versa...- Body mass index throughout the life-course and blood pressure in mid-adult life: a birth cohort studyLeah Li
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, University College London, London, UK
J Hypertens 25:1215-23. 2007..The contribution of body mass index (BMI) at different life stages to adult blood pressure (BP) is not well known. We investigated whether changes in BMI across childhood and adulthood, and birthweight, influence BP in mid-adulthood... - Parental growth at different life stages and offspring birthweight: an intergenerational cohort studyElina Hypponen
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, London, UK
Paediatr Perinat Epidemiol 18:168-77. 2004..Maternal height in childhood was positively related to offspring birthweight, while the effect of her BMI was restricted to adulthood... - Health inequalities with the National Statistics-Socioeconomic classification: disease risk factors and health in the 1958 British birth cohortKate Atherton
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford Street, London, WC1N 1EH, UK
Eur J Public Health 17:486-91. 2007..We examined health inequalities for multiple disease risk factors and health outcomes, with particular reference to cardiorespiratory risk in the self-employed... - Social gradients in binge drinking and abstaining: trends in a cohort of British adultsBarbara J M H Jefferis
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
J Epidemiol Community Health 61:150-3. 2007..To investigate (1) social gradients in non-drinking and binge drinking, and (2) changes in social gradients in drinking with increasing age... - Life-time socio-economic position and cortisol patterns in mid-lifeLeah Li
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, University College London, 30 Guilford Street, London WC1N 1EH, UK
Psychoneuroendocrinology 32:824-33. 2007..Thus, our study provides evidence for effects of chronic adversity on cortisol in mid-adult life... - Hypovitaminosis D in British adults at age 45 y: nationwide cohort study of dietary and lifestyle predictorsElina Hypponen
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, London, United Kingdom
Am J Clin Nutr 85:860-8. 2007..Increased awareness of the importance of vitamin D to health has led to concerns about the prevalence of hypovitaminosis D in many parts of the world... - An intergenerational study of birthweight: investigating the birth order effectElina Hypponen
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, London, UK
BJOG 111:377-9. 2004..Our findings suggest that underlying causes of a given birthweight should be taken into account in studies that investigate long term health outcomes... - The contribution of childhood and adult socioeconomic position to adult obesity and smoking behaviour: an international comparisonChris Power
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford Street, WC1N 1EH London, UK
Int J Epidemiol 34:335-44. 2005.... - Early environment and child-to-adult growth trajectories in the 1958 British birth cohortLeah Li
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, London, United Kingdom
Am J Clin Nutr 80:185-92. 2004..Genetics and environmental conditions early in life are known to influence height. However, evidence is restricted to studies conducted at a specific age, and thus the effect on the entire growth trajectory has been neglected... - Associations of early growth and adult adiposity with patterns of salivary cortisol in adulthoodChris Power
Center for Pediatric Epidemiology and Biostatistics, Institute of Child Health, London WC1N 1EH, United Kingdom
J Clin Endocrinol Metab 91:4264-70. 2006..A suspected mediator is the hypothalamic-pituitary-adrenal axis and cortisol regulation. Our prior hypothesis was that cortisol levels are affected by anthropometry at several life stages... - Prenatal growth, BMI, and risk of type 2 diabetes by early midlifeElina Hypponen
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, London, UK
Diabetes Care 26:2512-7. 2003..small size at birth has been associated with increased risk of type 2 diabetes. Our aim was to evaluate how risk of diabetes associated with low birth weight is affected by accumulation of body mass from childhood to adulthood... - Physical (in)activity over 20 y in adulthood: associations with adult lipid levels in the 1958 British birth cohortMyung Ki
MRC Centre of Epidemiology for Child Health, Centre for Paediatric Epidemiology and Biostatistics, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
Atherosclerosis 219:361-7. 2011..To investigate associations between physical (in)activity at different life-stages and lipids in mid-adulthood, examining the role of potential confounding and mediating factors, such as adiposity... - Type 2 diabetes mellitus in midlife estimated from the Cambridge Risk Score and body mass indexClaudia Thomas
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, University College London, London, England
Arch Intern Med 166:682-8. 2006..We assessed the ability of the CRS to predict glycosylated hemoglobin (HbA(1c)) levels and determined whether the CRS was better than body mass index (BMI) at predicting HbA(1c) levels in midlife... - Life-course influences on health in British adults: effects of socio-economic position in childhood and adulthoodChris Power
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford Street, London, UK
Int J Epidemiol 36:532-9. 2007..We assess whether childhood SEP influences disease risk in mid-life, separately from the effect of adult position, and establish how associations vary across multiple measures of disease risk... - Cohort profile: 1958 British birth cohort (National Child Development Study)Chris Power
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
Int J Epidemiol 35:34-41. 2006 - Socioeconomic position in childhood and early adult life and risk of mortality: a prospective study of the mothers of the 1958 British birth cohortChris Power
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford St, London WC1N 1EH, England
Am J Public Health 95:1396-402. 2005..We sought to establish whether women's childhood socioeconomic position influenced their risk of mortality separately from the effects of adult socioeconomic position... - Sex differences in the associations between birthweight and lipid levels in middle-age: findings from the 1958 British birth cohortRachel Cooper
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, University College London, UK
Atherosclerosis 200:141-9. 2008..To examine sex differences in birthweight-lipid associations... - Obesity and type 2 diabetes risk in midadult life: the role of childhood adversityClaudia Thomas
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, University College London, 30 Guilford St, London WC1N 1EH, United Kingdom
Pediatrics 121:e1240-9. 2008.... - Changing social gradients in cigarette smoking and cessation over two decades of adult follow-up in a British birth cohortBarbara J M H Jefferis
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford Street, London WC1N 1EH
J Public Health (Oxf) 26:13-8. 2004..CONCLUSION: Conclusions Social gradients in smoking have become more marked across the lifecourse of this birth cohort. This implies continued socioeconomic inequalities in future health outcomes in a contemporary adult population... - Influences on childhood height: comparing two generations in the 1958 British birth cohortLeah Li
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
Int J Epidemiol 33:1320-8. 2004..Genetics and early environment are known to influence height, but evidence is sparse on changes in these influences over time... - Effects of grandmothers' smoking in pregnancy on birth weight: intergenerational cohort studyElina Hypponen
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, London WC1N 1EH
BMJ 327:898. 2003..To investigate the influences on birth weight of maternal smoking during pregnancy across generations... - Is there an association between hysterectomy and subsequent adiposity?Rachel Cooper
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, University College London, UK
Maturitas 58:296-307. 2007.... - Vitamin D status and glucose homeostasis in the 1958 British birth cohort: the role of obesityElina Hypponen
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guildford St, London, WC1N 1EH, UK
Diabetes Care 29:2244-6. 2006..Obesity is a well-known risk factor for vitamin D deficiency. We evaluated the interrelationship between vitamin D status, body size, and glucose homeostasis, measured by HbA1c (A1C)... - 25-Hydroxyvitamin D and pre-clinical alterations in inflammatory and hemostatic markers: a cross sectional analysis in the 1958 British Birth CohortElina Hypponen
Medical Research Council Centre for Epidemiology of Child Health and Centre for Paediatric Epidemiology and Biostatistics, University College London Institute of Child Health, London, UK
PLoS ONE 5:e10801. 2010..Our aim was to investigate the association between 25-hydroxyvitamin D [25(OH)D, a measure for vitamin D status] concentrations with pre-clinical variations in markers of inflammation and hemostasis... - Social differences in insulin-like growth factor-1: findings from a British birth cohortMeena Kumari
International Institute for Society and Health, University College London, London, UK
Ann Epidemiol 18:664-70. 2008..Our aim is to examine whether there are social differences in IGF-1 in a cohort of participants between 44 and 45 years of age... - Childhood cognition and risk factors for cardiovascular disease in midadulthood: the 1958 British Birth Cohort StudyChris Power
MRC Centre of Epidemiology for Child Health, UCL Institute of Child Health, 30 Guilford St, London, WC1N 1EH, UK
Am J Public Health 100:129-36. 2010..We sought to establish whether associations between childhood cognition and risk factors for cardiovascular disease in adulthood are explained by common causes, or adult social position or health behavior... - Intergenerational influences on childhood body mass index: the effect of parental body mass index trajectoriesLeah Li
Center for Pediatric Epidemiology and Biostatistics, UCL Institute of Child Health, London, United Kingdom
Am J Clin Nutr 89:551-7. 2009..Parental obesity in adulthood is a strong determinant of offspring obesity. Whether parental body mass index (BMI; in kg/m2) at earlier life stages is associated with offspring BMI is unknown... - Effects of socioeconomic position on inflammatory and hemostatic markers: a life-course analysis in the 1958 British birth cohortFaiza Tabassum
Department of Epidemiology and Public Health, University College London, London, United Kingdom
Am J Epidemiol 167:1332-41. 2008..Risk exposure related to SEP accumulates across the life course and contributes to raised levels of fibrinogen and C-reactive protein, while childhood SEP influences hemostatic markers more than does adult SEP... - Early life influences on adult leg and trunk length in the 1958 British birth cohortLeah Li
Centre for Pediatric Epidemiology and Biostatistics, Institute of Child Health, University College London, London, United Kingdom
Am J Hum Biol 19:836-43. 2007..Short leg length has been associated with increased disease risk. We investigated (1) whether taller childhood stature predicts longer adult leg than trunk length; (2) the effects of early life factors on adult leg/trunk length... - Child-to-adult body mass index and height trajectories: a comparison of 2 British birth cohortsLeah Li
Centre for Paediatric Epidemiology and Biostatistics Medical Research Council Centre of Epidemiology for Child Health, Institute of Child Health, University College London, 30 Guilford Street, London WC1N1EH, United Kingdom
Am J Epidemiol 168:1008-15. 2008..1% vs. 10.8% in males and 23.7% vs. 14.8% in females). Changes in height and adiposity over a relatively short period of 12 years suggest the likelihood of opposing trends of influences on later disease risk in these populations... - 25-hydroxyvitamin D, IGF-1, and metabolic syndrome at 45 years of age: a cross-sectional study in the 1958 British Birth CohortElina Hypponen
Center for Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford St, London, WC1N 1EH, UK
Diabetes 57:298-305. 2008..Physiological interactions between vitamin D and IGF-1 are reported; this is the first study to investigate their combined associations with metabolic syndrome prevalence... - Prenatal exposures and glucose metabolism in adulthood: are effects mediated through birth weight and adiposity?Claudia Thomas
Centre for Paediatric Epidemiology and Biostatistics, UCL Institute of Child Health, London, UK
Diabetes Care 30:918-24. 2007.... - Physical activity and change in body mass index from adolescence to mid-adulthood in the 1958 British cohortTessa J Parsons
Department of Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford Street, London, UK
Int J Epidemiol 35:197-204. 2006..Prevention of obesity has focused on childhood as a target period. Our aim was to assess whether frequency of adolescent physical activity affected subsequent body mass index (BMI) gain through to mid-adulthood... - The influence of birth weight and socioeconomic position on cognitive development: Does the early home and learning environment modify their effects?Chris Power
Institute of Child Health, Centre for Peadiatric Epidemiology and Biostatistics, London, United Kingdom
J Pediatr 148:54-61. 2006..To establish whether effects of birth weight and socioeconomic position on cognition are explained or modified by home or learning environments... - Longitudinal physical activity and diet patterns in the 1958 British Birth CohortTessa J Parsons
Department of Paediatric Epidemiology and Biostatistics, Institute of Child Health, London, United Kingdom
Med Sci Sports Exerc 38:547-54. 2006..We also assessed whether activity level in adulthood was influenced by activity or television viewing in adolescence or early adulthood and to examine change in diet quality and whether any change was related to change in activity level... - Fetal environment and subsequent obesity: a study of maternal smokingChris Power
Institute of Child Health, Centre for Paediatric Epidemiology and Biostatistics, 30 Guilford Street, London WC1N 1EH, UK
Int J Epidemiol 31:413-9. 2002..We studied maternal smoking during pregnancy to gain insight on how an insult affecting fetal growth might subsequently influence obesity risk through childhood to age 33... - Effects of childhood socioeconomic circumstances on persistent smokingBarbara J M H Jefferis
The Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, London, England
Am J Public Health 94:279-85. 2004..We investigated whether socioeconomic circumstances at different life stages influence persistent smoking... - Childhood adversity still matters for adult health outcomesChris Power
Institute of Child Health, WC1N 1EH, London, UK
Lancet 360:1619-20. 2002 - Socioeconomic variation in attitudes to eating and weight in female adolescentsJane Wardle
Cancer Research UK Health Behaviour Unit, University College London, London, England
Health Psychol 23:275-82. 2004..The results support the idea that socioeconomic differences in weight-related attitudes and behaviors may mediate the development of a gradient in weight... - Birth weight, childhood socioeconomic environment, and cognitive development in the 1958 British birth cohort studyBarbara J M H Jefferis
Institute of Child Health, Centre for Paediatric Epidemiology and Biostatistics, London WC1N 1EH
BMJ 325:305. 2002..5-1.5% v 2.9-12.5%). CONCLUSIONS: The postnatal environment has an overwhelming influence on cognitive function through to early adulthood, but these strong effects do not explain the weaker but independent association with birth weight... - An intergenerational and lifecourse study of health and mortality risk in parents of the 1958 birth cohort: (I) methods and tracingElina Hypponen
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
Public Health 119:599-607. 2005.... - Parental diabetes and birth weight of offspring: intergenerational cohort studyElina Hypponen
Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, London WC1N 1EH
BMJ 326:19-20. 2003 - Intergenerational obesity involves both the father and the motherTim J Cole
Am J Clin Nutr 87:1535-6; author reply 1536-7. 2008 - Disparities in psychological distress across education and sex: a longitudinal analysis of their persistence within a cohort over 19 yearsRichard Miech
Department of Health and Behavioral Sciences, University of Colorado Health Sciences Center, Denver, CO 80217, USA
Ann Epidemiol 17:289-95. 2007.... - Health selection: the role of inter- and intra-generational mobility on social inequalities in healthOrly Manor
School of Public Health and Community Medicine, The Hebrew University, Hadassah Medical Organization, PO Box 12272, Jerusalem 91120, Israel
Soc Sci Med 57:2217-27. 2003..The effect of health selection on the social gradient was variable, of modest size and cannot be regarded as a major explanation for inequalities in health in early adulthood... - Is the relation of social class to change in hearing threshold levels from childhood to middle age explained by noise, smoking, and drinking behaviour?Russell Ecob
MRC Hearing and Communication Group, School of Psychological Sciences, University of Manchester, UK
Int J Audiol 47:100-8. 2008..The magnitude of social class effect is comparable to that of occupational noise. Susceptibility to hearing impairment is likely to be appreciably determined in early childhood... - Childhood and adulthood socio-economic position and midlife depressive and anxiety disordersStephen A Stansfeld
Centre for Psychiatry, Wolfson Institute of Preventive Medicine, Barts and The London, Queen Mary s School of Medicine and Dentistry, London, UK
Br J Psychiatry 192:152-3. 2008..Effects of childhood socio-economic position on adult depressive disorders may be mediated through adult socio-economic position... - Lifecourse influences on health among British adults: effects of region of residence in childhood and adulthoodDavid P Strachan
Division of Community Health Sciences, St George s University of London, Cranmer Terrace, London, UK
Int J Epidemiol 36:522-31. 2007..We examined inter-regional migrants in Britain to evaluate the relative importance of early and recent exposures for adult cardiorespiratory risk factors, mental ill-health and sensory function... - Type 2 diabetes TCF7L2 risk genotypes alter birth weight: a study of 24,053 individualsRachel M Freathy
Institute of Biomedical and Clinical Science, Peninsula Medical School, Exeter, UK
Am J Hum Genet 80:1150-61. 2007..In conclusion, we have identified the first type 2 diabetes-susceptibility allele to be reproducibly associated with birth weight. Common gene variants can substantially influence normal birth-weight variation... - Offspring birth weight and parental mortality: prospective observational study and meta-analysisGeorge Davey Smith
Department of Social Medicine, University of Bristol, Bristol, United Kingdom
Am J Epidemiol 166:160-9. 2007..The stronger association in mothers is consistent with intergenerational effects on intrauterine growth and with the fetal origins hypothesis... - Are common symptoms in childhood associated with chronic widespread body pain in adulthood? Results from the 1958 British Birth Cohort StudyGareth T Jones
University of Aberdeen, Aberdeen, UK
Arthritis Rheum 56:1669-75. 2007..However, it is unknown whether this association persists into adulthood. The aim of the current study was to examine, prospectively, whether children with common symptoms experience an increased risk of chronic widespread pain as adults... - Socio-economic gradients in psychological distress: a focus on women, social roles and work-home characteristicsSharon Matthews
Department of Paediatric Epidemiology and Biostatics, Institute of Child Health, London, UK
Soc Sci Med 54:799-810. 2002..This surprising result therefore implicates factors beyond adult social roles examined here in the development of socio-economic gradients...