L Poller

Summary

Affiliation: University of Manchester
Country: UK

Publications

  1. ncbi International Normalized Ratios (INR): the first 20 years
    L Poller
    The University of Manchester, Manchester, UK
    J Thromb Haemost 2:849-60. 2004
  2. ncbi The effects of freeze drying and freeze drying additives on the prothrombin time and the international sensitivity index
    L Poller
    European Concerted Action on Anticoagulation, School of Biological Sciences, University of Manchester, UK
    J Clin Pathol 52:744-8. 1999
  3. ncbi European concerted action on anticoagulation. Quality assessment of the CoaguChek Mini and TAS PT-NC point-of-care whole-blood prothrombin time monitors
    Leon Poller
    European Concerted Action on Anticoagulation Central Facility, School of Biological Sciences, The University of Manchester, Manchester, United Kingdom
    Clin Chem 50:537-44. 2004
  4. ncbi Reliability of international normalised ratios from two point of care test systems: comparison with conventional methods
    Leon Poller
    European Concerted Action on Anticoagulation Central Facility, School of Biological Sciences, University of Manchester, Manchester M13 9PT
    BMJ 327:30. 2003
  5. ncbi European Concerted Action on Anticoagulation (ECAA). An assessment of lyophilised plasmas for ISI calibration of CoaguChek and TAS whole blood prothrombin time monitors
    L Poller
    ECAA Central Facility, School of Biological Sciences, The University of Manchester, Manchester M13 9PT, UK
    J Clin Pathol 56:114-9. 2003
  6. ncbi European Concerted Action on Anticoagulation (ECAA): International Normalized Ratio variability of CoaguChek and TAS point-of-care testing whole blood prothrombin time monitors
    L Poller
    ECAA Central Facility, School of Biological Sciences, The University of Manchester, Manchester, UK
    Thromb Haemost 88:992-5. 2002
  7. ncbi European Concerted Action on Anticoagulation (ECAA). Minimum number of centres for reliable International Sensitivity Index calibration of CoaguChek and TAS point-of-care whole blood monitors
    L Poller
    ECAA Central Facility, School of Biological Sciences, The University of Manchester, 3 239 Stopford Building, M13 9PT, Manchester, UK
    Thromb Res 107:61-6. 2002
  8. ncbi European Concerted Action on Anticoagulation. Evaluation of a method for International Sensitivity Index calibration of two point-of-care prothrombin time (PT) monitoring systems (CoaguChek Mini and TAS PT-NC) with fresh plasmas based on whole-blood equiv
    Leon Poller
    ECAA Central Facility, School of Biological Sciences, The University of Manchester, Manchester M13 9PT, United Kingdom
    Clin Chem 48:1672-80. 2002
  9. ncbi European Concerted Action on Anticoagulation (ECAA): multicentre international sensitivity index calibration of two types of point-of-care prothrombin time monitor systems
    L Poller
    ECAA Central Facility, School of Biological Sciences, The University of Manchester, Manchester, UK
    Br J Haematol 116:844-50. 2002
  10. ncbi European concerted action on anticoagulation. Use of plasma samples to derive international sensitivity index for whole-blood prothrombin time monitors
    Leon Poller
    European Concerted Action on Anticoagulation ECAA Central Facility, School of Biological Sciences, The University of Manchester, Manchester M13 9PT, United Kingdom
    Clin Chem 48:255-60. 2002

Detail Information

Publications22

  1. ncbi International Normalized Ratios (INR): the first 20 years
    L Poller
    The University of Manchester, Manchester, UK
    J Thromb Haemost 2:849-60. 2004
  2. ncbi The effects of freeze drying and freeze drying additives on the prothrombin time and the international sensitivity index
    L Poller
    European Concerted Action on Anticoagulation, School of Biological Sciences, University of Manchester, UK
    J Clin Pathol 52:744-8. 1999
    ....
  3. ncbi European concerted action on anticoagulation. Quality assessment of the CoaguChek Mini and TAS PT-NC point-of-care whole-blood prothrombin time monitors
    Leon Poller
    European Concerted Action on Anticoagulation Central Facility, School of Biological Sciences, The University of Manchester, Manchester, United Kingdom
    Clin Chem 50:537-44. 2004
    ..There is therefore a need for local quality assessment (QA) of the two systems...
  4. ncbi Reliability of international normalised ratios from two point of care test systems: comparison with conventional methods
    Leon Poller
    European Concerted Action on Anticoagulation Central Facility, School of Biological Sciences, University of Manchester, Manchester M13 9PT
    BMJ 327:30. 2003
    ..To find out how accurately two point of care test systems--CoaguChek Mini and TAS PT-NC (RapidPointCoag)--display international normalised ratios (INRs)...
  5. ncbi European Concerted Action on Anticoagulation (ECAA). An assessment of lyophilised plasmas for ISI calibration of CoaguChek and TAS whole blood prothrombin time monitors
    L Poller
    ECAA Central Facility, School of Biological Sciences, The University of Manchester, Manchester M13 9PT, UK
    J Clin Pathol 56:114-9. 2003
    ..The present European Concerted Action on Anticoagulation (ECAA) study aimed to assess the reliability of simpler ISI calibration using lyophilised plasma samples...
  6. ncbi European Concerted Action on Anticoagulation (ECAA): International Normalized Ratio variability of CoaguChek and TAS point-of-care testing whole blood prothrombin time monitors
    L Poller
    ECAA Central Facility, School of Biological Sciences, The University of Manchester, Manchester, UK
    Thromb Haemost 88:992-5. 2002
    ..On both brands of monitor, INR variability appeared to be due mainly to duplication differences rather than between-instrument variability on both normal and coumarin whole blood samples...
  7. ncbi European Concerted Action on Anticoagulation (ECAA). Minimum number of centres for reliable International Sensitivity Index calibration of CoaguChek and TAS point-of-care whole blood monitors
    L Poller
    ECAA Central Facility, School of Biological Sciences, The University of Manchester, 3 239 Stopford Building, M13 9PT, Manchester, UK
    Thromb Res 107:61-6. 2002
    ..The aim of the present study was to determine the number of centres required to give reliable ISI and International Normalised Ratio (INR) with these two POCT whole blood PT monitors...
  8. ncbi European Concerted Action on Anticoagulation. Evaluation of a method for International Sensitivity Index calibration of two point-of-care prothrombin time (PT) monitoring systems (CoaguChek Mini and TAS PT-NC) with fresh plasmas based on whole-blood equiv
    Leon Poller
    ECAA Central Facility, School of Biological Sciences, The University of Manchester, Manchester M13 9PT, United Kingdom
    Clin Chem 48:1672-80. 2002
    ..The use of plasma would simplify calibration of whole-blood POCT PT monitors, but important differences may exist between the ISI for whole blood and plasma calibrations...
  9. ncbi European Concerted Action on Anticoagulation (ECAA): multicentre international sensitivity index calibration of two types of point-of-care prothrombin time monitor systems
    L Poller
    ECAA Central Facility, School of Biological Sciences, The University of Manchester, Manchester, UK
    Br J Haematol 116:844-50. 2002
    ..In these circumstances, the modified WHO-type ISI calibration appeared to be satisfactory for the POCT whole-blood monitors...
  10. ncbi European concerted action on anticoagulation. Use of plasma samples to derive international sensitivity index for whole-blood prothrombin time monitors
    Leon Poller
    European Concerted Action on Anticoagulation ECAA Central Facility, School of Biological Sciences, The University of Manchester, Manchester M13 9PT, United Kingdom
    Clin Chem 48:255-60. 2002
    ....
  11. ncbi European Concerted Action on Anticoagulation--comparison of fresh plasma and whole blood multicentre ISI calibrations of CoaguChek Mini and TAS PT-NC whole blood prothrombin time point-of-care monitors
    L Poller
    European Concerted Action on Anticoagulation Central Facility, School of Biological Sciences, The University of Manchester, UK
    Thromb Haemost 87:859-66. 2002
    ..With the CoaguChek Mini system, the plasma calibration ISI can also be used to derive reliable INR with whole blood PT results. This was not possible with the TAS PT-NC system...
  12. ncbi European Concerted Action on Anticoagulation. A multicentre calibration study of WHO international reference preparations for thromboplastin, rabbit (RBT/90) and human (rTF/95)
    L Poller
    ECAA Central Facility, Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK
    J Clin Pathol 58:667-9. 2005
    ..At a theoretical INR of 3.0, the INR bias is 6.0%, and this is below the accepted 10% level of clinical relevance. Ongoing stability monitoring of World Health Organisation thromboplastin IRP is advised...
  13. ncbi European Concerted Action on Anticoagulation (ECAA): an assessment of a method for ISI calibration of two whole blood point-of-care PT monitor systems based on lyophilized plasmas using whole blood equivalent PT
    L Poller
    ECAA Central Facility, School of Biological Sciences, The University of Manchester, Manchester, UK
    J Thromb Haemost 1:766-72. 2003
    ..With the CoaguChek Mini, the correction based on the 'line of equivalence' did not improve results but was not required with this system...
  14. ncbi The prothrombin time/international normalized ratio (PT/INR) Line: derivation of local INR with commercial thromboplastins and coagulometers--two independent studies
    L Poller
    EAA Central Facility, Faculty of Life Sciences, University of Manchester, Manchester, UK
    J Thromb Haemost 9:140-8. 2011
    ....
  15. ncbi An international multicenter randomized study of computer-assisted oral anticoagulant dosage vs. medical staff dosage
    L Poller
    EAA Central Facility, Faculty of Life Sciences, University of Manchester, Manchester, UK
    J Thromb Haemost 6:935-43. 2008
    ..A multicenter clinical endpoint study has been performed to compare the safety and effectiveness of computer-assisted dosage with dosage by experienced medical staff at the same centers...
  16. ncbi Comparison of local International Sensitivity Index calibration and 'Direct INR' methods in correction of locally reported International Normalized Ratios: an international study
    L Poller
    The European Concerted Action on Anticoagulation Central Facility, University of Manchester, Faculty of Life Sciences, Manchester, UK
    J Thromb Haemost 5:1002-9. 2007
    ....
  17. ncbi Coagulometer international sensitivity index (ISI) derivation, a rapid method using the prothrombin time/international normalized ratio (PT/INR) Line: a multicenter study
    L Poller
    European Action on Anticoagulation Central Facility, Faculty of Life Sciences, University of Manchester, Manchester, UK
    J Thromb Haemost 10:1379-84. 2012
    ..These often give different international normalized ratio (INR) results from the manual method, between individual makes of instruments and with instruments from the same manufacture...
  18. ncbi More on: is there a need for replacement of the international reference preparation for thromboplastin, bovine, combined (OBT/79)?
    L Poller
    J Thromb Haemost 3:2596-8. 2005
  19. ncbi Definition of the International Normalized Ratio (INR) and its consequences for the calibration procedure of thromboplastin preparations: a rebuttal
    A M H P van den Besselaar
    J Thromb Haemost 2:1490-1; reply 1492-4. 2004
  20. ncbi The oral anticoagulant saga: past, present, and future
    B M Duxbury
    Chase Farm Hospital, Enfield, Middlesex, United Kingdom
    Clin Appl Thromb Hemost 7:269-75. 2001
    ..The last remaining problem is the limited success of doctors in achieving the therapeutic INR targets, which may be improved by computer-assisted dosage...
  21. ncbi Guidelines on preparation, certification, and use of certified plasmas for ISI calibration and INR determination
    A M H P van den Besselaar
    Hemostasis and Thrombosis Research Center, Department of Hematology, Leiden University Medical Center, The Netherlands
    J Thromb Haemost 2:1946-53. 2004
    ..Discrepant results obtained by users of certified plasmas should be reported to manufacturers or suppliers...
  22. ncbi The multiple faces of the partial thromboplastin time APTT
    S I Rapaport
    Department of Medicine and Pathology, University of California, San Diego, CA, USA
    J Thromb Haemost 2:2250-9. 2004