Steven M Pollard

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi request reprint Neural stem cells, neurons, and glia
    Steven M Pollard
    Institute for Stem Research, University of Edinburgh, Edinburgh, United Kingdom
    Methods Enzymol 418:151-69. 2006
  2. doi request reprint Fibroblast growth factor induces a neural stem cell phenotype in foetal forebrain progenitors and during embryonic stem cell differentiation
    Steven M Pollard
    Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QR, UK
    Mol Cell Neurosci 38:393-403. 2008
  3. ncbi request reprint Investigating radial glia in vitro
    Steven M Pollard
    Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, United Kingdom
    Prog Neurobiol 83:53-67. 2007
  4. doi request reprint Sox2 and Pax6 maintain the proliferative and developmental potential of gliogenic neural stem cells In vitro
    Sandra Gomez-Lopez
    Wellcome Trust Centre for Stem Cell Research and Department of Biochemistry, University of Cambridge, Cambridge, CB2 1QR, United Kingdom
    Glia 59:1588-99. 2011
  5. doi request reprint Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens
    Steven M Pollard
    Wellcome Trust Centre for Stem Cell Research and Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK
    Cell Stem Cell 4:568-80. 2009
  6. doi request reprint Imaging-based chemical screens using normal and glioma-derived neural stem cells
    Davide Danovi
    Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK
    Biochem Soc Trans 38:1067-71. 2010
  7. pmc Interplay between FGF2 and BMP controls the self-renewal, dormancy and differentiation of rat neural stem cells
    Yirui Sun
    Wellcome Trust Centre for Stem Cell Research and Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB21QR, UK
    J Cell Sci 124:1867-77. 2011
  8. doi request reprint Non-immortalized human neural stem (NS) cells as a scalable platform for cellular assays
    Lilian Hook
    Stem Cell Sciences UK Ltd, Cambridge, UK
    Neurochem Int 59:432-44. 2011
  9. ncbi request reprint Adherent neural stem (NS) cells from fetal and adult forebrain
    Steven M Pollard
    Centre Development in Stem Cell Biology, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh, King s Buildings, Edinburgh EH9 3JQ, UK
    Cereb Cortex 16:i112-20. 2006
  10. pmc Niche-independent symmetrical self-renewal of a mammalian tissue stem cell
    Luciano Conti
    Institute for Stem Cell Research, University of Edinburgh, Edinburgh, United Kingdom
    PLoS Biol 3:e283. 2005

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Neural stem cells, neurons, and glia
    Steven M Pollard
    Institute for Stem Research, University of Edinburgh, Edinburgh, United Kingdom
    Methods Enzymol 418:151-69. 2006
    ..It also reports on the current status in transfer of these approaches to human ES cells...
  2. doi request reprint Fibroblast growth factor induces a neural stem cell phenotype in foetal forebrain progenitors and during embryonic stem cell differentiation
    Steven M Pollard
    Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QR, UK
    Mol Cell Neurosci 38:393-403. 2008
    ..We speculate that the self-renewing NS cell state may be generated in vitro following transcriptional resetting induced by FGF...
  3. ncbi request reprint Investigating radial glia in vitro
    Steven M Pollard
    Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, United Kingdom
    Prog Neurobiol 83:53-67. 2007
    ..We discuss how these approaches, together with an ability to expand radial glia-like neural stem (NS) cell lines, may offer unique opportunities in basic and applied neurobiology...
  4. doi request reprint Sox2 and Pax6 maintain the proliferative and developmental potential of gliogenic neural stem cells In vitro
    Sandra Gomez-Lopez
    Wellcome Trust Centre for Stem Cell Research and Department of Biochemistry, University of Cambridge, Cambridge, CB2 1QR, United Kingdom
    Glia 59:1588-99. 2011
    ..Overall these findings indicate that Sox2 and Pax6 are both critical for self-renewal of differentiation-competent radial glia-like NS cells...
  5. doi request reprint Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens
    Steven M Pollard
    Wellcome Trust Centre for Stem Cell Research and Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK
    Cell Stem Cell 4:568-80. 2009
    ..A proof-of-principle live cell imaging-based chemical screen (450 FDA-approved drugs) identifies both differential sensitivities of GNS cells and a common susceptibility to perturbation of serotonin signaling...
  6. doi request reprint Imaging-based chemical screens using normal and glioma-derived neural stem cells
    Davide Danovi
    Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK
    Biochem Soc Trans 38:1067-71. 2010
    ..These studies provide a framework for future higher-throughput screens...
  7. pmc Interplay between FGF2 and BMP controls the self-renewal, dormancy and differentiation of rat neural stem cells
    Yirui Sun
    Wellcome Trust Centre for Stem Cell Research and Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB21QR, UK
    J Cell Sci 124:1867-77. 2011
    ....
  8. doi request reprint Non-immortalized human neural stem (NS) cells as a scalable platform for cellular assays
    Lilian Hook
    Stem Cell Sciences UK Ltd, Cambridge, UK
    Neurochem Int 59:432-44. 2011
    ..Here, we present validation and utility of a human neural lineage-restricted stem cell-based assay platform, including scale-up and automation, genetic engineering and functional characterization of differentiated progeny...
  9. ncbi request reprint Adherent neural stem (NS) cells from fetal and adult forebrain
    Steven M Pollard
    Centre Development in Stem Cell Biology, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh, King s Buildings, Edinburgh EH9 3JQ, UK
    Cereb Cortex 16:i112-20. 2006
    ..We also characterize the growth factor requirements for NS cell derivation and self-renewal. We discuss our current understanding of the relationship of NS cell lines to physiological progenitor cells of fetal and adult CNS...
  10. pmc Niche-independent symmetrical self-renewal of a mammalian tissue stem cell
    Luciano Conti
    Institute for Stem Cell Research, University of Edinburgh, Edinburgh, United Kingdom
    PLoS Biol 3:e283. 2005
    ..These homogenous cultures will enable delineation of molecular mechanisms that define a tissue-specific stem cell and allow direct comparison with pluripotent ES cells...
  11. ncbi request reprint Zebrafish mutants identify an essential role for laminins in notochord formation
    Michael J Parsons
    Division of Developmental Biology, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK
    Development 129:3137-46. 2002
    ....