Research Topics
Genomes and GenesSpecies | Kirstin PirieSummaryAffiliation: University of Oxford Country: UK Publications
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Publications
The 21st century hazards of smoking and benefits of stopping: a prospective study of one million women in the UKKirstin Pirie
Cancer Epidemiology Unit, University of Oxford, Oxford, UK
Lancet 381:133-41. 2013..Hence, only in the 21st century can we observe directly the full effects of prolonged smoking, and of prolonged cessation, on mortality among women in the UK...
Passive smoking and breast cancer in never smokers: prospective study and meta-analysisKirstin Pirie
Cancer Epidemiology Unit, University of Oxford, England
Int J Epidemiol 37:1069-79. 2008..Active smoking has little or no effect on women's risk of developing breast cancer, but it has been suggested that passive exposure to tobacco smoke may increase this risk among women who have never smoked...
Gene-environment interactions in 7610 women with breast cancer: prospective evidence from the Million Women StudyRuth C Travis
Cancer Epidemiology Unit, University of Oxford, Oxford, UK
Lancet 375:2143-51. 2010..To test for evidence of gene-environment interactions, we compared genotypic relative risks for breast cancer across the other risk factors in a large UK prospective study...
Breast cancer risk in relation to the interval between menopause and starting hormone therapyValerie Beral
University of Oxford, Oxford, OX3 7LF, UK
J Natl Cancer Inst 103:296-305. 2011..We investigated whether the timing of these therapies affected breast cancer incidence...
Factors associated with incident and fatal pancreatic cancer in a cohort of middle-aged womenRichard J Stevens
Cancer Epidemiology Unit, University of Oxford, Richard Doll Building, Roosevelt Drive, Oxford, United Kingdom
Int J Cancer 124:2400-5. 2009..22-2.03, with vs. without such a history). These factors were also associated with increased mortality from pancreatic cancer. Height, alcohol consumption and physical activity showed little or no association with pancreatic cancer risk...
Moderate alcohol intake and cancer incidence in womenNaomi E Allen
Cancer Epidemiology Unit, University of Oxford, Richard Doll Building, Oxford OX3 7LF, UK
J Natl Cancer Inst 101:296-305. 2009..With the exception of breast cancer, little is known about the effect of moderate intakes of alcohol, or of particular types of alcohol, on cancer risk in women...
Hormone replacement therapy and incidence of central nervous system tumours in the Million Women StudyVictoria S Benson
Cancer Epidemiology Unit, University of Oxford, Oxford, United Kingdom
Int J Cancer 127:1692-8. 2010..97, 95% CI: 0.82-1.16) (heterogeneity p < 0.001). Among current users of oestrogen-only and oestrogen-progestagen HRT, there was no significant heterogeneity by duration of use, hormonal constituent or mode of administration of HRT...
Body mass index and risk of liver cirrhosis in middle aged UK women: prospective studyBette Liu
Cancer Epidemiology Unit, University of Oxford, Oxford OX3 7LF
BMJ 340:c912. 2010..To determine the relation between body mass index (BMI) and liver cirrhosis and the contribution that BMI and alcohol consumption make to the incidence of liver cirrhosis in middle aged women in the UK...
Height and cancer incidence in the Million Women Study: prospective cohort, and meta-analysis of prospective studies of height and total cancer riskJane Green
Cancer Epidemiology Unit, University of Oxford, UK
Lancet Oncol 12:785-94. 2011....
Fluid intake and incidence of renal cell carcinoma in UK womenN E Allen
Cancer Epidemiology Unit, Nuffield Department of Clinical Medicine, University of Oxford, Richard Doll Building, Roosevelt Drive, Oxford OX3 7LF, UK
Br J Cancer 104:1487-92. 2011..We assessed the association between intakes of total fluids and of specific beverages on the risk of renal cell carcinoma in a large prospective cohort of UK women...
Body mass index and physical activity in relation to the incidence of hip fracture in postmenopausal womenMiranda E G Armstrong
Cancer Epidemiology Unit, University of Oxford, Oxford, United Kingdom
J Bone Miner Res 26:1330-8. 2011..68 (95% CI 0.62-0.75), with similar results for strenuous exercise. In this large cohort of postmenopausal women, BMI and physical activity had independent effects on hip fracture risk...
Comparison of the effects of genetic and environmental risk factors on in situ and invasive ductal breast cancerGillian K Reeves
University of Oxford, Oxford, UK
Int J Cancer 131:930-7. 2012..The lack of association between BMI and DCIS suggests a greater influence of BMI on disease progression...
Reproductive factors and specific histological types of breast cancer: prospective study and meta-analysisG K Reeves
Cancer Epidemiology Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
Br J Cancer 100:538-44. 2009..The effect of menopause did not vary significantly by tumour histology. Meta-analysis of published results on the effects of age at menarche and age at first birth on ductal and lobular cancers were in keeping with our findings...
Reproductive history and pancreatic cancer incidence and mortality in a cohort of postmenopausal womenRichard J Stevens
Department of Primary Health Care, Oxford, OX3 7LF, UK
Cancer Epidemiol Biomarkers Prev 18:1457-60. 2009..Any effect of reproductive history and pancreatic cancer risk in women is likely to be weak, if it exists at all...
Incidence of breast cancer and its subtypes in relation to individual and multiple low-penetrance genetic susceptibility lociGillian K Reeves
Cancer Epidemiology Unit, University of Oxford, Oxford, United Kingdom
JAMA 304:426-34. 2010..There is limited evidence on how the risk of breast cancer and its subtypes depend on low-penetrance susceptibility loci, individually or in combination...
Reported frequency of physical activity in a large epidemiological study: relationship to specific activities and repeatability over timeMiranda E G Armstrong
Cancer Epidemiology Unit, University of Oxford, Richard Doll Building, Old Road Campus, Oxford OX3 7LF, UK
BMC Med Res Methodol 11:97. 2011..We examine the relationships between various physical activities self-reported at different times in a large cohort study of middle-aged UK women...
Cancer incidence and mortality in relation to body mass index in the Million Women Study: cohort studyGillian K Reeves
Cancer Epidemiology Unit, University of Oxford, Oxford OX3 7LF
BMJ 335:1134. 2007..To examine the relation between body mass index (kg/m2) and cancer incidence and mortality...
Family history and breast cancer tumour characteristics in screened womenElisabeth Couto
Cancer Epidemiology Unit, Richard Doll Building, University of Oxford, Oxford, UK
Int J Cancer 123:2950-4. 2008..There was no significant difference in the RR of screen-detected breast cancer associated with a family history of the disease according to invasiveness, size, nodal status, malignancy grade or morphological type of the breast cancer...
Duration and magnitude of the postoperative risk of venous thromboembolism in middle aged women: prospective cohort studySian Sweetland
Cancer Epidemiology Unit, University of Oxford, Richard Doll Building, Oxford OX3 7LF
BMJ 339:b4583. 2009..To examine the duration and magnitude of increased risk of venous thromboembolism after different types of surgery...
Lifestyle factors and primary glioma and meningioma tumours in the Million Women Study cohortV S Benson
Cancer Epidemiology Unit, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
Br J Cancer 99:185-90. 2008..In conclusion, for women in the United Kingdom, the incidence of glioma or meningioma tumours increases with increasing height and increasing BMI...
