F Broughton Pipkin

Summary

Affiliation: University of Nottingham
Country: UK

Publications

  1. pmc Pilot study for a trial of ursodeoxycholic acid and/or early delivery for obstetric cholestasis
    Vinita Gurung
    School of Clinical Sciences, Division of Human Development, University of Nottingham, Nottingham, UK
    BMC Pregnancy Childbirth 9:19. 2009
  2. ncbi Angiotensin II has depressor effects in pregnant and nonpregnant women
    F Broughton Pipkin
    Department of Obstetrics and Gynecology, Queen s Medical Centre, University Hospital, Nottingham, England
    Hypertension 30:1247-52. 1997
  3. ncbi Predicting high blood pressure in pregnancy: a multivariate approach
    F Broughton Pipkin
    Department of Obstetrics and Gynaecology, Nottingham University School of Medicine, Nottinghamshire, UK
    J Hypertens 16:221-9. 1998
  4. ncbi What is the place of genetics in the pathogenesis of pre-eclampsia?
    F Broughton Pipkin
    School of Human Development, University Hospital, Nottingham, UK
    Biol Neonate 76:325-30. 1999
  5. doi Smoking in moderate/severe preeclampsia worsens pregnancy outcome, but smoking cessation limits the damage
    F Broughton Pipkin
    Department of Obstetrics and Gynaecology, Maternity Unit, City Hospital, Nottingham NG5 1PB, United Kingdom
    Hypertension 51:1042-6. 2008
  6. ncbi Maternal endocrine adaptation throughout pregnancy to nutritional manipulation: consequences for maternal plasma leptin and cortisol and the programming of fetal adipose tissue development
    J Bispham
    Academic Division of Child Health, School of Human Development, University Hospital, Nottingham NG7 2UH, United Kingdom
    Endocrinology 144:3575-85. 2003
  7. ncbi Angiotensin-converting enzyme insertion-deletion polymorphism in normotensive and pre-eclamptic pregnancies
    L Morgan
    Clinical Chemistry Division, School of Clinical Laboratory Sciences, University Hospital, Nottingham, UK
    J Hypertens 17:765-8. 1999
  8. ncbi Autoradiographic determination of angiotensin II receptors in prepubertal and postpubertal pig ovarian tissue
    G Shuttleworth
    Division of Obstetrics and Gynaecology, School of Human Development, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK
    Reproduction 122:701-10. 2001
  9. ncbi Polymorphism in oestrogen response element associated with variation in plasma angiotensinogen concentrations in healthy pregnant women
    L Morgan
    Clinical Chemistry Division, School of Clinical Laboratory Sciences, University Hospital, Nottingham, UK
    J Hypertens 18:553-7. 2000
  10. ncbi The localization and expression of the renin-angiotensin system in the human placenta throughout pregnancy
    A C Cooper
    Division of Obstetrics and Gynaecology, School of Human Development, Queen s Medical Centre, Nottingham, NG7 2UH, UK
    Placenta 20:467-74. 1999

Collaborators

Detail Information

Publications13

  1. pmc Pilot study for a trial of ursodeoxycholic acid and/or early delivery for obstetric cholestasis
    Vinita Gurung
    School of Clinical Sciences, Division of Human Development, University of Nottingham, Nottingham, UK
    BMC Pregnancy Childbirth 9:19. 2009
    ..The trial is funded by the NHS Research for Patient Benefit (RfPB) Programme...
  2. ncbi Angiotensin II has depressor effects in pregnant and nonpregnant women
    F Broughton Pipkin
    Department of Obstetrics and Gynecology, Queen s Medical Centre, University Hospital, Nottingham, England
    Hypertension 30:1247-52. 1997
    ..This might mediate the depressor effect. In conclusion, the diminished pressor response to angiotensin II in normal pregnancy may be partly due to an increasing depressor effect of the hormone...
  3. ncbi Predicting high blood pressure in pregnancy: a multivariate approach
    F Broughton Pipkin
    Department of Obstetrics and Gynaecology, Nottingham University School of Medicine, Nottinghamshire, UK
    J Hypertens 16:221-9. 1998
    ..To identify predictors of pregnancy-induced hypertension and pre-eclampsia in 212 nulliparous women before 20 weeks' gestation and at approximately 28 weeks' gestation...
  4. ncbi What is the place of genetics in the pathogenesis of pre-eclampsia?
    F Broughton Pipkin
    School of Human Development, University Hospital, Nottingham, UK
    Biol Neonate 76:325-30. 1999
    ..It is hoped that funding will become available this year in the UK to allow the collection of such a database. The introduction of chip technology should allow genome scanning of the resource...
  5. doi Smoking in moderate/severe preeclampsia worsens pregnancy outcome, but smoking cessation limits the damage
    F Broughton Pipkin
    Department of Obstetrics and Gynaecology, Maternity Unit, City Hospital, Nottingham NG5 1PB, United Kingdom
    Hypertension 51:1042-6. 2008
    ....
  6. ncbi Maternal endocrine adaptation throughout pregnancy to nutritional manipulation: consequences for maternal plasma leptin and cortisol and the programming of fetal adipose tissue development
    J Bispham
    Academic Division of Child Health, School of Human Development, University Hospital, Nottingham NG7 2UH, United Kingdom
    Endocrinology 144:3575-85. 2003
    ..These changes may result in the offspring of NR mothers being at increased risk of obesity in later life...
  7. ncbi Angiotensin-converting enzyme insertion-deletion polymorphism in normotensive and pre-eclamptic pregnancies
    L Morgan
    Clinical Chemistry Division, School of Clinical Laboratory Sciences, University Hospital, Nottingham, UK
    J Hypertens 17:765-8. 1999
    ..To investigate the hypothesis that pre-eclampsia is associated with a common insertion-deletion polymorphism in the angiotensin-converting enzyme gene...
  8. ncbi Autoradiographic determination of angiotensin II receptors in prepubertal and postpubertal pig ovarian tissue
    G Shuttleworth
    Division of Obstetrics and Gynaecology, School of Human Development, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK
    Reproduction 122:701-10. 2001
    ..In summary, these results indicate that angiotensin II receptors are of higher affinity in postpubertal tissue than they are in prepubertal tissue, and indicate an active renin-angiotensin system within the pig ovary...
  9. ncbi Polymorphism in oestrogen response element associated with variation in plasma angiotensinogen concentrations in healthy pregnant women
    L Morgan
    Clinical Chemistry Division, School of Clinical Laboratory Sciences, University Hospital, Nottingham, UK
    J Hypertens 18:553-7. 2000
    ....
  10. ncbi The localization and expression of the renin-angiotensin system in the human placenta throughout pregnancy
    A C Cooper
    Division of Obstetrics and Gynaecology, School of Human Development, Queen s Medical Centre, Nottingham, NG7 2UH, UK
    Placenta 20:467-74. 1999
    ..These results clearly show the expression of a majority of the components of the RAS in the placenta from early gestation onwards. Therefore, these results suggest that the RAS may have a role in the human placenta throughout gestation...
  11. doi Expression of AT1R, AT2R and AT4R and their roles in extravillous trophoblast invasion in the human
    P J Williams
    School of Clinical Sciences, University of Nottingham, City Hospital Nottingham, Nottingham NG5 1PB, United Kingdom
    Placenta 31:448-55. 2010
    ..This study has characterised expression of AT4R and AT1R and AT2R in human placenta throughout normal pregnancy and in PE. Both AngIV and AngII may play an important role in normal pregnancy...
  12. ncbi The effects of pregnancy and maternal nutrition on the maternal renin-angiotensin system in sheep
    J Dandrea
    Academic Division of Child Health, School of Human Development, University Hospital, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Exp Physiol 87:353-9. 2002
    ..Following the restoration of maternal diet after 80 days gestation, PRC gradually rose to peak at term. These adaptations in the maternal RAS during the critical period of placental growth may have long-term effects on fetal development...
  13. ncbi In vitro development of pig preantral follicles cultured in a serum-free medium and the effect of angiotensin II
    G Shuttleworth
    Division of Obstetrics and Gynaecology, School of Human Development, The University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Reproduction 123:807-18. 2002
    ....