Phillips R, Al Zamil H, Hunt L, Fortier M, Lopez Bernal A. Genes for prostaglandin synthesis, transport and inactivation are differentially expressed in human uterine tissues, and the prostaglandin F synthase AKR1B1 is induced in myometrial cells by inflammatory cytokines. Mol Hum Reprod. 2011;17:1-13 pubmed publisher
..In cultured myometrial cells, there was a dose-dependent stimulatory effect of interleukin 1? and tumour necrosis factor ? on PTGS2, PTGES and AKR1B1 (PGF synthase) expression. ..