Research Topics
| Gabriel G PerronSummaryAffiliation: University of Oxford Country: UK Publications
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Detail Information
Publications
Source-sink dynamics shape the evolution of antibiotic resistance and its pleiotropic fitness costGabriel G Perron
Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
Proc Biol Sci 274:2351-6. 2007....
Parallel evolution of multidrug-resistance in Salmonella enterica isolated from swineGabriel G Perron
Department of Biology, McGill University, Montreal, QC, Canada
FEMS Microbiol Lett 281:17-22. 2008....
A reservoir of drug-resistant pathogenic bacteria in asymptomatic hostsGabriel G Perron
Department of Biology, McGill University, Montreal, Quebec, Canada
PLoS ONE 3:e3749. 2008..This study shows how agricultural practice and human intervention may lead and influence the evolution of a hidden reservoir of pathogens, with important implications for human health...
Genotypic diversity and antimicrobial resistance in asymptomatic Salmonella enterica serotype Typhimurium DT104Gabriel G Perron
Department of Biology, McGill University, 1205 Avenue Dr Penfield, Montreal, H3A 1B1 Que, Canada
Infect Genet Evol 7:223-8. 2007..We thus concluded that an important aspect of Salmonella population structure and ecology is overlooked in investigations of disease-associated isolates...
Hypermutability and compensatory adaptation in antibiotic-resistant bacteriaGabriel G Perron
Department of Zoology, University of Oxford, United Kingdom
Am Nat 176:303-11. 2010..These results suggest that selection for mutations that offset the fitness cost associated with antibiotic resistance may help to explain the high frequency of mutator bacteria and antibiotic resistance observed in chronic infections...
The population genetics of antibiotic resistance: integrating molecular mechanisms and treatment contextsR Craig MacLean
Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
Nat Rev Genet 11:405-14. 2010..However, putting these models to practical use will require extensive collaboration between mathematicians, molecular biologists, evolutionary ecologists and clinicians...
The evolution of antibiotic resistance: insight into the roles of molecular mechanisms of resistance and treatment contextR Craig MacLean
Institution Department of Zoology, University of Oxford, UK
Discov Med 10:112-8. 2010....
Experimental evolution of resistance to an antimicrobial peptideGabriel G Perron
Department of Biology, McGill University, 1205 Avenue Dr Penfield, Montreal, Que H3A 1B1, Canada
Proc Biol Sci 273:251-6. 2006....
Host mixing and disease emergenceRebecca Benmayor
Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
Curr Biol 19:764-7. 2009..These results suggest that adaptation to novel hosts can occur only under very specific ecological conditions, and that small changes in contact rates between host species might help to mitigate disease emergence...
