Kirsten P Perrett

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi Towards an improved serogroup B Neisseria meningitidis vaccine
    Kirsten P Perrett
    Oxford Vaccine Group, Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Headington, Oxford, OX3 7LJ, UK
    Expert Opin Biol Ther 5:1611-25. 2005
  2. ncbi Immunogenicity and immune memory of a nonadjuvanted quadrivalent meningococcal glycoconjugate vaccine in infants
    Kirsten P Perrett
    Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Centre for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, UK
    Pediatr Infect Dis J 28:186-93. 2009
  3. ncbi Immunogenicity of a tetravalent meningococcal glycoconjugate vaccine in infants: a randomized controlled trial
    Matthew D Snape
    Oxford Vaccine Group, University of Oxford, England
    JAMA 299:173-84. 2008
  4. ncbi Plasma and memory B-cell kinetics in infants following a primary schedule of CRM 197-conjugated serogroup C meningococcal polysaccharide vaccine
    Dominic F Kelly
    Oxford Vaccine Group, Department of Paediatrics, Oxford University, Oxford, UK
    Immunology 127:134-43. 2009
  5. ncbi B cell memory to a serogroup C meningococcal conjugate vaccine in childhood and response to booster: little association with serum IgG antibody
    Kirsten P Perrett
    Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford OX3 7LE, United Kingdom
    J Immunol 189:2673-81. 2012
  6. ncbi Maintaining protection against invasive bacteria with protein-polysaccharide conjugate vaccines
    Andrew J Pollard
    Department of Paediatrics, University of Oxford, Level 2, Children s Hospital, Oxford, UK
    Nat Rev Immunol 9:213-20. 2009
  7. ncbi Single nucleotide polymorphisms in the Toll-like receptor 3 and CD44 genes are associated with persistence of vaccine-induced immunity to the serogroup C meningococcal conjugate vaccine
    Catrin E Moore
    Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom
    Clin Vaccine Immunol 19:295-303. 2012

Detail Information

Publications7

  1. ncbi Towards an improved serogroup B Neisseria meningitidis vaccine
    Kirsten P Perrett
    Oxford Vaccine Group, Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Headington, Oxford, OX3 7LJ, UK
    Expert Opin Biol Ther 5:1611-25. 2005
    ..Investment by the pharmaceutical industry in preclinical research and development provides hope that an efficacious serogroup B meningococcal vaccine can be developed...
  2. ncbi Immunogenicity and immune memory of a nonadjuvanted quadrivalent meningococcal glycoconjugate vaccine in infants
    Kirsten P Perrett
    Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Centre for Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, UK
    Pediatr Infect Dis J 28:186-93. 2009
    ..We evaluated the immunogenicity and reactogenicity of a novel quadrivalent nonadjuvanted meningococcal glycoconjugate vaccine (MenACWY-CRM) in healthy infants...
  3. ncbi Immunogenicity of a tetravalent meningococcal glycoconjugate vaccine in infants: a randomized controlled trial
    Matthew D Snape
    Oxford Vaccine Group, University of Oxford, England
    JAMA 299:173-84. 2008
    ..However, the currently licensed vaccine is poorly immunogenic in infancy, when the highest rates of disease are observed...
  4. ncbi Plasma and memory B-cell kinetics in infants following a primary schedule of CRM 197-conjugated serogroup C meningococcal polysaccharide vaccine
    Dominic F Kelly
    Oxford Vaccine Group, Department of Paediatrics, Oxford University, Oxford, UK
    Immunology 127:134-43. 2009
    ..This study provides data on B-cell kinetics following a primary schedule of immunization in young infants upon which to base further studies of the underlying cellular mechanism of humoral immunity...
  5. ncbi B cell memory to a serogroup C meningococcal conjugate vaccine in childhood and response to booster: little association with serum IgG antibody
    Kirsten P Perrett
    Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford OX3 7LE, United Kingdom
    J Immunol 189:2673-81. 2012
    ..Measurement of B cell memory in peripheral blood does not predict steady state Ab levels nor the capacity to respond to a booster dose of MenC Ag...
  6. ncbi Maintaining protection against invasive bacteria with protein-polysaccharide conjugate vaccines
    Andrew J Pollard
    Department of Paediatrics, University of Oxford, Level 2, Children s Hospital, Oxford, UK
    Nat Rev Immunol 9:213-20. 2009
    ..In this Science and Society article, we describe how vaccine-induced immunity wanes rapidly after vaccination in early childhood and argue that strategies that sustain protection in the population must be considered...
  7. ncbi Single nucleotide polymorphisms in the Toll-like receptor 3 and CD44 genes are associated with persistence of vaccine-induced immunity to the serogroup C meningococcal conjugate vaccine
    Catrin E Moore
    Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom
    Clin Vaccine Immunol 19:295-303. 2012
    ..These results suggest that genetic polymorphisms in the TLR3 and CD44 genes are associated with the persistence of the immune response to MenC vaccines 1 to 6 years after vaccination...