Tina Perica

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. doi request reprint Ubiquitin--molecular mechanisms for recognition of different structures
    Tina Perica
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 OQH, UK
    Curr Opin Struct Biol 20:367-76. 2010
  2. pmc Evolution of oligomeric state through geometric coupling of protein interfaces
    Tina Perica
    Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 OQH, United Kingdom
    Proc Natl Acad Sci U S A 109:8127-32. 2012

Detail Information

Publications2

  1. doi request reprint Ubiquitin--molecular mechanisms for recognition of different structures
    Tina Perica
    MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 OQH, UK
    Curr Opin Struct Biol 20:367-76. 2010
    ..The accommodation of differences in binding proteins is enabled by changes in the flexible surface side chains, loop movements, different specific interactions, water molecules in the interface and the flexible C-terminus...
  2. pmc Evolution of oligomeric state through geometric coupling of protein interfaces
    Tina Perica
    Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 OQH, United Kingdom
    Proc Natl Acad Sci U S A 109:8127-32. 2012
    ..We find that such indirect, or allosteric mutations affecting intersubunit geometry via indirect mechanisms are as important as interface sequence changes for evolution of oligomeric states...