Affiliation: University of Cambridge
- Ubiquitin--molecular mechanisms for recognition of different structuresTina Perica
MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 OQH, UK
Curr Opin Struct Biol 20:367-76. 2010..The accommodation of differences in binding proteins is enabled by changes in the flexible surface side chains, loop movements, different specific interactions, water molecules in the interface and the flexible C-terminus...
- Environmental shaping of codon usage and functional adaptation across microbial communitiesMasa Roller
Bioinformatics Group, Department of Molecular Biology, Faculty of Science, University of Zagreb, Horvatovac 102a, 10000 Zagreb, Croatia, Institute of Biochemistry, Biological Research Centre of the Hungarian Academy of Sciences, Temesvari korut 62, H 6726 Szeged, Hungary, MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK and Department of Informatics, University of Oslo, PO Box 1080 Blindern, NO 0316 Oslo, Norway
Nucleic Acids Res 41:8842-52. 2013..Our results provide valuable arguments in defining the concept of microbial species through the context of their interactions within the community. ..
- Evolution of oligomeric state through geometric coupling of protein interfacesTina Perica
Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 OQH, United Kingdom
Proc Natl Acad Sci U S A 109:8127-32. 2012..We find that such indirect, or allosteric mutations affecting intersubunit geometry via indirect mechanisms are as important as interface sequence changes for evolution of oligomeric states...