Research Topics
| Stephanie PellegrinSummaryAffiliation: University of Bristol Country: UK Publications
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Detail Information
Publications
The Rho family GTPase Rif induces filopodia through mDia2Stephanie Pellegrin
Mammalian Cell Biology Laboratory, Department of Biochemistry, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, United Kingdom
Curr Biol 15:129-33. 2005..Thus, Rif and Cdc42 represent two distinct routes to the induction of filopodia-producing structures with both shared and unique properties...
Actin stress fibresStephanie Pellegrin
Department of Biochemistry, School of Medical Sciences, University of Bristol, BS8 1TD, UK
J Cell Sci 120:3491-9. 2007..Some of these structures are less suited for cell motility and more suited to static contraction. In keeping with this, many specialised contractile cell types use stress fibres to remodel tissues and extracellular matrix...
Critical band 3 multiprotein complex interactions establish early during human erythropoiesisTimothy J Satchwell
School of Biochemistry, University of Bristol, Bristol, UK
Blood 118:182-91. 2011..These data are consistent with assembly of major components of the band 3 macrocomplex at an early stage during erythropoiesis...
The small GTPase Rif is an alternative trigger for the formation of actin stress fibers in epithelial cellsLifei Fan
Department of Biochemistry, School of Medical Sciences, University Walk, University of Bristol, Bristol BS8 1TD, UK
J Cell Sci 123:1247-52. 2010..This study establishes Rif as a general regulator of Diaphanous-related formins and shows how non-classical Rho family members can access classical Rho pathways to create new signaling interfaces in cytoskeletal regulation...
Synergistic roles for the Map and Tir effector molecules in mediating uptake of enteropathogenic Escherichia coli (EPEC) into non-phagocytic cellsMark A Jepson
Department of Biochemistry, School of Medical Sciences, University Walk, Bristol, BS8 1TD, UK
Cell Microbiol 5:773-83. 2003..This synergism, which is in stark contrast to the antagonistic actions of Map and Tir in regulating filopodia and pedestal formation, further illustrates the complex interplay between EPEC effectors...
Rho GTPase activation assaysStephanie Pellegrin
Mammalian Cell Biology Laboratory, Department of Biochemistry, School of Medical Sciences, University of Bristol, United Kingdom
Curr Protoc Cell Biol . 2008..This unit describes the techniques for preparing the reagents required for assays of RhoA, Rac, and Cdc42 and gives practical tips for the successful application of the assay in a range of situations...
Scanning electron microscopy of cell surface morphologySamantha Passey
Mammalian Cell Biology Laboratory, Department of Biochemistry, School of Medical Sciences, University of Bristol, United Kingdom
Curr Protoc Cell Biol . 2007..Here we highlight the critical factors in sample preparation to ensure optimal high-resolution imaging of the surface of mammalian cells and tissues...
Investigating the key membrane protein changes during in vitro erythropoiesis of protein 4.2 (-) cells (mutations Chartres 1 and 2)Emile van den Akker
Department of Biochemistry, School of Medical Sciences, University Walk, Bristol, UK
Haematologica 95:1278-86. 2010..We decided to investigate at which stage of erythropoiesis these hallmarks of protein 4.2 deficiency arise in a novel protein 4.2 patient and whether they cause disruption to the band 3 macrocomplex...
