Giles J Peek
Affiliation: University Hospitals of Leicester
- CESAR: conventional ventilatory support vs extracorporeal membrane oxygenation for severe adult respiratory failureGiles J Peek
Department of Cardiothoracic Surgery, Glenfield Hospital, Groby Road, Leicester, LE3 9QP, UK
BMC Health Serv Res 6:163. 2006....
- Modular extracorporeal life support for multiorgan failure patientsGiles J Peek
Division of Cardiac Surgery, University of Leicester, Glenfield Hospital, UK
Liver 22:69-71. 2002..All patients would have been expected to die according to our previous experience. We believe that MARS may prove a useful therapy for patients with MSOF...
- Methods of data collection and analysis for the economic evaluation alongside a national, multi-centre trial in the UK: conventional ventilation or ECMO for Severe Adult Respiratory Failure (CESAR)Mariamma M Thalanany
School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, NR4 7TJ, UK
BMC Health Serv Res 8:94. 2008..Given the high cost of treatment, ECMO is considered an expensive technology for many funding systems. However, conventional treatment for severe respiratory failure is also one of the more costly forms of care in any health system...
- Efficacy and economic assessment of conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure (CESAR): a multicentre randomised controlled trialGiles J Peek
Department of Cardiothoracic Surgery, Glenfield Hospital, Leicester, UK
Lancet 374:1351-63. 2009..We aimed to delineate the safety, clinical efficacy, and cost-effectiveness of extracorporeal membrane oxygenation (ECMO) compared with conventional ventilation support...
- A potential propensity for failure secondary to clot embolism in neonatal ECMOEspeed Khoshbin
Division of Cardiac Surgery, University of Leicester Heart Link ECMO Centre, Glenfield Hospital, Leicester, UK
Perfusion 20:177-81. 2005..To report a single case of oxygenator failure caused by clot embolism originating from the bladder; and to discuss some preventative options...
- A comparison of radiographic signs of pulmonary inflammation during ECMO between silicon and poly-methyl pentene oxygenatorsEspeed Khoshbin
Division of Cardiac Surgery Heart Link ECMO Centre, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK
Perfusion 22:15-21. 2007..The inflammatory process affects all areas of the lung, even areas previously spared by the primary disease...
- Performance of polymethyl pentene oxygenators for neonatal extracorporeal membrane oxygenation: a comparison with silicone membrane oxygenatorsEspeed Khoshbin
Division of Cardiac Surgery and Heart Link ECMO Centre, Glenfield University Hospital, Leicester, UK
Perfusion 20:129-34. 2005....
- Experience with mobile inhaled nitric oxide during transport of neonates and children with respiratory insufficiency to an extracorporeal membrane oxygenation centerClaire Westrope
Heartlink ECMO Centre, Glenfield Hospital, Leicester, UK
Pediatr Crit Care Med 5:542-6. 2004....
- Referral to an extracorporeal membrane oxygenation center and mortality among patients with severe 2009 influenza A(H1N1)Moronke A Noah
Heartlink ECMO Centre, Glenfield Hospital, Leicester, England
JAMA 306:1659-68. 2011..ECMO was used to treat patients with ARDS during the 2009 influenza A(H1N1) pandemic...
- Extracorporeal membrane oxygenation for chickenpox pneumonia: a single institution's experienceRalph W White
Heartlink ECMO Centre, Department of Cardiothoracic Surgery, Glenfield Hospital, Leicester, United Kingdom
ASAIO J 49:378-82. 2003..Pneumonia as a complication of chickenpox can rapidly become severe and life threatening. Extracorporeal respiratory support may be helpful in patients refractory to conventional ventilation...
- Panton-Valentine leukocidin expressing Staphylococcus aureus pneumonia managed with extracorporeal membrane oxygenation: experience and outcomeMoronke A Noah
Heart Link ECMO Unit, Glenfield General Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK
Crit Care Med 38:2250-3. 2010..aureus pneumonia with extracorporeal membrane oxygenation support. As a large extracorporeal membrane oxygenation center, we reviewed our experience and outcomes with Panton-Valentine Leukocidin expressing S. aureus pneumonia...
- Factors influencing the outcome of paediatric cardiac surgical patients during extracorporeal circulatory supportSendhil K Balasubramanian
Department of ECMO, Glenfield General Hospital, Leicester, LE3 9QQ, UK
J Cardiothorac Surg 2:4. 2007..We assessed the outcome of children who had ECMO following repair of congenital cardiac defects (CCD) and identified the risk factors associated with hospital mortality...
- Poly-methyl pentene oxygenators have improved gas exchange capability and reduced transfusion requirements in adult extracorporeal membrane oxygenationEspeed Khoshbin
Division of Cardiac Surgery, University of Leicester, and the Heart link ECMO Center, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Groby Road, Leicester, United Kingdom
ASAIO J 51:281-7. 2005..Using a single PMP oxygenator in the first instance may be adequate for the majority of patients and would significantly reduce red blood cell consumption during ECMO...
- Fatal thrombosis with activated factor VII in a paediatric patient on extracorporeal membrane oxygenationRichard P Chalwin
Department of ECMO, Glenfield Hospital, Leicester, LE3 9QP, UK
Eur J Cardiothorac Surg 34:685-6. 2008..Its use is generally found to be safe. We report a paediatric patient who developed fatal thrombosis with the use of rFVIIa whilst on extracorporeal membrane oxygenation and discuss the possible factors that lead to fatal thrombosis...
- Extracorporeal membrane oxygenation and severe acute respiratory distress secondary to legionella: 10 year experienceMoronke A Noah
From the Heartlink ECMO Centre, University Hospitals of Leicester NHS Trust, Leicester, UK
ASAIO J 59:328-30. 2013..Sixteen patients (84%) survived to hospital discharge. Extracorporeal membrane oxygenation should be considered in patients with Legionella-associated respiratory failure, who have failed conventional ventilation...
- Efficacy of prone ventilation in adult patients with acute respiratory failure: a meta-analysisRavindranath Tiruvoipati
Department of ECMO, Glenfield Hospital, Leicester, LE3 9QP, UK
J Crit Care 23:101-10. 2008..The use of prone ventilation in acute respiratory failure has been investigated by several randomized controlled trials in the recent past. To date, there has been no systematic review or meta-analysis of these trials...
- Venovenous extracorporeal membrane oxygenation for respiratory failure in inotrope dependent neonatesNeil Roberts
Heartlink ECMO Centre, Glenfield Hospital, Groby Road, Leicester LE3 9QQ, United Kingdom
ASAIO J 49:568-71. 2003..e., mean blood pressure < 35 mm Hg despite inotrope score of > 100)...
- Partial liquid ventilationMark C K Hamilton
Department of Radiology, Glenfield Hospital, Groby Road, Leicester, LE3 9QP, UK
Pediatr Radiol 35:1152-6. 2005....
- Improving the quality of reporting randomized controlled trials in cardiothoracic surgery: the way forwardRavindranath Tiruvoipati
Department of Cardiac Surgery and ECMO, Glenfield Hospital, Leicester, Leicester, United Kingdom
J Thorac Cardiovasc Surg 132:233-40. 2006....
- Pump Controlled Retrograde Trial Off from VA-ECMOClaire Westrope
From the Heartlink ECMO Centre, Glenfield Hospital, Leicester, United Kingdom
ASAIO J 59:517-9. 2013..This technique avoids the insertion of an arteriovenous bridge and the need to clamp the circuit. We present data on five neonatal patients who were trialled off using this method. ..
- Congenital atresia of the ostium of left main coronary artery: a rare coronary anomaly, diagnostic difficulty and successful surgical revascularizationPhilip Varghese
University Hospital of Leicester NHS Trust, Department of Cardiothoracic Surgery, Leicester, UK
Congenit Heart Dis 2:347-50. 2007..A definitive diagnosis of atresia of the left coronary ostium was only established intraoperatively. Patient underwent successful surgical angioplasty with an autologous pericardial patch...
- Early experience with a polymethyl pentene oxygenator for adult extracorporeal life supportGiles J Peek
Division of Cardiac Surgery, University of Leicester, Glenfield Hospital, University Hospitals of Leicester NHS Trust, UK
ASAIO J 48:480-2. 2002..Mean duration of ECLS was 151.7 hours (+/-75.6). Our initial experience with PMP oxygenators in adults was satisfactory, and platelet consumption and resistance to blood flow seem to be greatly reduced with PMP...
- Predictors of outcome in patients with congenital diaphragmatic hernia requiring extracorporeal membrane oxygenationRavindranath Tiruvoipati
Department of ECMO, Glenfield Hospital, LE3 9QP Leicester, United Kingdom
J Pediatr Surg 42:1345-50. 2007..There are no reliable predictors of outcome in patients requiring ECMO. We aimed to identify (a) the factors that could predict outcome and (b) the incidence and relation of complications during ECMO to outcome...
- The use of transesophageal echocardiography to demonstrate obstruction of venous drainage cannula during ECMOAaron M Ranasinghe
Heartlink ECMO Centre, Division of Cardiac Surgery, University of Leicester, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester UK
ASAIO J 50:619-20. 2004
- Plasma concentrations of midazolam in neonates receiving extracorporeal membrane oxygenationHussain Mulla
University Hospitals of Leicester De Montfort University, England
ASAIO J 49:41-7. 2003..Subsequently, and because of circuit saturation, maintenance doses should be reduced...
- Deaths from Chickenpox. Extracorporeal membrane oxygenation has important roleNeil Roberts
BMJ 324:610-1. 2002