Genomes and Genes
Laura R Pearce
Affiliation: University of Dundee
- Pearce L, Huang X, Boudeau J, Pawłowski R, Wullschleger S, Deak M, et al. Identification of Protor as a novel Rictor-binding component of mTOR complex-2. Biochem J. 2007;405:513-22 pubmed..Protor-1 is a novel Rictor-binding subunit of mTORC2, but further work is required to establish its role. ..
- Pearce L, Komander D, Alessi D. The nuts and bolts of AGC protein kinases. Nat Rev Mol Cell Biol. 2010;11:9-22 pubmed publisher..In addition, AGC kinases mediate diverse and important cellular functions, and their mutation and/or dysregulation contributes to the pathogenesis of many human diseases, including cancer and diabetes. ..