Stephen Payne

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi request reprint The response of the cross-bridge cycle model to oscillations in intracellular calcium: A mathematical analysis
    Stephen Payne
    Department of Engineering Science, University of Oxford, Parks Road, Oxford OX1 3PJ, UK phone 44 1865 283306 fax 44 1865 273905 e mail
    Conf Proc IEEE Eng Med Biol Soc 7:7305-8. 2005
  2. pmc Effects of autoregulation and CO2 reactivity on cerebral oxygen transport
    S J Payne
    Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK
    Ann Biomed Eng 37:2288-98. 2009
  3. ncbi request reprint The estimation of cerebral metabolic rate of O2 from Near Infra-Red Spectroscopy
    Stephen Payne
    Department of Engineering Science, University of Oxford, Parks Road, Oxford OX1 3PJ, UK phone 44 1865 283306 fax 44 1865 273905 e mail
    Conf Proc IEEE Eng Med Biol Soc 4:3974-7. 2005
  4. ncbi request reprint Automated classification and analysis of the calcium response of single T lymphocytes using a neural network approach
    S J Payne
    Department of Engineering Science, University of Oxford, Oxford OX1 3PJ, UK
    IEEE Trans Neural Netw 16:949-58. 2005
  5. ncbi request reprint Analysis of the effects of gravity and wall thickness in a model of blood flow through axisymmetric vessels
    S J Payne
    Department of Engineering Science, University of Oxford, Oxford, UK
    Med Biol Eng Comput 42:799-806. 2004
  6. ncbi request reprint Combined transfer function analysis and modelling of cerebral autoregulation
    S J Payne
    Department of Engineering Science, University of Oxford, Parks Road, OX1 3PJ, Oxford, UK
    Ann Biomed Eng 34:847-58. 2006
  7. doi request reprint Mathematical study of the effects of different intrahepatic cooling on thermal ablation zones
    Tingying Peng
    Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, UK
    Conf Proc IEEE Eng Med Biol Soc 2011:6866-9. 2011
  8. ncbi request reprint Mathematical modeling of thermal ablation
    S J Payne
    Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK
    Crit Rev Biomed Eng 38:21-30. 2010
  9. doi request reprint Modelling the effects of cardiac pulsations in arterial spin labelling
    S M Kazan
    Department of Engineering Science, University of Oxford, Parks Road, Oxford OX1 3PJ, UK
    Phys Med Biol 55:799-816. 2010
  10. doi request reprint Computerised electronic foetal heart rate monitoring in labour: automated contraction identification
    A Georgieva
    Nuffield Department of Obstetrics and Gynaecology, University of Oxford, The John Radcliffe Hospital, Oxford, UK
    Med Biol Eng Comput 47:1315-20. 2009

Detail Information

Publications22

  1. ncbi request reprint The response of the cross-bridge cycle model to oscillations in intracellular calcium: A mathematical analysis
    Stephen Payne
    Department of Engineering Science, University of Oxford, Parks Road, Oxford OX1 3PJ, UK phone 44 1865 283306 fax 44 1865 273905 e mail
    Conf Proc IEEE Eng Med Biol Soc 7:7305-8. 2005
    ..e. the response is purely passive...
  2. pmc Effects of autoregulation and CO2 reactivity on cerebral oxygen transport
    S J Payne
    Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK
    Ann Biomed Eng 37:2288-98. 2009
    ..The question of whether dynamic cerebral autoregulation is affected under conditions of stenosis or stroke is then examined...
  3. ncbi request reprint The estimation of cerebral metabolic rate of O2 from Near Infra-Red Spectroscopy
    Stephen Payne
    Department of Engineering Science, University of Oxford, Parks Road, Oxford OX1 3PJ, UK phone 44 1865 283306 fax 44 1865 273905 e mail
    Conf Proc IEEE Eng Med Biol Soc 4:3974-7. 2005
    ..Initial simulations under dynamic conditions seem to support the hypothesis that dynamic changes in CMRO2 can also be estimated accurately, although this is still work in progress...
  4. ncbi request reprint Automated classification and analysis of the calcium response of single T lymphocytes using a neural network approach
    S J Payne
    Department of Engineering Science, University of Oxford, Oxford OX1 3PJ, UK
    IEEE Trans Neural Netw 16:949-58. 2005
    ..Future refinement of the algorithm may allow the identification of more classes, which may be important in different immune responses associated with disease...
  5. ncbi request reprint Analysis of the effects of gravity and wall thickness in a model of blood flow through axisymmetric vessels
    S J Payne
    Department of Engineering Science, University of Oxford, Oxford, UK
    Med Biol Eng Comput 42:799-806. 2004
    ..Gravity and wall thickness thus have a significant impact on a number of aspects of the fluid and wall behaviour, despite conventionally being neglected...
  6. ncbi request reprint Combined transfer function analysis and modelling of cerebral autoregulation
    S J Payne
    Department of Engineering Science, University of Oxford, Parks Road, OX1 3PJ, Oxford, UK
    Ann Biomed Eng 34:847-58. 2006
    ..A transfer function approach can be used to estimate autoregulation status clinically using a physiologically-based model, thus providing greater insight into the processes that govern cerebral autoregulation...
  7. doi request reprint Mathematical study of the effects of different intrahepatic cooling on thermal ablation zones
    Tingying Peng
    Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, UK
    Conf Proc IEEE Eng Med Biol Soc 2011:6866-9. 2011
    ..In contrast, different amount of surface heat convection on the vessel wall between these two types of veins, however, has a minor effect...
  8. ncbi request reprint Mathematical modeling of thermal ablation
    S J Payne
    Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK
    Crit Rev Biomed Eng 38:21-30. 2010
    ..The primary intentions are to provide a critical scientific review and a practical guide for researchers wishing to use such models in clinical applications...
  9. doi request reprint Modelling the effects of cardiac pulsations in arterial spin labelling
    S M Kazan
    Department of Engineering Science, University of Oxford, Parks Road, Oxford OX1 3PJ, UK
    Phys Med Biol 55:799-816. 2010
    ..However, cardiac pulsatility only appears to have a small effect on the quantification of perfusion estimates...
  10. doi request reprint Computerised electronic foetal heart rate monitoring in labour: automated contraction identification
    A Georgieva
    Nuffield Department of Obstetrics and Gynaecology, University of Oxford, The John Radcliffe Hospital, Oxford, UK
    Med Biol Eng Comput 47:1315-20. 2009
    ..It was concluded that the proposed method can be employed with confidence in our study on foetal health assessment in labour and future OxSys development...
  11. ncbi request reprint Synchronization between arterial blood pressure and cerebral oxyhaemoglobin concentration investigated by wavelet cross-correlation
    A B Rowley
    Department of Engineering Science, University of Oxford, Oxford, UK
    Physiol Meas 28:161-73. 2007
    ....
  12. ncbi request reprint A model of the interaction between autoregulation and neural activation in the brain
    S J Payne
    Department of Engineering Science, University of Oxford, Parks Road, Oxford OX1 3PJ, UK
    Math Biosci 204:260-81. 2006
    ..Dynamic changes in ABP also have a significant and potentially confounding impact on the measured deoxyhaemoglobin response to neural activation...
  13. ncbi request reprint A physiological model of the interaction between tissue bubbles and the formation of blood-borne bubbles under decompression
    M A Chappell
    Department of Engineering Science, University of Oxford, Parks Road, Oxford OX1 3PJ, UK
    Phys Med Biol 51:2321-38. 2006
    ..However, the density of nucleation sites in the blood is unlikely to be sufficiently high in humans for the formation of bubbles in the blood to have a significant impact on the growth of the bubbles in the tissue...
  14. ncbi request reprint A physiological model of the release of gas bubbles from crevices under decompression
    M A Chappell
    Department of Engineering Science, University of Oxford, Parks Road, Oxford OX1 3PJ, UK
    Respir Physiol Neurobiol 153:166-80. 2006
    ..It was found that the presence of metabolic gases has a significant effect on the behavior under decompression and that this appears to be due to the high diffusivity of these gases...
  15. ncbi request reprint A method for the automated detection of venous gas bubbles in humans using empirical mode decomposition
    M A Chappell
    Department of Engineering Science, University of Oxford, Parks Road, Oxford OX1 3PJ, UK
    Ann Biomed Eng 33:1411-21. 2005
    ..This method has been applied to a subset of the available database and appears to perform with good sensitivity even when the signal has variable signal strength...
  16. ncbi request reprint A physiological model of gas pockets in crevices and their behavior under compression
    M A Chappell
    Department of Engineering Science, University of Oxford, Parks Road, Oxford OX1 3PJ, UK
    Respir Physiol Neurobiol 152:100-14. 2006
    ....
  17. doi request reprint The influence of network structure on the transport of blood in the human cerebral microvasculature
    Shen Wei Su
    Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK
    Microcirculation 19:175-87. 2012
    ..This could have a significant impact on improving clinical outcomes for vascular brain diseases, particularly vascular dementia, where localized flow patterns are very important...
  18. doi request reprint Quantification of the effects of vasomotion on mass transport to tissue from axisymmetric blood vessels
    Tharindi Hapuarachchi
    Department of Engineering Science, Institute of Biomedical Engineering, University of Oxford, Parks Road, Oxford OX1 3PJ, UK
    J Theor Biol 264:553-9. 2010
    ..We conclude by considering the likely implications of these results in the context of oxygen transport to tissue...
  19. doi request reprint Image-based multi-scale modelling and validation of radio-frequency ablation in liver tumours
    Stephen Payne
    Department of Engineering Science, Institute of Biomedical Engineering, University of Oxford, Oxford OX1 3PJ, UK
    Philos Transact A Math Phys Eng Sci 369:4233-54. 2011
    ..This is the first time that such a 'loop' of mathematical modelling and experimental validation in vivo has been performed in this context, and such validation enables us to make quantitative estimates of error...
  20. pmc Modelling of pH dynamics in brain cells after stroke
    Piotr Orlowski
    Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford, Oxford, UK
    Interface Focus 1:408-16. 2011
    ....
  21. doi request reprint A two-equation coupled system model for determination of liver tissue temperature during radio frequency ablation
    D P O'Neill
    Department of Engineering Science, University of Oxford, UK
    Conf Proc IEEE Eng Med Biol Soc 2009:3893-6. 2009
    ....
  22. ncbi request reprint Pyridoxalphosphate-6-azophenyl-2',4'-disulphonic acid (PPADS) as a tool for differentiation of P2Y2-receptor-mediated vasorelaxation in guinea pig aorta
    S J Payne
    Liver Sciences Unit, Academic Department of Surgery, GKT School of Medicine, St Thomas Hospital, London
    Methods Find Exp Clin Pharmacol 24:351-6. 2002
    ..Thus, PPADS is a potentially useful substance that may be used for differentiation between P2Y1 and P2Y2 receptors in the guinea pig aorta...