Elspeth M Payne

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi Ddx18 is essential for cell-cycle progression in zebrafish hematopoietic cells and is mutated in human AML
    Elspeth M Payne
    Department of Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA
    Blood 118:903-15. 2011
  2. ncbi cpsf1 is required for definitive HSC survival in zebrafish
    Niccolò Bolli
    Department of Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA
    Blood 117:3996-4007. 2011
  3. ncbi Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of hematopoietic cells in zebrafish
    Niccolò Bolli
    Department of Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA
    Blood 115:3329-40. 2010
  4. ncbi L-Leucine improves the anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q) MDS by activating the mTOR pathway
    Elspeth M Payne
    Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA
    Blood 120:2214-24. 2012

Detail Information

Publications4

  1. ncbi Ddx18 is essential for cell-cycle progression in zebrafish hematopoietic cells and is mutated in human AML
    Elspeth M Payne
    Department of Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA
    Blood 118:903-15. 2011
    ....
  2. ncbi cpsf1 is required for definitive HSC survival in zebrafish
    Niccolò Bolli
    Department of Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA
    Blood 117:3996-4007. 2011
    ..These studies show that cpsf1 is essential for HSC survival and differentiation in caudal hematopoietic tissue...
  3. ncbi Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of hematopoietic cells in zebrafish
    Niccolò Bolli
    Department of Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA
    Blood 115:3329-40. 2010
    ..These results are likely to be relevant to human NPMc+ AML, where the observed NPMc+ multilineage expression pattern implies transformation of a multipotent stem or progenitor cell...
  4. ncbi L-Leucine improves the anemia and developmental defects associated with Diamond-Blackfan anemia and del(5q) MDS by activating the mTOR pathway
    Elspeth M Payne
    Pediatric Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA, USA
    Blood 120:2214-24. 2012
    ..Our studies support the rationale for ongoing clinical trials of L-leucine as a therapeutic agent for DBA, and potentially for patients with del(5q) MDS...