Research Topics
| Eugene S PaykelSummaryAffiliation: University of Cambridge Country: UK Publications
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Detail Information
Publications
Cohort differences in disease and disability in the young-old: findings from the MRC Cognitive Function and Ageing Study (MRC-CFAS)Carol Jagger
Leicester Nuffield Research Unit, Department of Health Sciences, University of Leicester, UK
BMC Public Health 7:156. 2007..We use a repeated population-based cross-sectional study from the Cambridgeshire centre of the UK Medical Research Council Cognitive Function and Ageing Study to investigate trends in the health of the young-old UK population..
Partial remission, residual symptoms, and relapse in depressionE S Paykel
University of Cambridge, Department of Psychiatry, Cambridge, UK
Dialogues Clin Neurosci 10:431-7. 2008..Residual symptoms are a strong indication for vigorous and longer than usual continuation of antidepressant treatment in order to prevent relapse. There is good evidence for the use of cognitive therapy as an adjunct...
Do treated psychiatric patients become later community cases? A prospective cohort studyE S Paykel
Dept of Psychiatry, Cambridge, University of Cambridge, UK
Eur Psychiatry 21:315-8. 2006....
Mood disorders: review of current diagnostic systemsEugene S Paykel
Department of Psychiatry, University of Cambridge, Cambridge, UK
Psychopathology 35:94-9. 2002....
Duration of relapse prevention after cognitive therapy in residual depression: follow-up of controlled trialE S Paykel
Department of Psychiatry, University of Cambridge, UK
Psychol Med 35:59-68. 2005..Although there is good evidence that cognitive therapy (CBT) lessens relapse and recurrence in unipolar depression, the duration of this effect is not known...
Cognitive therapy in relapse prevention in depressionEugene S Paykel
Department of Psychiatry, University of Cambridge, Cambridge, UK
Int J Neuropsychopharmacol 10:131-6. 2007..Incorporation into routine clinical practice is now appropriate and recommendations are proposed...
Sub-syndromal and syndromal symptoms in the longitudinal course of bipolar disorderEugene S Paykel
Department of Psychiatry, University of Cambridge, Douglas House, 18E Trumpington Road, Cambridge CB2 2AH, UK
Br J Psychiatry 189:118-23. 2006..There have been few detailed longitudinal symptom studies of bipolar disorder...
Basic concepts of depressionEugene S Paykel
University of Cambridge, Department of Psychiatry, Cambridge, UK
Dialogues Clin Neurosci 10:279-89. 2008..Life stress is common in various depressive pictures. Dysthymia, a valuable diagnosis, represents a form of what was regarded earlier as neurotic depression. Other subtypes are also discussed...
Remission and recurrence of depression in the maintenance era: long-term outcome in a Cambridge cohortN Kennedy
Department of Psychiatry, University of Cambridge, Addenbrooke's Hospital
Psychol Med 33:827-38. 2003..CONCLUSIONS: The long-term outcome of depression still shows high recurrence rates and does not appear to have changed in the last 20 years...
Size and burden of depressive disorders in EuropeEugene S Paykel
University of Cambridge, Department of Psychiatry, Douglas House, 18E Trumpington Road, Cambridge CB2 2AH, UK
Eur Neuropsychopharmacol 15:411-23. 2005..There is a need for public health programmes aimed at improving treatment, reducing rates and consequences of depressive disorders...
How does cognitive therapy prevent relapse in residual depression? Evidence from a controlled trialJ D Teasdale
Cognition and Brain Sciences Unit, Medical Research Council, Cambridge, United Kingdom
J Consult Clin Psychol 69:347-57. 2001..CT may prevent relapse by training patients to change the way that they process depression-related material rather than by changing belief in depressive thought content...
Long-term outcome of offspring after maternal severe puerperal disorderR Abbott
Department of Psychiatry, University of Cambridge, Cambridge CB2 2QQ, UK
Acta Psychiatr Scand 110:365-73. 2004..To study adult mental health in offspring of mothers who experienced severe puerperal disorder...
Decline across different domains of cognitive function in normal ageing: results of a longitudinal population-based study using CAMCOGS Cullum
Department of Community Medicine, University of Cambridge, UK
Int J Geriatr Psychiatry 15:853-62. 2000..05). Greater decline in the Perception subscale was associated with older age (p = 0.03). Decline in specific cognitive domains may indicate a reversible phase of cognitive impairment and deserves further investigation...
Continuation and maintenance therapy in depressionE S Paykel
Department of Psychiatry, University of Cambridge, UK
Br Med Bull 57:145-59. 2001..There is better evidence for effects of cognitive therapy in preventing relapse and an emerging indication for its addition to antidepressants, particularly where residual symptoms are present...
Treatment and response in refractory depression: results from a specialist affective disorders serviceN Kennedy
Department of Psychiatry, University of Cambridge, UK
J Affect Disord 81:49-53. 2004..This study aimed to identify short-term outcome and most successful somatic treatments of severe refractory depressives referred to an affective disorders service...
Decision-making cognition in mania and depressionF C Murphy
Department of Psychiatry, University of Cambridge
Psychol Med 31:679-93. 2001..Viewed in the context of other recent studies, these findings are consistent with a role for the ventromedial prefrontal cortex in mediating mood-cognition relationships...
Residual symptoms at remission from depression: impact on long-term outcomeN Kennedy
Department of Psychiatry, University of Cambridge, Cambridge, UK
J Affect Disord 80:135-44. 2004..Although residual symptoms after remission from depression are common and predict early relapse, little is known about the impact of residual symptoms on longer-term clinical course of depression or social functioning...
Population norms for the MMSE in the very old: estimates based on longitudinal data. Mini-Mental State ExaminationC Dufouil
MRC Biostatistics Unit, Institute of Public Health, Cambridge, UK
Neurology 55:1609-13. 2000..To report the percentile distribution of Mini-Mental State Examination (MMSE) scores in older people by age, sex, and education level, estimated from longitudinal data, after correcting for loss due to dropout...
No association of an insertion/deletion polymorphism in the angiotensin I converting enzyme gene with bipolar or unipolar affective disordersR A Furlong
Department of Medical Genetics, University of Cambridge, Wellcome Trust Centre for the Study of Molecular Mechanisms in Disease, Cambridge Institute for Medical Research, Addenbrooke s Hospital, Cambridge, United Kingdom
Am J Med Genet 96:733-5. 2000..These results do not support the ACE gene having a major role in the etiology of either bipolar or unipolar affective disorders. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 96:733-735, 2000...
Stress and affective disorders in humansE S Paykel
Department of Psychiatry, University of Cambridge, Cambridge, UK
Semin Clin Neuropsychiatry 6:4-11. 2001....
3H-imipramine binding to previously frozen platelet membranes from depressed patients, before and after treatmentD Healy
Department of Psychiatry, University of Cambridge
Br J Psychiatry 157:208-15. 1990....
Decision-making in mania: a PET studyJ S Rubinsztein
Department of Psychiatry, University of Cambridge, Cambridge, UK
Brain 124:2550-63. 2001....
Longitudinal syndromal and sub-syndromal symptoms after severe depression: 10-year follow-up studyNoel Kennedy
Institute of Psychiatry, London, UK
Br J Psychiatry 184:330-6. 2004..Few follow-up studies of depression have evaluated depressive symptomatology over time at both threshold and sub-threshold levels...
Depression: major problem for public healthEugene S Paykel
Epidemiol Psichiatr Soc 15:4-10. 2006..There is a need for public health programmes aimed at improving recognition, treatment, and reducing consequences...
Advances in the treatment of affective disordersPeter R Joyce
Aust N Z J Psychiatry 40:379-80. 2006
Do SSRIs or antidepressants in general increase suicidality? WPA Section on Pharmacopsychiatry: consensus statementHans Jurgen Moller
Department of Psychiatry, Ludwig Maximilians University Munchen, Nussbaumstrasse 7, 80336 Munich, Germany
Eur Arch Psychiatry Clin Neurosci 258:3-23. 2008..It is the major problem facing efforts to identify the possible 'suicidal effects' of antidepressants...
