Dominic C Paviour

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi Can the frontal assessment battery (FAB) differentiate bradykinetic rigid syndromes? Relation of the FAB to formal neuropsychological testing
    D C Paviour
    The Sara Koe PSP Research Centre, Institute of Neurology, London, UK
    Neurocase 11:274-82. 2005
  2. ncbi MRI derived brain atrophy in PSP and MSA-P. Determining sample size to detect treatment effects
    Dominic C Paviour
    The Sara Koe PSP Research Centre, Institute of Neurology, 1 Wakefield Street, London WC1N, UK
    J Neurol 254:478-81. 2007
  3. ncbi Diffusion-weighted magnetic resonance imaging differentiates Parkinsonian variant of multiple-system atrophy from progressive supranuclear palsy
    Dominic C Paviour
    Sara Koe PSP Research Centre, Institute of Neurology, University College London, London, United Kingdom
    Mov Disord 22:68-74. 2007
  4. ncbi Holmes tremor: Application of modern neuroimaging techniques
    Dominic C Paviour
    The Sara Koe PSP Research Centre, The Institute of Neurology, UCL, London, United Kingdom
    Mov Disord 21:2260-2. 2006
  5. pmc Pathological substrate for regional distribution of increased atrophy rates in progressive supranuclear palsy
    D C Paviour
    The Sara Koe PSP Research Centre, Institute of Neurology UCL, London, UK
    J Neurol Neurosurg Psychiatry 75:1772-5. 2004
  6. ncbi Quantitative MRI measurement of superior cerebellar peduncle in progressive supranuclear palsy
    D C Paviour
    Dementia Research Centre UCL, Institute of Neurology UCL, London, UK
    Neurology 64:675-9. 2005
  7. ncbi Regional brain volumes distinguish PSP, MSA-P, and PD: MRI-based clinico-radiological correlations
    Dominic C Paviour
    The Sara Koe PSP Research Centre, Institute of Neurology UCL, London United Kingdom
    Mov Disord 21:989-96. 2006
  8. ncbi Longitudinal MRI in progressive supranuclear palsy and multiple system atrophy: rates and regions of atrophy
    Dominic C Paviour
    The Sara Koe PSP Research Centre, Institute of Neurology, UCL, London UK
    Brain 129:1040-9. 2006
  9. doi The midbrain to pons ratio: a simple and specific MRI sign of progressive supranuclear palsy
    Luke A Massey
    Sara Koe PSP Research Centre, Rita Lila Weston Institute for Neurology Studies and Queen Square Brain Bank, Department of Molecular Neurosciences, UCL Institute of Neurology, London, UK
    Neurology 80:1856-61. 2013
  10. doi Conventional magnetic resonance imaging in confirmed progressive supranuclear palsy and multiple system atrophy
    Luke A Massey
    Sara Koe PSP Research Centre, UCL Institute of Neurology, University College London, London, United Kingdom
    Mov Disord 27:1754-62. 2012

Detail Information

Publications18

  1. ncbi Can the frontal assessment battery (FAB) differentiate bradykinetic rigid syndromes? Relation of the FAB to formal neuropsychological testing
    D C Paviour
    The Sara Koe PSP Research Centre, Institute of Neurology, London, UK
    Neurocase 11:274-82. 2005
    ..These results suggest that the FAB is a valid and easily applicable bedside test to discriminate executive dysfunction in these three frequently confused bradykinetic rigid syndromes...
  2. ncbi MRI derived brain atrophy in PSP and MSA-P. Determining sample size to detect treatment effects
    Dominic C Paviour
    The Sara Koe PSP Research Centre, Institute of Neurology, 1 Wakefield Street, London WC1N, UK
    J Neurol 254:478-81. 2007
    ..Regional rather than whole brain atrophy rates calculated from volumetric serial MRI brain scans in PSP and MSA-P provide a more practical and powerful means of monitoring disease progression in clinical trials...
  3. ncbi Diffusion-weighted magnetic resonance imaging differentiates Parkinsonian variant of multiple-system atrophy from progressive supranuclear palsy
    Dominic C Paviour
    Sara Koe PSP Research Centre, Institute of Neurology, University College London, London, United Kingdom
    Mov Disord 22:68-74. 2007
    ..Increased rADCs in the pons and MCP were associated with smaller pontine and cerebellar volumes in MSA-P. rADCs distinguish MSA-P from PSP. These have a clinical correlate and are associated with reduced brainstem and cerebellar volumes...
  4. ncbi Holmes tremor: Application of modern neuroimaging techniques
    Dominic C Paviour
    The Sara Koe PSP Research Centre, The Institute of Neurology, UCL, London, United Kingdom
    Mov Disord 21:2260-2. 2006
    ..Modern neuroimaging techniques in this case confirm that a combination of damage to the cerebello-rubrothalamic pathway and the nigrostriatal pathway is required for the full Holmes tremor syndrome to occur...
  5. pmc Pathological substrate for regional distribution of increased atrophy rates in progressive supranuclear palsy
    D C Paviour
    The Sara Koe PSP Research Centre, Institute of Neurology UCL, London, UK
    J Neurol Neurosurg Psychiatry 75:1772-5. 2004
    ..MRI features described previously in PSP correspond to regions of pathological involvement demonstrated in separate studies, but serial MRI with pathological follow up has not been undertaken...
  6. ncbi Quantitative MRI measurement of superior cerebellar peduncle in progressive supranuclear palsy
    D C Paviour
    Dementia Research Centre UCL, Institute of Neurology UCL, London, UK
    Neurology 64:675-9. 2005
    ..It is not clear whether MRI-based measurements can differentiate this relative atrophy of the SCP during life...
  7. ncbi Regional brain volumes distinguish PSP, MSA-P, and PD: MRI-based clinico-radiological correlations
    Dominic C Paviour
    The Sara Koe PSP Research Centre, Institute of Neurology UCL, London United Kingdom
    Mov Disord 21:989-96. 2006
    ..These distinct patterns of cortical and subcortical atrophy, when considered together rather than independently, better differentiate PSP and MSA-P from each other and also from healthy controls...
  8. ncbi Longitudinal MRI in progressive supranuclear palsy and multiple system atrophy: rates and regions of atrophy
    Dominic C Paviour
    The Sara Koe PSP Research Centre, Institute of Neurology, UCL, London UK
    Brain 129:1040-9. 2006
    ..Clinico-radiological associations suggest these regional atrophy rates have potential as markers of disease progression in trials of novel therapies...
  9. doi The midbrain to pons ratio: a simple and specific MRI sign of progressive supranuclear palsy
    Luke A Massey
    Sara Koe PSP Research Centre, Rita Lila Weston Institute for Neurology Studies and Queen Square Brain Bank, Department of Molecular Neurosciences, UCL Institute of Neurology, London, UK
    Neurology 80:1856-61. 2013
    ..We aimed to develop in histologically proven disease a simple measure of the midbrain and pons on sagittal MRI to identify PSP...
  10. doi Conventional magnetic resonance imaging in confirmed progressive supranuclear palsy and multiple system atrophy
    Luke A Massey
    Sara Koe PSP Research Centre, UCL Institute of Neurology, University College London, London, United Kingdom
    Mov Disord 27:1754-62. 2012
    ..However, the low sensitivity of these and macroscopic findings at autopsy suggest a need for imaging techniques sensitive to microstructural abnormalities without regional atrophy...
  11. doi Does corticobasal degeneration exist? A clinicopathological re-evaluation
    Helen Ling
    Reta Lila Weston Institute of Neurological Studies, Institute of Neurology, University College London, 1 Wakefield Street, London WC1N 1PJ, UK
    Brain 133:2045-57. 2010
    ..Despite these diagnostic difficulties we conclude that corticobasal degeneration is a discrete clinicopathological entity but with a broader clinical spectrum than was originally proposed...
  12. ncbi Neuronal intranuclear inclusion disease: report on a case originally diagnosed as dopa-responsive dystonia with Lewy bodies
    Dominic C Paviour
    The Sara Koe Progressive Supranuclear Palsy Research Centre, Institute of Neurology, University College London, London, United Kingdom
    Mov Disord 20:1345-9. 2005
    ..This rare condition, which may be diagnosed in life with a full thickness rectal biopsy, needs to be considered in the differential diagnosis of any case presenting as progressive juvenile parkinsonism (JP) or dystonia...
  13. ncbi Delineating the sites and progression of in vivo atrophy in multiple system atrophy using fluid-registered MRI
    Jonathan M Schott
    Dementia Research Group, Institute of Neurology, London, United Kingdom
    Mov Disord 18:955-8. 2003
    ..The in vivo findings were consistent with those found at postmortem, including significant supratentorial atrophy concurrent with an unusual degree of cognitive impairment for MSA...
  14. ncbi Diagnostic considerations in juvenile parkinsonism
    Dominic C Paviour
    National Hospital for Neurology and Neurosurgery, Queen Square, London, United Kingdom
    Mov Disord 19:123-35. 2004
    ..Lewy body pathology has only been reported in one case, suggesting that a juvenile form of idiopathic Parkinson's disease may be extremely rare...
  15. ncbi Characteristics of two distinct clinical phenotypes in pathologically proven progressive supranuclear palsy: Richardson's syndrome and PSP-parkinsonism
    David R Williams
    The Queen Square Brain Bank for Neurological Disorders, University College London, UK
    Brain 128:1247-58. 2005
    ..The different tau isoform deposition in the basal pons suggests that this may ultimately prove to be a discrete nosological entity...
  16. ncbi Is sphincter electromyography a helpful investigation in the diagnosis of multiple system atrophy? A retrospective study with pathological diagnosis
    Dominic C Paviour
    The Sara Koe PSP Research Centre, Institute of Neurology, London, United Kingdom
    Mov Disord 20:1425-30. 2005
    ..A normal spEMG is unlikely in pathologically proven MSA, at least in cases with a mean symptom duration of more than 5 years when the test is performed...
  17. ncbi Frontotemporal lobar degeneration with ubiquitin-only-immunoreactive neuronal changes: broadening the clinical picture to include progressive supranuclear palsy
    D C Paviour
    The Sara Koe PSP Research Centre, Institute of Neurology, London, UK
    Brain 127:2441-51. 2004
    ..FTLD-U or FTLD-MND should be considered in the differential diagnosis of progressive frontal dementia with an akinetic rigid syndrome and supranuclear gaze palsy or Steele-Richardson-Olszewski disease...
  18. ncbi Rapidly progressive behavioral changes and parkinsonism in a 68-year-old man
    Galit Kleiner-Fisman
    Department of Medicine, Division of Neurology, Toronto Western Hospital, Toronto, Ontario, Canada
    Mov Disord 19:534-43. 2004