H A Patsos
Affiliation: University of Bristol
- Prospects in NSAID-derived chemoprevention of colorectal cancerS Chell
Cancer Research UK, Colorectal Tumour Biology Group, Department of Pathology and Microbiology, Bristol University, Bristol BS8 1TD, UK
Biochem Soc Trans 33:667-71. 2005..Selective (and possibly combinatorial) inhibition of the synthesis and signalling of those PGs most highly associated with colorectal tumorigenesis may have some advantages over COX-2-selective inhibitors...
- Cannabinoids and cancer: potential for colorectal cancer therapyH A Patsos
Cancer Research UK Colorectal Tumour Biology Group, Department of Cellular and Molecular Medicine, School of Medical Sciences, University of Bristol, Bristol BS8 1TD, UK
Biochem Soc Trans 33:712-4. 2005..The chemotherapeutic potential for plant-derived and endogenous cannabinoids in CRC therapy is reviewed...
- The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2H A Patsos
Cancer Research UK Colorectal Tumour Biology Group, Department of Pathology and Microbiology, School of Medical Sciences, University Walk, University of Bristol, Bristol BS8 1TD, UK
Gut 54:1741-50. 2005....
- The retinoblastoma protein (Rb) as an anti-apoptotic factor: expression of Rb is required for the anti-apoptotic function of BAG-1 protein in colorectal tumour cellsT J Collard
Cancer Research UK Colorectal Tumour Biology Research Group, School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK
Cell Death Dis 3:e408. 2012..As BAG-1 is highly expressed in the majority of colorectal tumours, targeting the Rb-BAG-1 complex to promote apoptosis has exciting potential for future therapeutic development...