Research Topics
| A C ParrottSummaryAffiliation: University of East London Country: UK Publications
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Detail Information
Publications
Cognitive performance in recreational users of MDMA of 'ecstasy': evidence for memory deficitsA C Parrott
Department of Psychology, University of East London, UK
J Psychopharmacol 12:79-83. 1998..Although the design of this study was far from ideal, these data are consistent with other findings of memory decrements in recreational MDMA users, possibly caused by serotonergic neurotoxicity...
Nesbitt's Paradox resolved? Stress and arousal modulation during cigarette smokingA C Parrott
Department of Psychology, University of East London, UK
Addiction 93:27-39. 1998..Nesbitt's Paradox is therefore not actually a paradox; it never was a paradox...
Ecstasy (MDMA) effects upon mood and cognition: before, during and after a Saturday night danceA C Parrott
Department of Psychology, University of East London, UK
Psychopharmacology (Berl) 139:261-8. 1998..The cognitive deficits in drug-free recreational ecstasy users, suggest that MDMA may also be neurotoxic in humans...
Does cigarette smoking cause stress?A C Parrott
Department of Psychology, University of East London, Great Britain
Am Psychol 54:817-20. 1999..The message that tobacco use does not alleviate stress but actually increases it needs to be far more widely known. It could help those adult smokers who wish to quit and might prevent some schoolchildren from starting...
Psychobiological problems in heavy 'ecstasy' (MDMA) polydrug usersA C Parrott
Department of Psychology, University of East London, London, UK
Drug Alcohol Depend 60:105-10. 2000..However, since repeated MDMA can cause serotonergic neurotoxicity in laboratory animals and man, these problems may reflect reduced serotonin activity induced by regular ecstasy use...
Self-rated everyday and prospective memory abilities of cigarette smokers and non-smokers: a web-based studyT M Heffernan
Human Cognitive Neuroscience Unit, Department of Psychology, Northumbria University, Newcastle upon Tyne NE1 8ST, UK
Drug Alcohol Depend 78:235-41. 2005..057). These findings suggest there are selective memory deficits associated with smoking and that long-term prospective memory deficits should be added to the growing list of problems associated with cigarette use...
Ecstasy use: cognitive deficits related to dosage rather than self-reported problematic use of the drugH C Fox
Department of Psychology, University of East London, UK
J Psychopharmacol 15:273-81. 2001..Because all Ecstasy participants also consumed a range of other illicit drugs, the results are reflective of Ecstasy polydrug use in individuals who use Ecstasy as a drug of preference...
The reality of psychomotor problems, and the possibility of Parkinson's disorder, in some recreational ecstasy/MDMA users: a rejoinder to Sumnall et al. (2003)A C Parrott
School of Psychology, University of East London, E15 4LZ, London, UK. a.c
Psychopharmacology (Berl) 171:231-3. 2004
Recreational ecstasy/MDMA and other drug users from the UK and Italy: psychiatric symptoms and psychobiological problemsA C Parrott
Department of Psychology, University of East London, London E15 4LZ, UK
Psychopharmacology (Berl) 159:77-82. 2001..Recreational drug use is increasingly widespread amongst young people, but there are concerns that psychoactive drugs may be associated with psychiatric symptoms or psychobiological problems...
Pattern of cannabis use in ecstasy polydrug users: moderate cannabis use may compensate for self-rated aggression and somatic symptomsR M Milani
Thames Valley University, London, UK
Hum Psychopharmacol 20:249-61. 2005..However, this study confirms that heavy cannabis and ecstasy use is associated with several psychobiological problems, which may emerge after a period of abstinence from both drugs...
Daily uplifts, hassles, stresses and cognitive failures: in cigarette smokers, abstaining smokers, and non-smokersA C Parrott
Department of Psychology, University of East London, UK
Behav Pharmacol 10:639-46. 1999..The repetitive use of nicotine by cigarette smokers does not seem to generate any real psychobiological gains or advantages. Instead, dependent smokers need regular hits of nicotine just to remain feeling normal...
'Is MDMA a human neurotoxin?': diverse views from the discussantsJ J Turner
Department of Psychology, University of East London, London, UK
Neuropsychobiology 42:42-8. 2000..Moreover, these deficits often remained when other illicit drug use was statistically controlled. In conclusion: If MDMA neurotoxicity in humans is a myth, then it is a myth with a heavy serotonergic component...
Problematic versus non-problematic ecstasy/MDMA use: the influence of drug usage patterns and pre-existing psychiatric factorsK Soar
School of Psychology, University of East London, Romford Road, London E15 4LZ, UK
J Psychopharmacol 20:417-24. 2006....
Persistent neuropsychological problems after 7 years of abstinence from recreational Ecstasy (MDMA): a case studyK Soar
Department of Psychology, School of Psychology, University of East London, UK
Psychol Rep 95:192-6. 2004..Severe problems with sleep and sex were also reported. Further studies involving larger groups of abstinent former users are needed; adverse sequelae associated with intensive Ecstasy use may sometimes be enduring...
Alcohol, ecstasy, Aldous Huxley's 'soma'A C Parrott
Department of Psychology, Swansea University, Swansea SA2 8PP, UK
J Psychopharmacol 21:8-9. 2007
Chronic tolerance to recreational MDMA (3,4-methylenedioxymethamphetamine) or EcstasyA C Parrott
Department of Psychology, University of Wales, Swansea, UK
J Psychopharmacol 19:71-83. 2005..Several traditional processes are probably involved, but one of the possible causes is a novel mechanism largely unique to the ring substituted amphetamine derivatives, namely serotonergic neurotoxicity...
MDMA (3,4-Methylenedioxymethamphetamine) or ecstasy: the neuropsychobiological implications of taking it at dances and ravesA C Parrott
Department of Psychology, University of Wales, Swansea, UK
Neuropsychobiology 50:329-35. 2004..Consistent with this prediction, the extent of self-reported dancing/exercise when on MDMA has recently been shown to be associated with significantly more psychobiological problems afterwards...
Ecstasy/MDMA attributed problems reported by novice, moderate and heavy recreational usersA C Parrott
Recreational Drugs Research Group, School of Psychology, University of East London, London E15 4LZ, UK
Hum Psychopharmacol 17:309-12. 2002..The recreational use of MDMA/Ecstasy (3,4-methylenedioxymethamphetamine) is associated with many psychobiological problems, but there is a paucity of data on how these relate to the level of past use...
Human research on MDMA (3,4-methylene- dioxymethamphetamine) neurotoxicity: cognitive and behavioural indices of changeA C Parrott
Department of Psychology, University of East London, London, UK
Neuropsychobiology 42:17-24. 2000..Finally, this profile of cognitive deficits is also consistent with a hypothetical integrative construct: namely reduced cortical inhibition...
Neuropsychological evidence of a relatively selective profile of temporal dysfunction in drug-free MDMA ("ecstasy") polydrug usersH C Fox
Department of Psychology, University of East London, Romford Road, London E15 4LZ, UK
Psychopharmacology (Berl) 162:203-14. 2002..The serotonin system predominantly innervates frontal and limbic regions of the brain and has been associated with consolidatory learning and mnemonic processes in humans...
The psychotherapeutic potential of MDMA (3,4-methylenedioxymethamphetamine): an evidence-based reviewA C Parrott
Department of Psychology, University of Wales Swansea, Swansea, SA2 8PP, Wales, UK
Psychopharmacology (Berl) 191:181-93. 2007..AIMS AND RATIONALE: The purpose of this study was to review whether methylenedioxymethamphetamine (MDMA) has the appropriate pharmacodynamic profile to be a therapeutic agent...
Cortisol and 3,4-methylenedioxymethamphetamine: neurohormonal aspects of bioenergetic stress in ecstasy usersA C Parrott
Department of Psychology, Swansea University, Swansea SA2 8PP, UK
Neuropsychobiology 60:148-58. 2009..3,4-Methylenedioxymethamphetamine (MDMA) can affect both neurotransmitter and neurohormonal activity. This review will debate the role of the metabolic activation hormone cortisol for the psychobiological effects of ecstasy/MDMA...
Patterns of drug use and the influence of gender on self-reports of memory ability in ecstasy users: a web-based studyJ Rodgers
Department of Clinical Psychology, University of Newcastle, Newcastle upon Tyne, UK
J Psychopharmacol 17:389-96. 2003..No gender differences were detected, suggesting that there may be a dissociation between cognitive impairment and cortical binding worthy of further exploration...
Parkinson's disorder, psychomotor problems and dopaminergic neurotoxicity in recreational ecstasy/MDMA usersA C Parrott
Psychopharmacology (Berl) 167:449-50. 2003
Ecstasy/MDMA and cannabis: the complexities of their interactive neuropsychobiological effectsA C Parrott
University of Wales, Swansea SA2 8PP, UK
J Psychopharmacol 18:572-5. 2004
Selective neurocognitive deficits associated with multiple doses of ecstasy/MDMA: a reply to ColeH C Fox
J Psychopharmacol 17:242-4. 2003
Dancing hot on Ecstasy: physical activity and thermal comfort ratings are associated with the memory and other psychobiological problems reported by recreational MDMA usersA C Parrott
University of Wales Swansea, Swansea, Wales, UK
Hum Psychopharmacol 21:285-98. 2006..We assessed whether dancing and feeling hot on Ecstasy would be associated with more psychobiological problems in recreational users...
Recreational Ecstasy/MDMA, the serotonin syndrome, and serotonergic neurotoxicityA C Parrott
Department of Psychology, University of East London, E15 4LZ, London, UK
Pharmacol Biochem Behav 71:837-44. 2002..Functional deficits may remain long after drug use has ceased and are consistent with serotonergic axonal loss in higher brain regions...
Cannabis and Ecstasy/MDMA (3,4-methylenedioxymethamphetamine): an analysis of their neuropsychobiological interactions in recreational usersA C Parrott
Swansea University, Swansea, Wales, UK
J Neural Transm 114:959-68. 2007..In order to investigate these potential complexities, future research will need better empirical data on the exact patterns of co-drug usage...
Is ecstasy MDMA? A review of the proportion of ecstasy tablets containing MDMA, their dosage levels, and the changing perceptions of purityA C Parrott
Department of Psychology, University of Wales Swansea, Swansea, SAZ 8PP, United Kingdom
Psychopharmacology (Berl) 173:234-41. 2004..The historical origins and evolution of this mismatch will be reviewed, in order to estimate the proportions of ecstasy tablets containing MDMA at different periods over the past 30 years...
Ecstasy versus alcohol: Tolstoy and the variations of unhappinessA C Parrott
J Psychopharmacol 21:3-6; discussion 7. 2007
Effects of alcohol on subjective ratings of prospective and everyday memory deficitsJ Ling
Psychoology Section, University of Teesside, Middlesborough, United Kingdom
Alcohol Clin Exp Res 27:970-4. 2003..Research has shown that heavy alcohol use has a detrimental effect on retrospective memory. Less is known about the effect of alcohol on everyday memory...
