R W Parks

Summary

Affiliation: University of Edinburgh
Country: UK

Publications

  1. pmc Refining the role of laparoscopy and laparoscopic ultrasound in the staging of presumed pancreatic head and ampullary tumours
    B N J Thomson
    Department of Clinical and Surgical Sciences Surgery, 51 Little France Crescent, Edinburgh, EH16 4SA, UK
    Br J Cancer 94:213-7. 2006
  2. pmc Early career choices and successful career progression in surgery in the UK: prospective cohort studies
    Michael J Goldacre
    UK Medical Careers Research Group, Department of Public Health, Oxford University, Oxford, UK
    BMC Surg 10:32. 2010
  3. pmc Management of pancreatic pseudocysts
    R W Parks
    Surgical Unit, Mater Hospital, Belfast, UK
    Ann R Coll Surg Engl 82:383-7. 2000
  4. pmc Benefits of specialisation in the management of pancreatic cancer: results of a Scottish population-based study
    R W Parks
    Department of Clinical and Surgical Sciences, The University of Edinburgh, Royal Infirmary, 51 Little France Crescent, Edinburgh EH16 4SA, UK
    Br J Cancer 91:459-65. 2004
  5. ncbi request reprint Prognostic factors in the palliation of pancreatic cancer
    F J F Engelken
    Department of Clinical and Surgical Sciences Surgery, The University of Edinburgh, Royal Infirmary of Edinburgh, Lauriston Place, Edinburgh, EH3 9YW, UK
    Eur J Surg Oncol 29:368-73. 2003
  6. ncbi request reprint Host immune responses and intestinal permeability in patients with jaundice
    R W Parks
    Department of Surgery, Queen s University of Belfast, Northern Ireland, UK
    Br J Surg 90:239-45. 2003
  7. ncbi request reprint Changes in gastrointestinal morphology associated with obstructive jaundice
    R W Parks
    Department of Surgery, The Queen s University of Belfast, Northern Ireland, UK
    J Pathol 192:526-32. 2000
  8. ncbi request reprint Palliation for suspected unresectable hilar cholangiocarcinoma
    S Connor
    Department of Clinical and Surgical Sciences Surgery, University of Edinburgh, Royal Infirmary, Edinburgh EH16 4SA, UK
    Eur J Surg Oncol 33:341-5. 2007
  9. ncbi request reprint Glutamine improves intestinal barrier function in experimental biliary obstruction
    J S White
    Department of Surgery, School of Medicine, Queen s University of Belfast, Belfast, UK
    Eur Surg Res 37:342-7. 2005
  10. ncbi request reprint Liver resection and transplantation in the management of iatrogenic biliary injury
    B N J Thomson
    Department of Clinical and Surgical Sciences Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK
    World J Surg 31:2363-9. 2007

Detail Information

Publications44

  1. pmc Refining the role of laparoscopy and laparoscopic ultrasound in the staging of presumed pancreatic head and ampullary tumours
    B N J Thomson
    Department of Clinical and Surgical Sciences Surgery, 51 Little France Crescent, Edinburgh, EH16 4SA, UK
    Br J Cancer 94:213-7. 2006
    ..The remaining patient was deemed unfit for resection. Selective use of laparoscopic ultrasound is indicated in the staging of periampullary tumours with CT grades A to D...
  2. pmc Early career choices and successful career progression in surgery in the UK: prospective cohort studies
    Michael J Goldacre
    UK Medical Careers Research Group, Department of Public Health, Oxford University, Oxford, UK
    BMC Surg 10:32. 2010
    ..We studied trends in career choices for surgery, and the eventual career destinations, of UK graduates who declared an early preference for surgery...
  3. pmc Management of pancreatic pseudocysts
    R W Parks
    Surgical Unit, Mater Hospital, Belfast, UK
    Ann R Coll Surg Engl 82:383-7. 2000
    ..This review analyses the outcome for patients with acute and chronic pancreatic pseudocysts managed in two major referral centres...
  4. pmc Benefits of specialisation in the management of pancreatic cancer: results of a Scottish population-based study
    R W Parks
    Department of Clinical and Surgical Sciences, The University of Edinburgh, Royal Infirmary, 51 Little France Crescent, Edinburgh EH16 4SA, UK
    Br J Cancer 91:459-65. 2004
    ..Specialisation and concentration of cancer care has major implications for the delivery of health services...
  5. ncbi request reprint Prognostic factors in the palliation of pancreatic cancer
    F J F Engelken
    Department of Clinical and Surgical Sciences Surgery, The University of Edinburgh, Royal Infirmary of Edinburgh, Lauriston Place, Edinburgh, EH3 9YW, UK
    Eur J Surg Oncol 29:368-73. 2003
    ..The aim is to evaluate the prognostic significance of clinical and laboratory variables in patients with unresectable pancreatic cancer...
  6. ncbi request reprint Host immune responses and intestinal permeability in patients with jaundice
    R W Parks
    Department of Surgery, Queen s University of Belfast, Northern Ireland, UK
    Br J Surg 90:239-45. 2003
    ..The aims of these studies were to assess the systemic immune response to intervention in patients with jaundice and to compare the effects of surgical and non-surgical biliary drainage on host immune function and gut barrier function...
  7. ncbi request reprint Changes in gastrointestinal morphology associated with obstructive jaundice
    R W Parks
    Department of Surgery, The Queen s University of Belfast, Northern Ireland, UK
    J Pathol 192:526-32. 2000
    ..Significant bacterial translocation occurs following bile duct ligation and this supports the hypothesis of gut barrier dysfunction with obstructive jaundice...
  8. ncbi request reprint Palliation for suspected unresectable hilar cholangiocarcinoma
    S Connor
    Department of Clinical and Surgical Sciences Surgery, University of Edinburgh, Royal Infirmary, Edinburgh EH16 4SA, UK
    Eur J Surg Oncol 33:341-5. 2007
    ..The aim of this study was to evaluate the outcome of different techniques of palliation for patients with hilar cholangiocarcinoma...
  9. ncbi request reprint Glutamine improves intestinal barrier function in experimental biliary obstruction
    J S White
    Department of Surgery, School of Medicine, Queen s University of Belfast, Belfast, UK
    Eur Surg Res 37:342-7. 2005
    ..To determine the effects of enteral administration of glutamine on intestinal barrier function in experimental biliary obstruction...
  10. ncbi request reprint Liver resection and transplantation in the management of iatrogenic biliary injury
    B N J Thomson
    Department of Clinical and Surgical Sciences Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK
    World J Surg 31:2363-9. 2007
    ..Biliary injury during cholecystectomy can be managed successfully by biliary reconstruction in the majority of patients; however, a proportion of patients may require hepatic resection or even liver transplantation...
  11. ncbi request reprint The probiotic bacterium Lactobacillus plantarum species 299 reduces intestinal permeability in experimental biliary obstruction
    J S White
    Department of Surgery, School of Medicine, Queen s University of Belfast, Belfast, UK
    Lett Appl Microbiol 42:19-23. 2006
    ..Significance and Impact of the Study: This study provides insight to direct further work into the modulation of intestinal barrier function by probiotic bacteria...
  12. ncbi request reprint Surgery for colorectal liver metastases
    S J McNally
    Department of Clinical Surgery, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, UK
    Dig Surg 30:337-47. 2013
    ..The majority of patients with hepatic metastases should be considered for resectional surgery, if all disease can be resected, as this offers the only opportunity for prolonged survival. ..
  13. ncbi request reprint Follow-up and outcomes for resection of colorectal liver metastases in Edinburgh
    S Connor
    Division of Clinical and Surgical Sciences Surgery, University of Edinburgh, Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, United Kingdom
    Eur J Surg Oncol 33:55-60. 2007
    ..The aim of this study was to assess the value of a defined follow-up protocol for patients undergoing potentially curative hepatic resection for colorectal hepatic metastases...
  14. doi request reprint The selective use of magnetic resonance cholangiopancreatography in the imaging of the axial biliary tree in patients with acute gallstone pancreatitis
    R Mofidi
    Department of Clinical and Surgical Sciences Surgery, University of Edinburgh, Edinburgh, UK
    Pancreatology 8:55-60. 2008
    ..The aim of this study was to assess the impact following the introduction of MRCP in the management of AGP in a tertiary referral unit...
  15. pmc Postchemoembolisation syndrome--tumour necrosis or hepatocyte injury?
    S J Wigmore
    Department of Clinical and Surgical Sciences Surgery, University of Edinburgh, Royal Infirmary, SI Little France Crescent, Edinburgh EH16 4SA, UK
    Br J Cancer 89:1423-7. 2003
    ..There is no evidence that either a postchemoembolisation fever or cytolysis is associated with an enhanced tumour response or improved long-term survival in patients with primary or secondary liver cancer...
  16. doi request reprint Risk assessment in acute pancreatitis
    R Mofidi
    Department of Clinical and Surgical Sciences Surgery, University of Edinburgh, Edinburgh, UK
    Br J Surg 96:137-50. 2009
    ..Acute pancreatitis has a variable natural history and in a proportion of patients is associated with severe complications and a significant risk of death. The various tools available for risk assessment in acute pancreatitis are reviewed...
  17. ncbi request reprint Predicting survival in patients with hepatocellular carcinoma: a UK perspective
    J W C Kung
    Department of Clinical and Surgical Sciences Surgery, Royal Infirmary of Edinburgh, University of Edinburgh, Ward 106 Room F3307, 51 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SA, UK
    Eur J Surg Oncol 33:188-94. 2007
    ..The aim of this study was to compare the Okuda, Cancer of the Liver Italian Program (CLIP), and Barcelona Clinic Liver Cancer (BCLC) classifications as predictors of survival in UK patients with HCC...
  18. ncbi request reprint Predicting survival in patients with liver cancer considered for transarterial chemoembolization
    S J Wigmore
    Department of Clinical and Surgical Science, University of Edinburgh, Royal Infirmary of Edinburgh, 51 Little France Crescent, EH16 4SA Edinburgh, UK
    Eur J Surg Oncol 30:41-5. 2004
    ..This study attempts to identify patients with liver cancer most likely to benefit from this type of treatment...
  19. doi request reprint The relationship between hospital volume and post-operative mortality rates for upper gastrointestinal cancer resections: Scotland 1982-2003
    R J E Skipworth
    Clinical and Surgical Sciences Surgery, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, EH16 4SA, UK
    Eur J Surg Oncol 36:141-7. 2010
    ..Centralisation of surgical treatment of cancer has resulted in improved outcomes. We aimed to determine evidence of benefit for specialised management of upper gastrointestinal cancer in high-volume centres in Scotland...
  20. ncbi request reprint Prognostic factors in patients undergoing surgery for severe necrotizing pancreatitis
    R Mofidi
    Department of Clinical and Surgical Sciences, University of Edinburgh, Royal Infirmary of Edinburgh, Old Dalkeith Road, Edinburgh, UK
    World J Surg 31:2002-7. 2007
    ..Necrosectomy is associated with poorer outcome when performed within 2 weeks of presentation...
  21. ncbi request reprint Association between early systemic inflammatory response, severity of multiorgan dysfunction and death in acute pancreatitis
    R Mofidi
    Department of Clinical and Surgical Sciences, University of Edinburgh, Royal Infirmary of Edinburgh, Old Dalkeith Road, Edinburgh EH16 4SA, UK
    Br J Surg 93:738-44. 2006
    ..The aim of this study was to assess the significance of early systemic inflammatory response syndrome (SIRS) in the development of multiorgan dysfunction syndrome (MODS) and death from acute pancreatitis...
  22. ncbi request reprint The extent of resection influences outcome following hepatectomy for colorectal liver metastases
    G D Stewart
    Department of Clinical and Surgical Sciences Surgery, Royal Infirmary of Edinburgh, University of Edinburgh, 51 Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SA, UK
    Eur J Surg Oncol 30:370-6. 2004
    ..This has resulted in not only more extensive resections, but more atypical and bilobar resections. The aim of this study was to compare the outcome of patients undergoing different extent of liver resection in a specialist unit...
  23. ncbi request reprint Palliation of pancreatic neoplasms
    B N J Thomson
    Department of Clinical and Surgical Sciences Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK
    Minerva Chir 59:113-22. 2004
    ..Prognostic factors such as histopathology, presence of metastatic disease and C reactive protein levels may allow better prediction of survival, therefore aiding selection of the most appropriate palliative techniques...
  24. doi request reprint Randomized clinical trial of laxatives and oral nutritional supplements within an enhanced recovery after surgery protocol following liver resection
    P O Hendry
    Clinical and Surgical Sciences Surgery, Royal Infirmary, Edinburgh, UK
    Br J Surg 97:1198-206. 2010
    ..Combined with carbohydrate loading and oral nutritional supplements (ONS), it may further enhance recovery of gastrointestinal function and promote earlier overall recovery...
  25. ncbi request reprint Early specialist repair of biliary injury
    B N J Thomson
    Department of Clinical and Surgical Sciences Surgery, Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, UK
    Br J Surg 93:216-20. 2006
    ..In the absence of sepsis or significant peritoneal soiling, repair within the first week may be optimal. This study compared the outcome of early (within the first 2 weeks) and delayed (between 2 weeks and 6 months) repair...
  26. pmc Guidelines for resection of colorectal cancer liver metastases
    O J Garden
    Clinical and Surgical Sciences Surgery, University of Edinburgh, Royal Infirmary, 51 Little France Crescent, Edinburgh EH16 4SA, UK
    Gut 55:iii1-8. 2006
  27. ncbi request reprint Patterns of bacterial translocation in experimental biliary obstruction
    J S White
    Department of Surgery, School of Medicine, Queen s University of Belfast, Belfast, United Kingdom
    J Surg Res 132:80-4. 2006
    ..The aim of this study was to estimate the extent and pattern of bacterial translocation in experimental biliary obstruction...
  28. doi request reprint Intraoperative cholangiography in modern surgical practice
    Deepika Akolekar
    Department of Surgery, Royal Infirmary of Edinburgh, Edinburgh, UK
    Dig Surg 26:130-4. 2009
    ..The aim of this study was to assess the practice of performing intraoperative cholangiography (IOC) during laparoscopic cholecystectomy in a busy teaching hospital...
  29. ncbi request reprint Open cholecystectomy in the laparoscopic era
    P J Jenkins
    Clinical and Surgical Sciences Surgery, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, UK
    Br J Surg 94:1382-5. 2007
    ..As techniques in laparoscopic cholecystectomy have improved, surgeon experience of open cholecystectomy may be limited. This study examined the current indications for and techniques used in primary open cholecystectomy...
  30. ncbi request reprint What proportion of basic surgical trainees continue in a surgical career? A survey of the factors which are important in influencing career decisions
    J M J Richards
    Department of Clinical and Surgical Sciences Surgery, University of Edinburgh, Little France Crescent
    Surgeon 7:270-5. 2009
    ..There is little information available on the factors involved in career choices amongst surgical trainees and this study aimed to address this issue...
  31. doi request reprint Prognostic models for predicting death after hepatectomy in individuals with hepatic metastases from colorectal cancer
    M D Smith
    Department of Clinical and Surgical Sciences Surgery, Royal Infirmary of Edinburgh, University of Edinburgh, Edinburgh, EH16 4SA, UK
    World J Surg 32:1108-9. 2008
  32. ncbi request reprint Treatment of hepatic metastases of neuroendocrine malignancies: a 10-year experience
    C H C Dejong
    Department of Clinical and Surgical Sciences, Royal Infirmary, Edinburgh, Scotland
    J R Coll Surg Edinb 47:495-9. 2002
    ..Accepted management options include administration of somatostatin-analogues, selective chemoembolisation or hepatic resection. The aim of this study was to review the management of hepatic neuroendocrine metastases in our unit...
  33. doi request reprint Outcomes following a dedicated period of research during surgical training
    B M Stutchfield
    Clinical and Surgical Sciences Surgery, University of Edinburgh, Edinburgh, Scotland, UK
    Scott Med J 56:206-9. 2011
    ..A period of dedicated research was thought necessary for career progression, but few thought dedicated research should be integral to surgical training...
  34. ncbi request reprint The administration of an oral carbohydrate-containing fluid prior to major elective upper-gastrointestinal surgery preserves skeletal muscle mass postoperatively--a randomised clinical trial
    K A Yuill
    Department of Clinical and Surgical Sciences, Royal Infirmary of Edinburgh, Edinburgh, UK
    Clin Nutr 24:32-7. 2005
    ..The aims of this study were to assess the tolerance of preoperative carbohydrate fluid administration and to determine its effect on postoperative metabolic and clinical responses...
  35. ncbi request reprint Glutathione supplementation to University of Wisconsin solution causes endothelial dysfunction
    A L Tambyraja
    Clinical and Surgical Sciences Surgery, Royal Infirmary of Edinburgh, 51 Little France Crescent, University of Edinburgh, Edinburgh, EH16 4SA, UK
    Transpl Immunol 18:146-50. 2007
    ..This study assesses the effect of GSH-supplementation on endothelial function in tissues subjected to cold ischaemia and compares its effects to a mono-ethyl ester equivalent (GSH-MEE) and S-nitrosated GSH (GSNO)...
  36. pmc Cholangiocarcinoma arising after biliary-enteric drainage procedures for benign disease
    V Bettschart
    Department of Clinical and Surgical Sciences Surgery, University of Edinburgh and Scottish Liver Transplant Unit, Royal Infirmary of Edinburgh, Edinburgh, UK
    Gut 51:128-9. 2002
  37. ncbi request reprint Interstitial ablative techniques for hepatic tumours
    C Erce
    Department of Clinical and Surgical Sciences Surgery, University of Edinburgh, Edinburgh, UK
    Br J Surg 90:272-89. 2003
    ..Most patients with liver tumours are not suitable for surgery but interstitial ablative techniques may control disease progression and improve survival rates...
  38. doi request reprint Traumatic injury to the colon and rectum in Scotland: demographics and outcome
    R R Brady
    Department of Surgery, Queen Margaret Hospital, NHS Fife, Scotland, UK
    Colorectal Dis 14:e16-22. 2012
    ..An analysis of a multi-centred database of trauma patients was performed...
  39. ncbi request reprint A population-based study of pancreatic trauma in Scotland
    John M Scollay
    Department of Clinical and Surgical Sciences Surgery, University of Edinburgh, Scotland, UK
    World J Surg 30:2136-41. 2006
    ..The aim of this population-based study was to assess the incidence, mechanisms, management and outcome of patients who sustained pancreatic trauma in Scotland over the period 1992-2002...
  40. ncbi request reprint Incidence of benign pathology in patients undergoing hepatic resection for suspected malignancy
    R A E Clayton
    Department of Clinical and Surgical Sciences Surgery Royal Infirmary of Edinburgh
    Surgeon 1:32-8. 2003
    ..The aim of this study was to establish whether improvements in pre-operative staging might better identify this patient population...
  41. ncbi request reprint An audit of the management of patients with acute pancreatitis against national standards of practice
    R Mofidi
    Department of Clinical and Surgical Sciences, University of Edinburgh, Edinburgh UK
    Br J Surg 94:844-8. 2007
    ..The aim of this study was to audit the management of patients with acute pancreatitis against the standards of practice in the British Society of Gastroenterology guidelines...
  42. pmc Impairment of Gag-specific CD8(+) T-cell function in mucosal and systemic compartments of simian immunodeficiency virus mac251- and simian-human immunodeficiency virus KU2-infected macaques
    Z Hel
    Basic Research Laboratory, Bethesda, Maryland 20892, USA
    J Virol 75:11483-95. 2001
    ..The data obtained in this pilot study lead to the hypothesis that disease progression may be associated with loss of virus-specific CD8(+) T-cell function...
  43. ncbi request reprint Pre-operative high sensitivity C-reactive protein and postoperative outcome in patients undergoing elective orthopaedic surgery
    G L Ackland
    Anaesthesia and Critical Care Medicine, Centre for Anaesthesia, Critical Care and Pain Management, University College London, London, UK
    Anaesthesia 62:888-94. 2007
    ..5-6.5; p = 0.03; log rank test). In 21 patients with > 8 days length of stay, high pre-operative hsCRP patients were over-represented (p = 0.04). Pre-operative hsCRP is related to length of stay and delayed postoperative complications...
  44. ncbi request reprint Presentation, treatment and outcome in patients with ampullary tumours
    V Bettschart
    Department of Surgery, Sherbrooke University, Sherbrooke, Quebec, Canada
    Br J Surg 91:1600-7. 2004
    ..The aim of this study was to analyse outcome and determine predictors of survival for patients with ampullary tumours treated in a specialist centre...