Jennifer C Palmer

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. doi request reprint Endothelin-converting enzyme-1 activity, endothelin-1 production, and free radical-dependent vasoconstriction in Alzheimer's disease
    Jennifer C Palmer
    University of Bristol, Dementia Research Group, Frenchay Hospital, Bristol, UK
    J Alzheimers Dis 36:577-87. 2013
  2. doi request reprint Endothelin-1 is elevated in Alzheimer's disease and upregulated by amyloid-β
    Jennifer C Palmer
    Dementia ResearchGroup, School of Clinical Sciences, University of Bristol, Frenchay Hospital, Bristol, UK
    J Alzheimers Dis 29:853-61. 2012
  3. pmc Endothelin-converting enzyme-2 is increased in Alzheimer's disease and up-regulated by Abeta
    Jennifer C Palmer
    Dementia Research Group, Frenchay Hospital, Bristol, United Kingdom
    Am J Pathol 175:262-70. 2009
  4. doi request reprint Endothelin-converting enzyme-1 in Alzheimer's disease and vascular dementia
    J C Palmer
    Clinical Science at North Bristol, University of Bristol, Dementia Research Group, Frenchay Hospital, Bristol, UK
    Neuropathol Appl Neurobiol 36:487-97. 2010
  5. doi request reprint Endothelin receptor antagonists: potential in Alzheimer's disease
    Jennifer Palmer
    Dementia Research Group, Institute of Clinical Neurosciences, School of Clinical Sciences, University of Bristol, Frenchay Hospital, Bristol BS16 1LE, United Kingdom
    Pharmacol Res 63:525-31. 2011

Detail Information

Publications5

  1. doi request reprint Endothelin-converting enzyme-1 activity, endothelin-1 production, and free radical-dependent vasoconstriction in Alzheimer's disease
    Jennifer C Palmer
    University of Bristol, Dementia Research Group, Frenchay Hospital, Bristol, UK
    J Alzheimers Dis 36:577-87. 2013
    ..Our findings indicate that cerebral vasoconstriction induced by Aβ results in part from a free radical-mediated increase in ECE-1 activity and ET-1 production. ..
  2. doi request reprint Endothelin-1 is elevated in Alzheimer's disease and upregulated by amyloid-β
    Jennifer C Palmer
    Dementia ResearchGroup, School of Clinical Sciences, University of Bristol, Frenchay Hospital, Bristol, UK
    J Alzheimers Dis 29:853-61. 2012
    ..024). These findings provide evidence of overactivity of the endothelin system in AD, further supporting the suggestion that endothelin receptor antagonists may be of value for the treatment of this disease...
  3. pmc Endothelin-converting enzyme-2 is increased in Alzheimer's disease and up-regulated by Abeta
    Jennifer C Palmer
    Dementia Research Group, Frenchay Hospital, Bristol, United Kingdom
    Am J Pathol 175:262-70. 2009
    ..Our findings suggest that endothelin-1 receptor antagonists, already licensed for treating other diseases, could be of benefit in AD therapies...
  4. doi request reprint Endothelin-converting enzyme-1 in Alzheimer's disease and vascular dementia
    J C Palmer
    Clinical Science at North Bristol, University of Bristol, Dementia Research Group, Frenchay Hospital, Bristol, UK
    Neuropathol Appl Neurobiol 36:487-97. 2010
    ..In vitro, expression of ECE-2 was upregulated by Aβ. Our aims for this study were to examine expression of ECE-1 (which has 57% homology with ECE-2) in temporal cortex from patients with AD, vascular dementia (VaD) and controls...
  5. doi request reprint Endothelin receptor antagonists: potential in Alzheimer's disease
    Jennifer Palmer
    Dementia Research Group, Institute of Clinical Neurosciences, School of Clinical Sciences, University of Bristol, Frenchay Hospital, Bristol BS16 1LE, United Kingdom
    Pharmacol Res 63:525-31. 2011
    ....