Research Topics
| Lena PalaniyappanSummaryAffiliation: University of Nottingham Country: UK Publications
| Collaborators |
Detail Information
Publications
Gyrification of Broca's region is anomalously lateralized at onset of schizophrenia in adolescence and regresses at 2year follow-upL Palaniyappan
Division of Psychiatry, Institute of Mental Health, University of Nottingham, Nottingham NG7 2TU, UK Nottinghamshire Healthcare NHS Trust, Nottingham, UK Electronic address
Schizophr Res 147:39-45. 2013..A deviation in the lateralized development of peri-Sylvian areas for language production and comprehension appears critical to the pathophysiology of schizophrenia and may point to its species-specific origin...
The concept of salience network dysfunction in schizophrenia: from neuroimaging observations to therapeutic opportunitiesL Palaniyappan
Division of Psychiatry, Institute of Mental Health, University of Nottingham, Nottingham, UK
Curr Top Med Chem 12:2324-38. 2012..This combination approach, termed as Brain Network Modulation, could exploit neuronal plasticity to reverse a key pathophysiological deficit in schizophrenia...
Aberrant cortical gyrification in schizophrenia: a surface-based morphometry studyLena Palaniyappan
Division of Psychiatry, University of Nottingham, South Block, Queen s Medical Centre, Nottingham, United Kingdom
J Psychiatry Neurosci 37:399-406. 2012..Investigating the anatomic distribution of gyrification defects can provide important information about neurodevelopment in patients with schizophrenia...- The neuroanatomy of psychotic diathesis: a meta-analytic reviewLena Palaniyappan
Division of Psychiatry, University of Nottingham, A Floor, South Block, Queen s Medical Centre, Nottingham NG7 2UH, United Kingdom
J Psychiatr Res 46:1249-56. 2012..It is unclear which of these neuroanatomical changes are associated with a predisposition or vulnerability to develop schizophrenia rather than the appearance of the clinical features of the illness... - Dissociable morphometric differences of the inferior parietal lobule in schizophreniaLena Palaniyappan
Division of Psychiatry, University of Nottingham, Queen s Medical Centre, UK
Eur Arch Psychiatry Clin Neurosci 262:579-87. 2012.... - Structural correlates of auditory hallucinations in schizophrenia: a meta-analysisLena Palaniyappan
Division of Psychiatry, University of Nottingham, A Floor, South Block, Queen s Medical Centre, Nottingham, NG7 2UH, UK
Schizophr Res 137:169-73. 2012..Despite being one of the most common symptoms of schizophrenia, determining the neural correlates of auditory hallucinations still remains elusive with various studies providing inconsistent results... - Differential effects of surface area, gyrification and cortical thickness on voxel based morphometric deficits in schizophreniaLena Palaniyappan
Division of Psychiatry, University of Nottingham, A Floor, South Block, Queen s Medical Centre, Nottingham, NG7 2UH, UK
Neuroimage 60:693-9. 2012.... - Does the salience network play a cardinal role in psychosis? An emerging hypothesis of insular dysfunctionLena Palaniyappan
Division of Psychiatry, University of Nottingham, Queen s Medical Centre, Nottingham, United Kingdom
J Psychiatry Neurosci 37:17-27. 2012..In this review, we bring together evidence from imaging studies to understand the role of the salience network in schizophrenia and propose a model of insular dysfunction in psychosis... - Regional contraction of brain surface area involves three large-scale networks in schizophreniaLena Palaniyappan
Division of Psychiatry, University of Nottingham, A Floor, South Block, Queen s Medical Centre, Nottingham, NG7 2UH, United Kingdom
Schizophr Res 129:163-8. 2011..Our findings suggest that a fundamental disturbance in cortical expansion is likely in individuals who develop schizophrenia... - Folding of the prefrontal cortex in schizophrenia: regional differences in gyrificationLena Palaniyappan
Division of Psychiatry, University of Nottingham, Queen s Medical Centre, Nottingham, United Kingdom
Biol Psychiatry 69:974-9. 2011..With surface reconstructions from magnetic resonance imaging, we studied the gyrification within anatomically meaningful subdivisions of prefrontal cortex in schizophrenia... - Appreciating symptoms and deficits in schizophrenia: right posterior insula and poor insightLena Palaniyappan
Division of Psychiatry, University of Nottingham, A Floor, South Block, Queen s Medical Centre, Nottingham, NG7 2UH, United Kingdom
Prog Neuropsychopharmacol Biol Psychiatry 35:523-7. 2011..Abnormalities in interoceptive awareness and self-appraisal of emotional states may contribute to the loss of insight seen in schizophrenia... - Reality distortion is related to the structure of the salience network in schizophreniaL Palaniyappan
Division of Psychiatry, University of Nottingham, A Floor, South Block, Queen s Medical Centre, Nottingham, UK
Psychol Med 41:1701-8. 2011..We investigated whether structural deficits in the salience network are associated with the reality distortion seen in schizophrenia...