Santa Jeremy Ono
Affiliation: University College London
- Immunity in the eye: lessons in organ-specific responsesSanta Jeremy Ono
Department of Immunology, University College London, University of London, Institutes of Ophthalmology and Child Health and Moorfields Eye Hospital, United Kingdom
J Leukoc Biol 74:149-50. 2003..Here, we highlight some of the findings discussed at the meeting and introduce in-depth reviews published in this issue of the journal...
- The birth of transplantation immunology: the Billingham-Medawar experiments at Birmingham University and University College London. 1951Santa Jeremy Ono
University College London
J Exp Biol 207:4013-4. 2004
- Allergic conjunctivitis: update on pathophysiology and prospects for future treatmentSanta Jeremy Ono
Department of Immunology, University College London, Institutes of Ophthalmology and Child Health and Moorfields Eye Hospital, NHS Trust, United Kingdom
J Allergy Clin Immunol 115:118-22. 2005....
- Role of CC chemokines and their receptors in multiple aspects of mast cell biology: comparative protein profiling of FcepsilonRI- and/or CCR1-engaged mast cells using protein chip technologyMasako Toda
Department of Immunology, Institutes of Ophthalmology and Child Health, University College London, London EC1V 9EL, UK
Novartis Found Symp 271:131-40; discussion 140-51. 2005..We also discuss our view of the role of CC chemokines and CCRs in regulating multiple aspects of mast cell biology...
- Macrophage inflammatory protein-1alpha as a costimulatory signal for mast cell-mediated immediate hypersensitivity reactionsDai Miyazaki
Department of Immunology, University College London, University of London, Institutes of Ophthalmology and Child Health, London, United Kingdom
J Clin Invest 115:434-42. 2005..Antagonizing the interaction of MIP-1alpha with its receptor CC chemokine receptor 1 (CCR1) or signal transduction from CCR1 may therefore prove to be effective as an antiinflammatory therapy on the ocular surface...
- Inhibition of MHC class II gene expression in uveal melanoma cells is due to methylation of the CIITA gene or an upstream activatorMichael Radosevich
Department of Immunology, University College London, Institute of Ophthalmology and Child Health and Moorfields Eye Hospital, 11 43 Bath Street, London, EC1V 9EL, UK
Exp Mol Pathol 82:68-76. 2007....
- Novel mechanisms of class II major histocompatibility complex gene regulationMichael Radosevich
Department of Immunology, Institute of Ophthalmology, University College London, University of London, London, UK
Immunol Res 27:85-106. 2003..This communication outlines recent advances in this field and discusses likely areas for future research...
- Detailed criteria for the assessment of clinical symptoms in a new murine model of severe allergic conjunctivitisTakao Nakamura
Department of Immunology, Institutes of Ophthalmology and Child Health, University College London, University of London, London, UK
Cornea 22:S13-8. 2003....
- Dynamic changes in conjunctival dendritic cell numbers, anatomical position and phenotype during experimental allergic conjunctivitisMasaharu Ohbayashi
Department of Ophthalmology and Medicine, Emory University School of Medicine and Emory Eye Center, Atlanta, GA 30322, USA
Exp Mol Pathol 83:216-23. 2007..These results indicate that conjunctival DC subsets may play an important role in the immune-regulatory processes involved in the inflammatory component of allergic conjunctivitis...
- Role of beta-chemokines in mast cell activation and type I hypersensitivity reactions in the conjunctiva: in vivo and in vitro studiesFrederick Beer
Emory University School of Medicine, Emory Eye Center, Atlanta, GA, USA
Immunol Rev 217:96-104. 2007..Data are also presented that suggest that Fc epsilon RI:chemokine receptor cross talk may involve spatiotemporal dynamics that may control the strength and nature of the complex activating signals controlling mast cell effector function...
- A specific CCR3 chemokine receptor antagonist inhibits both early and late phase allergic inflammation in the conjunctivaTakao Nakamura
Department of Immunology University College London University of London Institutes of Ophthalmology and Child Health and Moorfields Eye Hospital London, EC1V 9EL, United Kingdom
Immunol Res 33:213-21. 2005..These results constitute the first direct evidence that antagonism of CCR3 has clear potential for the treatment of allergic diseases...
- The dendritic cell in allergic conjunctivitisBita Manzouri
Institute of Ophthalmology, Moorfields Eye Hospital, London, UK
Ocul Surf 6:70-8. 2008..We review what has been learned from studies of both human ocular allergy and murine models and comment on how this compares to allergic reactions in other mucosal tissues...