J J Oliver
Affiliation: University of Edinburgh
- Venlafaxine poisoning complicated by a late rise in creatine kinase: two case reportsJ J Oliver
Scottish Poisons Information Bureau, NPIS Edinburgh, Royal Infirmary, UK
Hum Exp Toxicol 21:463-6. 2002..Although the clinical consequences were not serious, physicians should be alerted to the possibility of delayed rhabdomyolysis or serotonin syndrome in patients who have taken venlafaxine in overdose...
- Noninvasive assessment of arterial stiffness and risk of atherosclerotic eventsJames J Oliver
Clinical Pharmacology Unit and Research Centre, University of Edinburgh, Western General Hospital, Crewe Road South, Edinburgh EH4 2XU, Scotland, UK
Arterioscler Thromb Vasc Biol 23:554-66. 2003..Finally, the effects of current and future cardiovascular drugs on arterial stiffness are also discussed, as is the relationship between arterial elasticity and endothelial function...
- Stimulated tissue plasminogen activator release as a marker of endothelial function in humansJames J Oliver
Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK
Arterioscler Thromb Vasc Biol 25:2470-9. 2005..The investigation of endothelial fibrinolytic function has the potential to provide major new insights into the pathophysiology of cardiovascular disease, and to shape future therapeutic interventions...
- Patterns and predictors of re-admission to hospital with self-poisoning in ScotlandR A Payne
Queen s Medical Research Institute, Clinical Pharmacology Unit, University of Edinburgh, 47 Little France Crescent, Edinburgh EH164TJ, UK
Public Health 123:134-7. 2009..To identify factors influencing hospital re-admission with self-poisoning...
- Poisons admissions in Edinburgh 1981-2001: agent trends and predictors of hospital readmissionsS B Rafnsson
Department of Public Health Sciences, University of Edinburgh Medical School, Teviot Place, EH8 9AG, Edinburgh, UK
Hum Exp Toxicol 26:49-57. 2007..Information on drug type used in self-poisoning may assist in identifying patients at risk for future events, and in reducing hospital readmissions...
- No adverse hemodynamic interaction between sildenafil and red wineStephen J Leslie
Centre for Cardiovascular Science, The University of Edinburgh, Western General Hospital, United Kingdom
Clin Pharmacol Ther 76:365-70. 2004..Alcohol is a commonly used recreational substance with complex vascular effects, which may, in part, be mediated by nitric oxide. Thus there is potential for an adverse hemodynamic interaction...
- Endothelial fibrinolytic function in hypertension: the expanding storyJames J Oliver
J Hypertens 23:1471-2. 2005
- Effect of regular phosphodiesterase type 5 inhibition in hypertensionJames J Oliver
University of Edinburgh, United Kingdom
Hypertension 48:622-7. 2006..In conclusion, regular sildenafil constitutes effective antihypertensive therapy. Further studies are warranted to evaluate the role of longer-acting phosphodiesterase type 5 inhibitors as antihypertensive agents in clinical practice...
- Dose-response relationship of sublingual nitroglycerin with brachial artery dilatation and change in central and peripheral augmentation indexJames J Oliver
Clin Pharmacol Ther 77:337-8. 2005
- Endothelial function and dysfunction. Part I: Methodological issues for assessment in the different vascular beds: a statement by the Working Group on Endothelin and Endothelial Factors of the European Society of HypertensionJohn Deanfield
Vascular Physiology Unit, Institute of Child Health and Great Ormond Street Hospital NHS Trust, London, UK
J Hypertens 23:7-17. 2005..Thus, the most relevant methodological issues in the research on endothelial function and dysfunction are summarized in this paper...
- Endothelial function and dysfunction. Part II: Association with cardiovascular risk factors and diseases. A statement by the Working Group on Endothelins and Endothelial Factors of the European Society of HypertensionHanspeter Brunner
Division of Cardiology, University Hospital, Basel, Switzerland
J Hypertens 23:233-46. 2005..This paper will provide a concise overview of the mechanisms causing endothelial dysfunction in the different cardiovascular risk factors and disease conditions, and of the impact of the intervention measures and treatments...
- Journals should select drug advertisements more carefullyJames J Oliver
BMJ 326:1211. 2003
- Contribution of the M3 muscarinic receptors to the vasodilator response to acetylcholine in the human forearm vascular bedTeresa M Attinà
Clinical Pharmacology Unit, Centre for Cardiovascular Science, Queen s edical Research Institute, University of Edinburgh, Edinburgh, Scottland, UK
Br J Clin Pharmacol 66:300-3. 2008..Darifenacin is a recently developed antimuscarinic drug with greater M(3) selectivity, and our main objective was to investigate whether darifenacin affects dose-dependent vasodilatation to ACh in the forearm circulation...