Research Topics
| D NuttSummaryAffiliation: University of Bristol Country: UK Publications
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Detail Information
Publications
Treatment of depression and concomitant anxietyD Nutt
Psychopharmacology Unit, School of Medical Sciences, University of Bristol, Bristol, UK
Eur Neuropsychopharmacol 10:S433-7. 2000..This paper will provide evidence to demonstrate the short- and long-term efficacy of SSRIs in the treatment of depression and comorbid anxiety, with most clinical evidence supporting the anxiolytic profile of the SSRI paroxetine...
Sleep disorders as core symptoms of depressionDavid Nutt
Psychopharmacology Unit, University of Bristol, UK
Dialogues Clin Neurosci 10:329-36. 2008..There is therefore a need for more successful management of sleep disturbance in depression, in order to improve quality of life in these patients and reduce an important factor in depressive relapse and recurrence...
Impulsiveness and the prolactin response to d-fenfluramineJ Evans
Division of Psychiatry, University of Bristol, UK
Psychopharmacology (Berl) 149:147-52. 2000..It is unknown whether this is because serotonin function plays a part in determining the dimension of trait impulsiveness in the general population or whether this is restricted to these behaviourally extreme groups...
Early onset anxiolytic efficacy after a single dose of pregabalin: double-blind, placebo- and active-comparator controlled evaluation using a dental anxiety modelD Nutt
Psychopharmacology Unit, University of Bristol, Bristol, UK
J Psychopharmacol 23:867-73. 2009..Additional research is needed to determine whether anxiolytic effect occurs in generalized anxiety disorder populations by day 1 or within 3-4 h post-first dose...
Alcohol and the brain. Pharmacological insights for psychiatristsD Nutt
Division of Psychiatry, School of Medical Sciences, University Walk, Bristol
Br J Psychiatry 175:114-9. 1999..A greater understanding of the brain mechanisms underlying the adverse effects of alcohol is now possible, thanks to significant research advances made over the past decade...
Acute carbon dioxide exposure in healthy adults: evaluation of a novel means of investigating the stress responseJ Kaye
University Research Centre for Neuroendocrinology, Bristol Royal Infirmary, Bristol, UK
J Neuroendocrinol 16:256-64. 2004..A single breath of 35% CO(2) safely and reliably produced sympathetic and HPA axis activation and should prove a useful addition to currently available laboratory tests of the human stress response...
Tryptophan depletion and its implications for psychiatryC Bell
Psychopharmacology Unit, School of Medical Sciences, Bristol, UK
Br J Psychiatry 178:399-405. 2001....
Establishing non-inferiority in treatment trials in psychiatry: guidelines from an Expert Consensus MeetingD Nutt
Psychopharmacology Unit, University of Bristol, Bristol, UK
J Psychopharmacol 22:409-16. 2008..This article presents the conclusions of this consensus and illustrates it using published data in the field of antidepressant treatment of generalized anxiety disorder...
Potential novel anxiolytic drugsD Christmas
Psychopharmacology Unit, University of Bristol, Level 5, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK
Curr Pharm Des 14:3534-46. 2008..We review GABA, serotonin, glutamate, noradrenaline, dopamine and some neuropeptides herein...
