Daniel H Nussey
Affiliation: University of Edinburgh
- Senescence in natural populations of animals: widespread evidence and its implications for bio-gerontologyDaniel H Nussey
Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, UK
Ageing Res Rev 12:214-25. 2013....
- Age-related variation in immunity in a wild mammal populationDaniel H Nussey
Centre for Immunity, Infection and Evolution, School of Biological Sciences, University of Edinburgh, UK
Aging Cell 11:178-80. 2012..Our findings suggest immune aging patterns observed in laboratory and domestic mammals may generalize to more complex, challenging environments and could have fitness costs under natural conditions...
- Patterns of body mass senescence and selective disappearance differ among three species of free-living ungulatesDaniel H Nussey
Institute of Evolutionary Biology, University of Edinburgh, The Kings Buildings, West Mains Road, Edinburgh EH9 3JT, United Kingdom
Ecology 92:1936-47. 2011..They also reveal that the pattern of senescence, and potentially also the processes underlying demographic declines in late life, can differ markedly across related species with similar life histories...
- Inter- and intrasexual variation in aging patterns across reproductive traits in a wild red deer populationDaniel H Nussey
Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, United Kingdom
Am Nat 174:342-57. 2009..Our results suggest that either natural selection or physiological constraint has caused an uncoupling of senescence rates in different physiological systems and, thus, different reproductive traits in this wild vertebrate population...
- Testing for genetic trade-offs between early- and late-life reproduction in a wild red deer populationDaniel H Nussey
Large Animal Research Group, Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK
Proc Biol Sci 275:745-50. 2008..Our results suggest rare support for the AP theory of ageing from a wild population...
- Fitness correlates of heritable variation in antibody responsiveness in a wild mammalAndrea L Graham
Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ 08544, USA
Science 330:662-5. 2010..Our results highlight the complex effects of natural selection on immune responsiveness and suggest that fitness trade-offs may maintain immunoheterogeneity, including genetic variation in autoimmune susceptibility...
- Evidence for a genetic basis of aging in two wild vertebrate populationsAlastair J Wilson
Institute of Evolutionary Biology, University of Edinburgh, West Mains Road, Edinburgh, EH9 3JT, United Kingdom
Curr Biol 17:2136-42. 2007..We find evidence that genetic differences among individuals cause variation in their rates of aging and that additive genetic variance for fitness increases with age, as predicted by the evolutionary theory of senescence...
- Inbreeding depression in red deer calvesCraig A Walling
Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, UK
BMC Evol Biol 11:318. 2011..We also tested whether inbreeding depression varied with environmental conditions and maternal age...
- Shared spatial effects on quantitative genetic parameters: accounting for spatial autocorrelation and home range overlap reduces estimates of heritability in wild red deerKatie V Stopher
Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, EH9 3JT, United Kingdom
Evolution 66:2411-26. 2012....
- The relationship between tooth wear, habitat quality and late-life reproduction in a wild red deer populationDaniel H Nussey
Department of Zoology, University of Cambridge, Downing Street, Cambridge, UK
J Anim Ecol 76:402-12. 2007..4. There was no evidence that females with more heavily worn molars had reduced reproductive performance late in life or that first molar height was associated with reproductive senescence...
- What is individual quality? An evolutionary perspectiveAlastair J Wilson
Institute of Evolutionary Biology, Ashworth Laboratories, University of Edinburgh, The King s Buildings, West Mains Road, Edinburgh EH9 3JT, UK
Trends Ecol Evol 25:207-14. 2010..We also propose a novel approach that is consistent with all current ecological uses, but also allows the concept of quality to be integrated with existing evolutionary theory...
- An ecologist's guide to the animal modelAlastair J Wilson
Wild Evolution Group, Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, EH9 3JT, UK
J Anim Ecol 79:13-26. 2010....
- Age-related variation in reproductive traits in the wandering albatross: evidence for terminal improvement following senescenceHannah Froy
Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK
Ecol Lett 16:642-9. 2013..Whilst highlighting the importance of breeding experience, we reveal senescent declines in performance are followed by a striking increase in breeding success and a key parental investment trait at the final breeding attempt...
- Selection on heritable phenotypic plasticity in a wild bird populationDaniel H Nussey
Netherlands Institute of Ecology NIOO KNAW, Post Office Box 40, 6666 ZG Heteren, Netherlands
Science 310:304-6. 2005..This temporal trend is concurrent with climate change causing a mismatch between the breeding times of the birds and their caterpillar prey. Continued selection on plasticity can act to alleviate this mismatch...
- Osteoarthritis of the temporo-mandibular joint in free-living Soay sheep on St KildaColin Arthur
Institute of Evolutionary Biology, University of Edinburgh, Ashworth Laboratories, The King s Buildings, West Mains Road, Edinburgh EH9 3JT, UK
Vet J 203:120-5. 2015..Although there were trends towards lower fecundity and lower lamb birth weight in the breeding season prior to death, these were not statistically significant. ..
- Multivariate immune defences and fitness in the wild: complex but ecologically important associations among plasma antibodies, health and survivalDaniel H Nussey
Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK, Institute of Infection and Immunity Research, University of Edinburgh, Edinburgh, UK, Centre for Immunity, Infection and Evolution, School of Biological Sciences, University of Edinburgh, Edinburgh, UK, Department of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA, Moredun Research Institute, Pentlands Science Park, Bush Loan, Midlothian, UK
Proc Biol Sci 281:20132931. 2014..Our results highlight both the evolutionary and ecological importance and the complex nature of the immune phenotype in the wild. ..
- Constraints on plastic responses to climate variation in red deerDaniel H Nussey
Institute of Evolutionary Biology, University of Edinburgh, Kings Buildings, West Mains Road, Edinburgh EH9 3JT, UK
Biol Lett 1:457-60. 2005..The presence of such systematic variation in individual plasticity is rarely documented in the wild, and has important implications for our understanding of the environmental dependencies of traits under varying ecological conditions...
- Age-related variation in foraging behaviour in the wandering albatross at South Georgia: no evidence for senescenceHannah Froy
Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, United Kingdom British Antarctic Survey, Natural Environment Research Council, Cambridge, United Kingdom
PLoS ONE 10:e0116415. 2015..This highlights the importance of studies across different wild animal populations to gain a broader perspective on the processes driving variation in ageing rates. ..
- Into the wild: digging at immunology's evolutionary rootsRick M Maizels
Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, UK
Nat Immunol 14:879-83. 2013..Placing the ever-growing understanding of immunological mechanisms in wider real-world contexts is a massive but fundamentally important challenge. ..
- Environmental conditions in early life influence ageing rates in a wild population of red deerDaniel H Nussey
Curr Biol 17:R1000-1. 2007
- Identifying when weather influences life-history traits of grazing herbivoresMichelle Sims
Biomathematics and Statistics Scotland, The Macaulay Institute, Craigiebuckler, Aberdeen AB15 8QH, UK
J Anim Ecol 76:761-70. 2007..The method is of much more general application and could provide valuable insights in other areas of ecology in which sequences of intercorrelated explanatory variables have been collected in space or in time...
- The rate of senescence in maternal performance increases with early-life fecundity in red deerDaniel H Nussey
Ecol Lett 9:1342-50. 2006..These results present rare evidence in support of the disposable soma and antagonistic pleiotropy theories of senescence from a wild vertebrate population and highlight the utility of mixed models for testing theories of ageing...