Affiliation: University College London
Notara M, Ahmed A. Benign prostate hyperplasia and stem cells: a new therapeutic opportunity. Cell Biol Toxicol. 2012;28:435-42 pubmed publisher
..This review focuses on this putative role of stromal stem or stem-like cells in the development of BPH and assesses the potential of targeting the stem cells for the treatment of BPH. ..
Notara M, Daniels J. Characterisation and functional features of a spontaneously immortalised human corneal epithelial cell line with progenitor-like characteristics. Brain Res Bull. 2010;81:279-86 pubmed publisher
Notara M, Alatza A, Gilfillan J, Harris A, Levis H, Schrader S, et al
. In sickness and in health: Corneal epithelial stem cell biology, pathology and therapy. Exp Eye Res. 2010;90:188-95 pubmed publisher
..The clinical precedence for use of stem cell therapy and the accessibility of the transparent stem cell niche make the cornea a unique model for the study of adult stem cells in physiological conditions as well as in disease...
Notara M, Shortt A, Galatowicz G, Calder V, Daniels J. IL6 and the human limbal stem cell niche: a mediator of epithelial-stromal interaction. Stem Cell Res. 2010;5:188-200 pubmed publisher
..STAT3 and IL6 inhibition in 3.1SF cultures significantly reduced HLE colony-forming efficiency, suggesting a previously undetected STAT3-mediated involvement of IL6 in the maintenance of HLE cells in a progenitor-like state...
Notara M, Schrader S, Daniels J. The porcine limbal epithelial stem cell niche as a new model for the study of transplanted tissue-engineered human limbal epithelial cells. Tissue Eng Part A. 2011;17:741-50 pubmed publisher
..These data have significant clinical value as this model can provide information on LESC fate post-transplantation and their ability to respond to injury, which is not possible to study in patients...