Research Topics
Species | R NorburySummaryAffiliation: University of Oxford Country: UK Publications
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Detail Information
Publications
Short-term antidepressant treatment modulates amygdala response to happy facesRay Norbury
Psychopharmacology Research Unit PPRU, Department of Psychiatry, University of Oxford, Warneford Hospital, Neurosciences Building, Headington, Oxford, OX3 7JX, UK
Psychopharmacology (Berl) 206:197-204. 2009..These early effects of antidepressants may be an important component in the therapeutic effects of antidepressant treatment in patients with depression and anxiety...- Increased neural response to fear in patients recovered from depression: a 3T functional magnetic resonance imaging studyR Norbury
Psychopharmacology Research Unit, University of Oxford, Department of Psychiatry, Oxford, UK
Psychol Med 40:425-32. 2010..Whether these changes persist in unmedicated recovered patients is unclear... 
The effects of reboxetine on emotional processing in healthy volunteers: an fMRI studyR Norbury
Department of Psychiatry, University of Oxford, Warneford Hospital, Headington, Oxford, UK
Mol Psychiatry 13:1011-20. 2008..Such adaptations in the neural processing of emotional information support the hypothesis that antidepressants have early effects on emotional processing in a manner which would be expected to reverse negative biases in depression...- Estrogen therapy and brain muscarinic receptor density in healthy females: a SPET studyRay Norbury
Psychopharmacology and Emotion Research Laboratory, University of Oxford, UK
Horm Behav 51:249-57. 2007..In healthy postmenopausal women use of long-term ET is associated with reduced age-related differences in muscarinic receptor binding, and this may be related to serum estradiol levels... - In vivo imaging of muscarinic receptors in the aging female brain with (R,R)[123I]-I-QNB and single photon emission tomographyR Norbury
Institute of Psychiatry, King s College, London, UK
Exp Gerontol 40:137-45. 2005..Thus, in this population of healthy women, there was an age-related reduction in muscarinic receptor density. This may contribute to age-related differences in cognitive function and risk for Alzheimer's disease... - Long-term estrogen therapy and 5-HT(2A) receptor binding in postmenopausal women; a single photon emission tomography (SPET) studyJ Compton
Department of Psychological Medicine, Institute of Psychiatry, Denmark Hill, London SE5 8AF, UK
Horm Behav 53:61-8. 2008..This may reflect increased activity within the serotonergic pathway leading to down-regulation of post-synaptic receptor. Also, increased availability of the 5-HT(2A) receptor in hippocampus is associated with poorer memory function... - Neural response to angry and disgusted facial expressions in bulimia nervosaF Ashworth
Oxford Doctoral Course in Clinical Psychology, University of Oxford, UK
Psychol Med 41:2375-84. 2011..Disgust and anger are of particular theoretical and clinical interest. The current study investigated the neural response to facial expressions of anger and disgust in bulimia nervosa (BN)... - SPET imaging of central muscarinic receptors with (R,R)[123I]-I-QNB: methodological considerationsR Norbury
Psychological Medicine, Institute of Psychiatry, Denmark Hill, London, United Kingdom
Nucl Med Biol 31:583-90. 2004..Here we show that, for this radiotracer, normalizing to a region of negligible specific binding (cerebellum) significantly improves sensitivity when compared to global normalization... - Short-term antidepressant administration reduces negative self-referential processing in the medial prefrontal cortex in subjects at risk for depressionM Di Simplicio
University Department of Psychiatry, Warneford Hospital, Oxford, UK
Mol Psychiatry 17:503-10. 2012.... - Neural correlates of the processing of self-referent emotional information in bulimia nervosaA Pringle
Department of Psychiatry, University of Oxford, Oxford, United Kingdom
Neuropsychologia 49:3272-8. 2011..Different patterns of neural activation between patients and controls may be the result of either habituation to personally relevant negative self beliefs or of emotional blunting in patients... 
Lack of effect of citalopram on magnetic resonance spectroscopy measures of glutamate and glutamine in frontal cortex of healthy volunteersM J Taylor
Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, United Kingdom
J Psychopharmacol 24:1217-21. 2010..This supports the potential for MRS in assessing neuroanatomically specific serotonin-glutamate interactions in the human brain...- Short-term SSRI treatment normalises amygdala hyperactivity in depressed patientsB R Godlewska
University Department of Psychiatry, Warneford Hospital, Oxford, UK
Psychol Med 42:2609-17. 2012..However, it is not clear if these effects occur before, or as a consequence of, changes in clinical state... - The neuroprotective effects of estrogen on the aging brainRay Norbury
Section of Brain Maturation, Department of Psychological Medicine, Institute of Psychiatry, Box P050, De Crespigny Park, London SE5 8AF, UK
Exp Gerontol 38:109-17. 2003..The authors conclude that it is unlikely that estrogen will become a stand-alone treatment for any of these disorders, although there may still be a role as an adjunctive treatment and as a prophylactic measure... - Oestrogen: brain ageing, cognition and neuropsychiatric disorderRay Norbury
Section of Brain Maturation, Department of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London, UK
J Br Menopause Soc 10:118-22. 2004..Here we review research into the effects of oestrogen on brain maturation and function and discuss the role for oestrogen replacement therapy (ERT) as a therapeutic tool... - Risk for depression is associated with neural biases in emotional categorisationStella W Y Chan
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, UK
Neuropsychologia 46:2896-903. 2008..These results highlight a role of the fronto-parietal circuitry in emotional processing and further suggest that negative biases in these neural processes may be involved in risk for depression... - In vivo effects of estrogen on human brainWilliam J Cutter
Section of Brain Maturation, Department of Psychological Medicine, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK
Ann N Y Acad Sci 1007:79-88. 2003..In this article we review research into the effects of estrogen on the human brain and we consider the role for ERT as a therapeutic tool... - Affective modulation of anterior cingulate cortex in young people at increased familial risk of depressionZola N Mannie
University Department of Psychiatry, Warneford Hospital, Oxford, UK
Br J Psychiatry 192:356-61. 2008..We previously found that children of parents with depression showed impaired performance on a task of emotional categorisation...