Affiliation: University College London
- Jejunal haemorrhage in Henoch-Schönlein syndromeK Nistala
Northwick Park Hospital, London, UK
Arch Dis Child 88:434. 2003
- Clinical assessment and core outcome variables are poor predictors of hip arthritis diagnosed by MRI in juvenile idiopathic arthritisK Nistala
Paediatric Rheumatology Department, Birmingham Children s Hospital, Steelhouse Lane, Birmingham B4 6NH, UK
Rheumatology (Oxford) 46:699-702. 2007..To determine the clinical and serological predictors of MRI diagnosed hip arthritis...
- Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environmentKiran Nistala
Rheumatology Unit, University College London Institute of Child Health, London WC1N 1EH, United Kingdom
Proc Natl Acad Sci U S A 107:14751-6. 2010..Therefore therapies targeting the induction of Th17 cells could also attenuate Th17/1 and Th1 effector populations within the inflamed joint...
- CD161 defines the subset of FoxP3+ T cells capable of producing proinflammatory cytokinesAnne M Pesenacker
Rheumatology Unit, UCL Institute of Child Health, University College London, London, United Kingdom
Blood 121:2647-58. 2013..Our data therefore demonstrate that CD161+FoxP3+ T cells are a novel Treg subset, found in health and disease, which display high proinflammatory potential but also exhibit hallmark Treg characteristics...
- Delineation of the innate and adaptive T-cell immune outcome in the human host in response to Campylobacter jejuni infectionLindsey A Edwards
Infectious Diseases and Microbiology, Institute of Child Health, London, United Kingdom
PLoS ONE 5:e15398. 2010..jejuni using an ex-vivo human gut model of infection. Secondly, impact of bacterial-driven dendritic cell activation on T-cell mediated immunity was also sought...
- High expression of the ectonucleotidase CD39 on T cells from the inflamed site identifies two distinct populations, one regulatory and one memory T cell populationHalima Moncrieffe
Rheumatology Unit, University College London, London, United Kingdom
J Immunol 185:134-43. 2010..Our data suggest that in human CD4(+) T cells from the inflamed site, CD39 can be highly expressed on two populations, one regulatory and the other of a memory phenotype...
- Biologic predictors of extension of oligoarticular juvenile idiopathic arthritis as determined from synovial fluid cellular composition and gene expressionPatricia J Hunter
Rheumatology Unit, University College London Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
Arthritis Rheum 62:896-907. 2010....
- Th17 and regulatory T cells: rebalancing pro- and anti-inflammatory forces in autoimmune arthritisKiran Nistala
Rheumatology Unit, Institute of Child Health, University College London, London, UK
Rheumatology (Oxford) 48:602-6. 2009..Anti-rheumatic biologic therapies may offer a means of restoring the Th17/Treg balance in favour of Tregs and thereby re-establishing immune tolerance...
- Interleukin-17-producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbersKiran Nistala
University College London, London, UK
Arthritis Rheum 58:875-87. 2008....
- Co-existent sickle cell disease and juvenile rheumatoid arthritis. Two cases with delayed diagnosis and severe destructive arthropathyK Nistala
Paediatric Rheumatology Unit, Great Ormond Street Hospital, London, England
J Rheumatol 28:2125-8. 2001..The resultant ischemia and corresponding inflammatory infiltrates could in turn worsen existing synovial proliferation and cartilage destruction as well as trigger further sickling...