Søren U Nielsen

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. ncbi request reprint Human T cells resistant to complement lysis by bivalent antibody can be efficiently lysed by dimers of monovalent antibody
    Soren U Nielsen
    Department of Microbiology and Immunology, University of Newcastle upon Tyne, Medical School, England
    Blood 100:4067-73. 2002
  2. doi request reprint Intravascular transfer contributes to postprandial increase in numbers of very-low-density hepatitis C virus particles
    Daniel J Felmlee
    Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK
    Gastroenterology 139:1774-83, 1783.e1-6. 2010
  3. doi request reprint Insulin resistance and low-density apolipoprotein B-associated lipoviral particles in hepatitis C virus genotype 1 infection
    Simon H Bridge
    Institute of Cellular Medicine, William Leech Building, The Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK
    Gut 60:680-7. 2011
  4. pmc Association between hepatitis C virus and very-low-density lipoprotein (VLDL)/LDL analyzed in iodixanol density gradients
    Søren U Nielsen
    Liver Research Group, School of Clinical Medical Sciences, University of Newcastle, England
    J Virol 80:2418-28. 2006
  5. pmc Characterization of hepatitis C RNA-containing particles from human liver by density and size
    Søren U Nielsen
    Liver Research Group, Clinical Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK
    J Gen Virol 89:2507-17. 2008
  6. pmc Characterization of the genome and structural proteins of hepatitis C virus resolved from infected human liver
    Søren U Nielsen
    School of Clinical Medical Sciences, Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH, UK
    J Gen Virol 85:1497-507. 2004

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Human T cells resistant to complement lysis by bivalent antibody can be efficiently lysed by dimers of monovalent antibody
    Soren U Nielsen
    Department of Microbiology and Immunology, University of Newcastle upon Tyne, Medical School, England
    Blood 100:4067-73. 2002
    ..The monovalent CD3 mAb dimer may have potential for development as an agent for immunotherapy of T-cell leukemia...
  2. doi request reprint Intravascular transfer contributes to postprandial increase in numbers of very-low-density hepatitis C virus particles
    Daniel J Felmlee
    Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK
    Gastroenterology 139:1774-83, 1783.e1-6. 2010
    ..We sought to determine if factors that affect triglyceride-rich lipoprotein (TRL) metabolism alter the density and dynamics of HCV particles in the plasma of patients with chronic HCV infection...
  3. doi request reprint Insulin resistance and low-density apolipoprotein B-associated lipoviral particles in hepatitis C virus genotype 1 infection
    Simon H Bridge
    Institute of Cellular Medicine, William Leech Building, The Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK
    Gut 60:680-7. 2011
    ..Objective To measure LVP in patients with chronic hepatitis C genotype 1 (CHC-G1) and examine metabolic determinants of LVP load. Patients 51 patients with CHC-G1 infection...
  4. pmc Association between hepatitis C virus and very-low-density lipoprotein (VLDL)/LDL analyzed in iodixanol density gradients
    Søren U Nielsen
    Liver Research Group, School of Clinical Medical Sciences, University of Newcastle, England
    J Virol 80:2418-28. 2006
    ..Immunoprecipitation analysis showed that ApoB remained associated with HCV after treatment of serum with deoxycholic acid or NP-40, whereas ApoE was removed from HCV with these detergents...
  5. pmc Characterization of hepatitis C RNA-containing particles from human liver by density and size
    Søren U Nielsen
    Liver Research Group, Clinical Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK
    J Gen Virol 89:2507-17. 2008
    ..This HCV was associated with ApoB, ApoE and viral glycoprotein E2, similar to viral particles circulating in serum. Our results indicate that the association between HCV and VLDL occurs in the liver...
  6. pmc Characterization of the genome and structural proteins of hepatitis C virus resolved from infected human liver
    Søren U Nielsen
    School of Clinical Medical Sciences, Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH, UK
    J Gen Virol 85:1497-507. 2004
    ..Glycoprotein E2 was 62 kDa before and 36 kDa after deglycosylation, but E2-P7 was not detected. This was in contrast to recombinant sources of E2 which contain E2-P7...