Martin J H Nicklin
Affiliation: University of Sheffield
- The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytesDavid Magne
Division of Rheumatology, Department of Internal Medicine, University Hospital and Department of Pathology and Immunology, University of Geneva School of Medicine, Geneva, Switzerland
Arthritis Res Ther 8:R80. 2006..It remains to be determined whether circulating IL-1F8 can contribute to joint inflammation in rheumatoid arthritis...
- Alterations in the self-renewal and differentiation ability of bone marrow mesenchymal stem cells in a mouse model of rheumatoid arthritisSindhu T Mohanty
Department of Human Metabolism, University of Sheffield, Sheffield S10 2RX, UK
Arthritis Res Ther 12:R149. 2010..In this study we test the hypothesis that the onset of inflammatory arthritis is associated with altered self-renewal and differentiation of bone marrow MSC, which alters the composition of the BM microenvironment...
- A sequence-based map of the nine genes of the human interleukin-1 clusterMartin J H Nicklin
Division of Genomic Medicine, University of Sheffield, Royal Hallamshire Hospital, Sheffield S10 2JF, UK
Genomics 79:718-25. 2002..The gene order relates to the evolutionary relationship between the genes. Key features of exon boundaries are conserved. There is no evidence for other IL-1 family members within the cluster...
- Decreased fat mass in interleukin-1 receptor antagonist-deficient mice: impact on adipogenesis, food intake, and energy expenditureEmmanuel Somm
Endocrine Unit, Department of Internal Medicine, University Hospital Geneva, 24, Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
Diabetes 54:3503-9. 2005..Taken together, we show that IL-1Ra is an important regulator of adipogenesis, food intake, and energy expenditure...