Research Topics
Genomes and GenesSpecies | Luigi NibaliSummaryAffiliation: University College London Country: UK Publications
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Detail Information
Publications
Association of serum interleukin-6 concentration with a functional IL6 -6331T>C polymorphismAndrew J P Smith
Centre for Cardiovascular Genetics, Department of Medicine, University College London, London, UK
Clin Chem 54:841-50. 2008..Interleukin-6 (IL-6) concentrations vary substantially among individuals. This study aimed to identify novel genetic markers to explain these differences...
Periodontitis and redox status: a reviewLuigi Nibali
Periodontology Unit and Department of Clinical Research, UCL Eastman Dental Institute, University College London, 256 Gray s Inn Road, London WC1X 8LD, UK
Curr Pharm Des 19:2687-97. 2013..Finally, the review provides an overview of possible intervention pathways for the use of antioxidants as adjuncts to mechanical biofilm removal for the treatment of periodontitis...
Hereditary gingival hyperplasia associated with amelogenesis imperfecta: a case reportLuigi Nibali
UCL Eastman Dental Institute, London, England
Quintessence Int 43:483-9. 2012..This phenotype, similar to what has been described in other families, may represent a new syndrome caused by an as-yet unknown genotype...
Radiographic bone fill of peri-implantitis defects following nonsurgical therapy: report of three casesLuigi Nibali
Department of Clinical Research, UCL Eastman Dental Institute and Hospital, London, England
Quintessence Int 42:393-7. 2011..This case report shows that a degree of clinical resolution and radiographic bone fill can occur without the use of adjunctive antibiotics in peri-implantitis lesions of patients with periodontitis...
Clinical and radiographic outcomes following non-surgical therapy of periodontal infrabony defects: a retrospective studyLuigi Nibali
Periodontology Unit and Division of Clinical Research, Eastman Dental Institute and Hospital, University College London UCL, London, UK
J Clin Periodontol 38:50-7. 2011..The aim of this retrospective study was to analyse the clinical and radiographic response of infrabony defects following non-surgical therapy and to detect the factors associated with such a response...
IL6 -174 genotype associated with Aggregatibacter actinomycetemcomitans in IndiansL Nibali
Periodontology Unit and Division of Clinical Research, Eastman Dental Hospital, University College London UCL, London, UK
Oral Dis 17:232-7. 2011..The aim of this study was to analyse associations between Interleukin-6 (IL6) single nucleotide polymorphisms and presence and levels of A. actinomycetemcomitans and other subgingival microbes in a rural Indian population...
Association between interleukin-6 -174 polymorphism and Aggregatibacter actinomycetemcomitans in chronic periodontitisL Nibali
Division of Clinical Research, University College London, Eastman Dental Institute, London, UK
J Periodontol 81:1814-9. 2010....
Genetic variants associated with neutrophil function in aggressive periodontitis and healthy controlsL Nibali
Periodontology Unit and Division of Clinical Research University College London, Eastman Dental Institute London, UK
J Periodontol 81:527-34. 2010..The aim of this study is to test whether a clinical diagnosis and specific genetic variants are associated with neutrophil activity in subjects with AgP and healthy subjects...
Periodontal infectogenomicsLuigi Nibali
Periodontology Unit and Division of Clinical Research, UCL Eastman Dental Institute, University College London, London, UK
J Med Microbiol 58:1269-74. 2009..Mechanisms of interaction between genetic and microbiological factors and prospects for future studies will be discussed...
Association between periodontitis and common variants in the promoter of the interleukin-6 geneL Nibali
Periodontology Unit, University College London, Eastman Dental Institute, London, UK
Cytokine 45:50-4. 2009..This association is stronger for LAgP than for other periodontal disease phenotypes...
A familial analysis of aggressive periodontitis - clinical and genetic findingsL Nibali
Periodontology Unit, Eastman Dental Institute and Hospital, University College London, London, UK
J Periodontal Res 43:627-34. 2008....
Vitamin D receptor polymorphism (-1056 Taq-I) interacts with smoking for the presence and progression of periodontitisLuigi Nibali
Department of Periodontology, Eastman Dental Institute and Hospital, University College London UCL, London, UK
J Clin Periodontol 35:561-7. 2008..The aim of this analysis was to investigate the relationship between a vitamin D receptor (VDR) polymorphism and the diagnosis and progression of periodontitis...
Severe periodontitis is associated with systemic inflammation and a dysmetabolic status: a case-control studyLuigi Nibali
Periodontology Unit, Eastman Dental Institute and Hospital, University College London, London, UK
J Clin Periodontol 34:931-7. 2007..The aim of this study was to investigate the association between severe periodontitis and increase in inflammatory and metabolic risk factors for cardiovascular disease...
Association between interleukin-6 promoter haplotypes and aggressive periodontitisLuigi Nibali
Periodontology Unit, University College London, London, UK
J Clin Periodontol 35:193-8. 2008..Interleukin-6 (IL-6) polymorphisms have been shown to affect IL-6 promoter activity. This study investigated the possible role of IL-6 genetic polymorphisms and haplotypes in the predisposition to aggressive periodontitis (AgP)...
Interleukin-6 polymorphisms are associated with pathogenic bacteria in subjects with periodontitisLuigi Nibali
Eastman Dental Hospital, University College London, London, UK
J Periodontol 79:677-83. 2008..The aim of this study was to investigate the association between IL-6 polymorphisms and periodontopathogenic bacteria in a larger, ethnically mixed population of subjects with periodontitis...
No association between A actinomycetemcomitans or P gingivalis and chronic or aggressive periodontitis diagnosisLuigi Nibali
Periodontology Unit and Department of Clinical Research, UCL Eastman Dental Institute, London, UK
Quintessence Int 43:247-54. 2012..The aim of this analysis was to assess if clinical diagnosis or other subject factors showed association with the presence of Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in a cohort of periodontitis patients...
Association between interleukin-6 polymorphisms and periodontitis in Indian non-smokersFernando Franch-Chillida
Periodontology Unit, Eastman Dental Hospital, University College London UCL, London, UK
J Clin Periodontol 37:137-44. 2010..The aim of this study was to investigate the association between five SNPs in the IL-6 promoter region and the periodontal status of a rural Indian population...
Low prevalence of subgingival viruses in periodontitis patientsLuigi Nibali
Periodontology Unit, Eastman Dental Institute, London WC1X 8LD, UK
J Clin Periodontol 36:928-32. 2009..The aim of this study was to analyse the presence of herpesvirus DNA in subgingival plaque samples of patients with different forms of periodontitis and in healthy periodontia...
Latent variable approach to correct errors in radiographic measurementsYu Kang Tu
Department of Periodontology, Leeds Dental Institute, University of Leeds, Leeds, UK
Eur J Oral Sci 118:642-8. 2010..Whilst both LVM and CFM achieve excellent results, LVM is more flexible in handling missing values, and may provide better results when treatment effects are large...
Periodontal infections cause changes in traditional and novel cardiovascular risk factors: results from a randomized controlled clinical trialMohamed Parkar
Department of Periodontology, Eastman Clinical Investigation Centre, University College London, London, United Kingdom
Am Heart J 151:977-84. 2006..CONCLUSIONS: Our findings suggest that intensive periodontal treatment reduces systemic inflammatory markers and systolic BP, and improves lipid profiles with subsequent changes in cardiovascular risk when compared to standard therapy...
Clinical review: Association between metabolic syndrome and periodontitis: a systematic review and meta-analysisLuigi Nibali
Periodontology Unit and Department of Clinical Research, University College London Eastman Dental Institute, 256 Gray s Inn Road, London WC1X 8LD, United Kingdom
J Clin Endocrinol Metab 98:913-20. 2013..Several epidemiological studies have reported an association between metabolic syndrome (MetS) and periodontal diseases (PDs). The aim of this systematic review was to investigate the existence and magnitude of this association...
Oxidative stress, chronic inflammation, and telomere length in patients with periodontitisStefano Masi
Vascular Physiology Unit, Institute of Child Health, University College London, London, UK
Free Radic Biol Med 50:730-5. 2011..We conclude that shorter telomere lengths are associated with a diagnosis of periodontitis and their measures correlate with the oxidative stress and severity of disease...
Differential regulation of circulating levels of molecular chaperones in patients undergoing treatment for periodontal diseaseAlireza Shamaei-Tousi
Division of Microbial Diseases, UCL Eastman Dental Institute, University College London, London, United Kingdom
PLoS ONE 2:e1198. 2007..We have used periodontitis and its treatment as a model of inflammation in the human to determine its effects on levels of circulating HSP10, HSP60 and BiP...
Adjunctive benefits of systemic amoxicillin and metronidazole in non-surgical treatment of generalized aggressive periodontitis: a randomized placebo-controlled clinical trialAdrian Guerrero
Department of Periodontology and Eastman Clinical Investigation Centre, Eastman Dental Institute and Hospital, University College London, London, UK
J Clin Periodontol 32:1096-107. 2005..CONCLUSIONS: These data indicate that a 7-day adjunctive course of systemic metronidazole and amoxicillin significantly improved the short-term clinical outcomes of full-mouth non-surgical periodontal debridement in subjects with GAP...
Treatment of periodontitis and endothelial functionMaurizio S Tonetti
Department of Oral Health and Diagnostic Sciences, University of Connecticut Health Center, Farmington, USA
N Engl J Med 356:911-20. 2007..Systemic inflammation may impair vascular function, and epidemiologic data suggest a possible link between periodontitis and cardiovascular disease...
